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  • 1
    Electronic Resource
    Electronic Resource
    On-line solution stability determination of pharmaceuticals by capillary electrophoresis (1993)
    Springer
    Chromatographia 37 (1993), S. 176-178 
    Details
    ISSN: 1612-1112
    Keywords: Capillary electrophoresis ; Stability testing ; Ranitidine related impurities
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary Good agreement between the impurity levels in a batch of a related impurity of ranitidine were obtained by CE and HPLC. A solution of the impurity was positioned on the CE autosampler and analysed sequentially. The extent of degradation was monitored by loss of main peak and the formation of two principal degradation products. It was found that after 9.25 hours only 2% area/area of the original impurity remained. Buffering of the sample solution to pH 7 was shown to minimise this degradation. Unattended in-situ stability testing of an solution of the impurity in water was performed by CE.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02275857
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Making real neural nets: design criteria (1992)
    Springer
    Medical & biological engineering & computing 30 (1992), S. CE33 
    Details
    ISSN: 1741-0444
    Keywords: Cell guidance ; Neural nets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Neural nets may be assembled with living nerve cells in vitro to test theories about neural processing and the ways in which patterns develop in the nervous system, and to test ideas about plasticity and learning in processing systems. This may benefit the design of computer systems and prosthetic devices. Extracting information from such nets can be achieved by means of intracellular and extracellular electrodes and fluorescent dyes. Patterning of cells may be achieved using microfabrication techniques, and extracellular electrodes can be combined within the patterned substrate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02446176
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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