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  • 1
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Genes affecting acetylcholine (ACh) levels without influencing choline acetyltransferase activity have been identified in Caenorhabditis elegans. We have examined one such gene, unc-18. We isolated a transposon-insertion allele for unc-18 and used it to clone a genomic region containing the unc-18 locus. The unc-18 location within this region was determined by rescuing the unc-18 mutant phenotype in a germline transformation experiment and identifying transcripts affected by four independent unc-18 mutations. A single-sized poly(A)+ RNA was synthesized from the gene. Expression of the transcript appears to be stage specific: The transcript is found in abundance at the early larval stage but in decreased amounts at the fourth larval and the adult stages. These results show that the unc-18 gene plays a role in development as well as in the kinetics of ACh metabolism.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 19 (1992), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The dimensional change of tissue conditioners with time was measured until 4 weeks after mixing. Shrinkage of the materials was evaluated in relation to particle size in powder and the EtOH content in liquid. The dissolution of EtOH and plasticizer were also measured to investigate the relation to dimensional change. Shrinkage with time was recorded. The smaller the particle size in powder and the more EtOH in liquid, the greater the shrinkage rate. The smaller the particle size in the powder and the more EtOH contained in the liquid, the greater the dissolution of EtOH. The dissolution of BPBG was below 1/100 comparing that of EtOH and no difference was recognized by particle size and EtOH content.On the basis of these results it is suggested that the dissolution of EtOH is related to shrinkage of tissue conditioners with time and that the component particle size in the powder and EtOH content in the liquid have a significant influence on dissolution of EtOH associated with shrinkage.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 21 (1994), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The effect of both the ethyl alcohol content of liquids and the type of plasticizer on the viscoelastic properties after gelation of tissue conditioners was studied by means of a stress relaxation test. The results are summarized as follows. The liquids containing the larger percentages of ethyl alcohol produced the larger flow after gelation. Furthermore, the ethyl alcohol content had a significant influence on changes in viscoelastic properties with the passage of time. Flow properties were found to reduce rapidly with time of storage with an increase in the ethyl alcohol content. The use of benzyl benzoate produced the larger flow after gelation than dibutyl phthalate, which in turn produced the larger flow than butyl phthalyl butyl glycolate. The type of plasticizer, however, was found to have no influence on changes in viscoelastic properties with the passage of time.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 63 (1993), S. 899-901 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We investigated iodine doping in mercury cadmium telluride (Hg1−xCdxTe) grown by direct alloy growth using metalorganic chemical vapor deposition, with isopropyl-iodine (IPI) as the dopant source. The memory effect in iodine doping is much smaller than that in indium doping. We confirmed by secondary ion mass spectroscopy (SIMS) measurement that sharp dopant transitions (0.2 μm/decade) were obtained by switching off the IPI during growth. The electron concentration at 77 K was linearly proportional to the dopant partial pressure from 5×1015 to 2×1018 cm−3. We confirmed by SIMS that 20%–100% of the iodine was active as a donor. The Hall coefficient shows classical n-type extrinsic behavior from 20 to 300 K. The electron mobility was as high as that in an indium-doped sample. The layer with a Cd fraction of x=0.23, doped to 5×1016 cm−3, exhibited a mobility of 4.7×104 cm2/V s at 77 K and 6.9×104 cm2/V s at 20 K. The iodine in the HgCdTe layers was thermally stable. We found no variation in the electrical properties and the iodine depth profile after annealing at 400 °C for 2 h.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 131 (1994), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We report a patient with a congenital ichthyosiform eruption, sensorineural deafness, vascularizing keratitis and pannus formation, and hypotrichosis, who developed recalcitrant fungating candidal plaques on the skin. There was no family history of similar disease, or of consanguinity. The steroid sulphatase level in the keratin was within normal limits, and this finding excluded a diagnosis of X-linked recessive ichthyosis. Treatment with oral fluconazole for 14 weeks resulted in complete resolution of the fungating lesions, and there has been no evidence of recurrence during a 12-month follow-up period.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 28 (1993), S. 0 
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 47 (1991), S. 1697-1700 
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    International urogynecology journal 3 (1992), S. 64-70 
    ISSN: 1433-3023
    Keywords: Asymptomatic ; Microhematuria
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Asymptomatic microhematuria is not a rare phenomenon among apparently healthy individuals, and the incidence of such hematuria increases significantly with age. Some investigators report that the cause of hematuria is renal glomerular disease in more than 50% of patients, and urological malignancies in 1.0%–13%. On initial examination, urine sediments must be searched for evidence of renal glomerular disease, such as RBC casts and dysmorphic RBCs. If the patients were diagnosed to have glomerular disease, follow-up studies, without any extended examination or therapy are recommended, because their prognosis is usually favorable. The next step is to perform thorough urological examinations, including urine cytology, cystoscopy, abdominal ultrasound, and intravenous pyelography, to detect serious underlying disease. Even if no significant findings were observed after the extensive urological examinations, careful follow-up studies should be performed at 6–12-month intervals for 3 years, using the same methods.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The nucleotide sequences of the 5′-portion of the HCV genome, consisting of 2672 nucleotides, were determined by analysis of clones derived from 5 different patients with liver cirrhosis and hepatocellular carcinoma. Comparison of 5 genomes and 8 isolates already reported demonstrated the significant genome diversity in the structural regions. Genetic divergence was outstanding in the envelope regions (E1 and NS1/E2, 〉59.7% identity) in contrast to the sequence conservation of the 5′ non-coding (〉93.8% identity) or core regions (〉82.0% identity). Although hypervariable regions were found in the NS1/E2 region as reported, hydropathicity was maintained for all clones, reflecting the biological functions of these regions.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Journal of thermal analysis and calorimetry 38 (1992), S. 1767-1774 
    ISSN: 1572-8943
    Keywords: excess enthalpies ; excess heat capacities ; binary mixtures
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung An binären Gemischen aus Acetonitril, Dimethylformamid und Benzol wurden bei 298.15 K die Überschußenthalpien und die isobaren Überschußwärmekapazitäten gemessen. Die Überschußenthalpie von Acetonitril + Benzol ist positiv, die von Acetonitril + Dimethylformamid ist negativ. Die Überschußenthalpie ist bei Dimethylformamid positiv und wie bereits berichtet [1] annähernd Null. Die Überschußwärmekapazität von Acetonitril + Benzol und Benzol + Dimethylformamid wechselt bei Zunahme von Benzol das Vorzeichen von negativ zu positiv. Die von Acetonitril + Dimethylformamid ist nicht einfach. An beiden Enden der Molenbruchskaie ist sie leicht positiv und nicht allzu negativ in der Mitte der Molenbruchskale. Die Kurve flacht in dieser Region ab.
    Notes: Abstract Excess enthalpies and excess isobaric heat capacities of binary mixtures consisting of acetonitrile, dimethylformamide and benzene were measured at 298.15 K. Excess enthalpy of acetonitrile + benzene is positive and that of acetonitrile + dimethylformamide is negative. That of dimethylformamide + benzene is positive and nearly equals to zero as shown in the previous report [1]. Excess heat capacities of acetonitrile + benzene and benzene + dimethylformamide change sign from negative to positive with increase of benzene. That of acetonitrile + dimethylformamide is not simple. It is slightly positive near both ends of mole fraction and not so large negative in the middle of mole fraction. The curve tends to flatten in that region.
    Type of Medium: Electronic Resource
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