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  • 1
    Electronic Resource
    Electronic Resource
    Adult-onset lysosomal storage disease in a Schipperke dog: clinical, morphological and biochemical studies (1993)
    Springer
    Acta neuropathologica 86 (1993), S. 306-312 
    Details
    ISSN: 1432-0533
    Keywords: Canine galactosialidosis ; Morphology ; Biochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An adult-onset lysosomal storage disorder was diagnosed in a 5-year-old Schipperke dog with progressive cerebellar and central vestibular signs. It was characterized by cerebellar atrophy with extensive loss of Purkinje and granular cells, and hydrocephalus. Enlarged and vacuolated neurons were observed in spinal cord and brain; pancreatic centrolobular and islet cells were also vacuolated. Ultrastructurally, enlarged secondary lysosomes laden with lamellated membrane structures were present in neurons and empty enlarged vacuoles were found in pancreatic centroacinar, ductal, and islet cells. On frozen sections neurons stained with Ricinus communis agglutinin-I and wheat germ agglutinin. On paraffin sections neurons stained with luxol fast blue, periodic acid-Schiff, Concanavalia ensiformis agglutinin, and were autofluorescent. These findings indicate an accumulation of glycolipids containing terminal β-galactosyl and α-sialyl residues, and N-linked oligosaccharides. Tissue activity of lysosomal β-galactosidase was 50% of normal and the activity of β-hexosaminidase was elevated. Brain lipid-bound sialic acid was twice normal, with a small increase of GM1-ganglioside, but there was a significant elevation of GM2 (GD2) and GM3 (GD3). In addition, significant elevations of sialylated and non-sialylated oligosaccharides were noted. These clinical, biochemical and pathological findings are similar to those observed in human patients with adult-onset galactosialidosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00304147
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  • 2
    Electronic Resource
    Electronic Resource
    Scanning electron acoustic microscopy of indentation-induced cracks and residual stresses in ceramics (1990)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 57 (1990), S. 1870-1872 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The ability of scanning electron acoustic microscopy (SEAM) to characterize ceramic materials is assessed. SEAM images of Vickers indentations in SiC whisker-reinforced alumina clearly reveal not only the radial cracks, the length of which can be used to estimate the fracture toughness of the material, but also reveal strong contrast, interpreted as arising from the combined effects of lateral cracks and the residual stress field left in the SiC whisker-reinforced alumina by the indenter. The strong contrast is removed after the material is heat treated at 1000 °C to relieve the residual stresses around the indentations. A comparison of these observations with SEAM and reflected polarized light observations of Vickers indentations in soda-lime glass both before and after heat treatment confirms our interpretation of the strong contrast.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.104019
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Evidence of hexagonal diamond in plasma-deposited carbon films (1994)
    Springer
    Journal of materials science 29 (1994), S. 4962-4966 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Hexagonal diamond grains of ∼30 nm diameter together with graphite and SiC are seen in predominantly amorphous carbon films deposited at low temperature on Si substrates from a CH4 plasma vapour source. The different crystalline phases are identified by grazing-angle X-ray diffraction which allows for substrate rotation and tilting to enable the 2θ peaks to be correlated with the angular displacements of specific planes. Electron energy-loss spectroscopy shows the chemical composition of the films to be predominantly carbon with traces of oxygen. Raman spectroscopy shows the peaks to be associated with amorphous carbon and graphite, together with a peak at 1170 cm−1 which is attributed to microcrystalline hexagonal diamond.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01151085
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Computation of normal impinging jets in cross-flow and comparison with experiment (1991)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 13 (1991), S. 1225-1233 
    Details
    ISSN: 0271-2091
    Keywords: Jets ; Vortex flows ; k-ε model ; Finite volume ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The PHOENICS code has been used to model the flow field surrounding subsonic and underexpanded jets impinging on a ground plane in the presence of a cross-flow, for cases with both a fixed ground plane and a ‘rolling road’. The standard k-ε turbulence model is used, without correction factors. It is confirmed that this overpredicts the free jet entrainment rate; the wall jet spreading rate is slightly underpredicted but the initial thickness is too high. Agreement with experiment is, nevertheless, much better than for previous calculations, showing the importance of the extent of the grid used. The ground vortex formed in cross-flow is shown to move with varying effective velocity ratio and with rolling road operation in the same manner as experimentally observed. Ground vortex self-similarity is also accurately predicted with the numerical modelling.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650131003
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    Paper (German National Licenses)
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