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  • 1
    Digitale Medien
    Digitale Medien
    Shared and specific allergenic and antigenic components in the two sexes of American cockroach—Periplaneta americana (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 20 (1990), S. 0 
    Details
    ISSN: 1365-2222
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: The whole body extracts (WBEs) of female and male cockroaches (Periplaneta americana; Pa) were prepared separately to study the specific and/or shared allergenic and antigenic components in the two sexes. These two extracts were skin-tested on 170 respiratory allergy patients and 52 (30–6%) of them elicited a markedly positive cutaneous reaction (2+ to 4+) to any one or both the WBEs. Of these 52 patients, 32 (61·5%) produced a 2+ to 4+ response to only one, and the remaining 20 (38·5%) to both the extracts. In female and male RASTs to Pa both the extracts produced dose-related inhibition. Using rabbit anti-Pa female serum: (1) immuno-diffusion experiments resulted in lines of identity with the two extracts, and (2) the two-dimensional immunoelectrophoresis of Pa female and Pa male WBEs elicited 12 and nine precipitin peaks, respectively. In partial purification studies, only fraction Pa(F)III (∼ 50 kD) of Pa female WBE and Pa(M)I (〈inlineGraphic alt="geqslant R: gt-or-equal, slanted" extraInfo="nonStandardEntity" href="urn:x-wiley:09547894:CEA59:ges" location="ges.gif"/〉 600 kD) and Pa(M)III (∼ 50 kD) fractions of Pa male WBE revealed significant allergen activity both on skin testing and also in RAST inhibition studies. These results provide evidence for the presence of shared as well as specific allergenic and antigenic components in the two sexes of American cockroach.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2222.1990.tb02776.x
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  • 2
    Digitale Medien
    Digitale Medien
    Bronchiectasis in children with lymphocytic interstitial pneumonia and acquired immune deficiency syndrome (1992)
    Springer
    Pediatric radiology 22 (1992), S. 603-606 
    Details
    ISSN: 1432-1998
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract In a review of 77 HIV positive children seen between 1981 and 1990, 32 were diagnosed as having lymphocytic interstitial pneumonitis). Four of the LIP group developed bronchiectasis, a finding not previously reported. The precise factors leading to the bronchiectasis are unclear. All patients had chronically consolidated lung with volume loss. A history of recurrent bacterial superinfection was not noted in any of the cases. With more cases of HIV positive children living longer, bronchiectasis, long known to occur in primary immunologic disorders, will probably be more frequently noted.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02015366
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  • 3
    Digitale Medien
    Digitale Medien
    Occurrence and significance of precipitating antibodies against thermophilic actinomycetes in the sera of dairy herd workers, Nangali, Delhi (1991)
    Springer
    Antonie van Leeuwenhoek 59 (1991), S. 167-175 
    Details
    ISSN: 1572-9699
    Schlagwort(e): precipitating antibodies to thermophilic actinomycetes ; Faenia rectivirgula ; Saccharomonospora viridis ; dairy herd workers ; Ouchterlony's double diffusion test ; counterimmunoelectrophoresis ; enzyme-linked immunosorbent assay
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract The study was prompted by the lack of information on the role of thermophilic actinomycetes in hypersensitivity pneumonitis in India. It reports the occurrence of precipitating antibodies against clinically important thermophilic actinomycetes in the sera of a population sample of dairy herd workers, Nangali, Delhi. Of 112 workers investigated, 28 (25%) showed precipitins againstFaenia rectivirgula, 4 (3.2%) againstSaccharomonospora viridis, 2 againstThermoactinomyces thalpophilus and one each againstT. vulgaris andT. sacchari. The results of enzyme-linked immunosorbent assay (ELISA) indicated that IgG antibody activity againstF. rectivirgula was significantly higher in the symptomatic group than in the asymptomatic group (p〈0.05) of workers and the controls (p〈0.01). Significant difference inF. rectivirgula IgG activity was also obtained between the precipitin-positive symptomatic group and the precipitin-positive asymptomatic group (p〈 0.05). In strong contrast, the IgG antibody activity againstT. thalpophilus was found to be uniformly low. A limited aeromicrobiological sampling of the dairy farm revealedS. viridis (55.8%) to be the commonest species followed byT. vulgaris (19.2%),T. thalpophilus (18.5%),F. rectivirgula (5%) andT. sacchari (15%). On the basis of suggestive clinical and laboratory findings, farmer's lung disease was suspected in four dairy herd workers. A comprehensive clinical evaluation including pulmonary function studies on the dairy herd workers and their long-term follow-up is indicated to determine the extent of respiratory morbidity caused byF. rectivirgula, S. viridis, T. thalpophilus, T. sacchari andT. vulgaris in India.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00580656
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  • 4
    Digitale Medien
    Digitale Medien
    Epidemiological correlates between consumption of Indian chewing tobacco and oral cancer (1990)
    Springer
    European journal of epidemiology 6 (1990), S. 219-222 
    Details
    ISSN: 1573-7284
    Schlagwort(e): Epidemiology ; Chewing tobacco ; Oral cancer
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The problem of cancer is universal; the only variation occurs in the type, site or other clinicoepidemiological parameters. Peculiarly enough, oral cancers caused by chewing tobacco are common in India and some parts of the Indian sub-continent. Oral cancers caused by other carcinogens are not common in these areas. The present study shows a significant association (P L 0.001) between the use of Indian chewing tobacco and oral cancer. Number of quids, mean quantity of tobacco and mean duration of keeping the quids in the mouth had direct dose and effect relationships in causation of oral cancer. A dose of 10 gms of chewing tobacco for about 26 years was observed to have produced cancerous lesions in the buccal cavity.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00145797
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  • 5
    Digitale Medien
    Digitale Medien
    Chromatographic resolution of racemic amines, carboxylic acids, and alcohols by a new homochiral reagent derived fromendo-borneol (1992)
    Springer
    Chromatographia 34 (1992), S. 48-50 
    Details
    ISSN: 1612-1112
    Schlagwort(e): Column liquid chromatography ; Diastereomer separation ; Chiral derivatizing agent ; Chiral oxazolidin-2-one
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Summary Chromatographic separation of racemic amines, carboxylic acids and alcohols can be achieved with excellent resolution as measured in terms of the chromatographic separation factor α by derivatization with a homochiral oxazolidin-2-one easily prepared in three steps fromendo-borneol. The resolved materials can be isolated in excellent yields by cleavage of the resultant diastereomers using conventional methods, which also allow recovery of the chiral resolving agent for re-use.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02290458
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