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  • 1990-1994  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 65 (1994), S. 776-778 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: In order to investigate weak link properties in the Tl1Ba2Ca2Cu3Ox[Tl-(1223)] system, we measured the transport properties of artificially grown grain boundaries in Tl-(1223) films. Epitaxial thin films were grown on SrTiO3 bicrystal substrates with five tilt angles of 5°, 10°, 15°, 24°, and 36.8°. We found that the grain boundaries Jc (Jcg.b.) of large tilt angles (θ≥15°) at 77 and 5 K were substantially less than intragrain Jc(Jcg) and limited by a weak link. However, the Jcg.b./Jcg values for low tilt angle grain boundaries (θ≤10°) were almost unity. Moreover, magnetic-field history dependent Jc values for low tilt angle grain boundaries were not observed in a low magnetic field (〈0.1 T). These data indicate that the low tilt angle grain boundaries do not work as a weak link and retain high Jc.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Three transgenic mouse lines, ICR-PVRTg1, ICR-PVRTg5, and ICR-PVRTg21, which are susceptible to poliovirus, have been established by introducing the human gene for poliovirus receptor (PVR) into the genome of mouse strain ICR. Genetic characterizations of the PVR gene were carried out on these mouse lines to define the approximate copy number, insertion site, and expression of the transgene in the central nervous system (CNS). The transgene was integrated in the chromosome 4, 12, and 13 of ICR-PVRTg1, ICR-PVRTg5 and ICR-PVRTg21 mice, respectively, and was stably transmitted to progeny mice. ICR-PVRTg1 appeared to have the most abundant copy numbers of the transgene and showed the highest level of PVR mRNA and membrane associated PVR protein in the CNS among the three mouse lines. Those in ICR-PVRTg21 and ICR-PVRTg5 were at intermediate and lowest levels, respectively. In the CNS, PVR mRNA was detected at high levels only in neurons of the spinal cord and brain stem where poliovirus can replicate, suggesting that the PVR mRNA expression confers cell specificity to poliovirus in the CNS. ICR-PVRTg1 and ICR-PVRTg5 showed the highest and the lowest sensitivity to poliovirus, respectively, whereas ICR-PVRTg21 was in-between. These results may suggest that poliovirus sensitivity of the mice is attributed to relative levels of PVR expression.
    Type of Medium: Electronic Resource
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