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  • 1990-1994  (6)
Source
Material
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    Detection ofChlamydia trachomatis in clinical specimens by the polymerase chain reaction (1990)
    Springer
    European journal of clinical microbiology & infectious diseases 9 (1990), S. 864-868 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Sequences derived from the endogenous plasmid ofChlamydia trachomatis and from the genes coding for ribosomal 16S RNA ofChlamydia psittaci were used as primers and oligonucleotide probes for detection of chlamydiae by the polymerase chain reaction. The endogenous plasmid primers generated specific amplified products of 517 bp with all knownChlamydia trachomatis serovars. No specific products ofChlamydia psittaci andChlamydia pneumoniae could be detected using these primers. With the rRNA primers specific amplified products of 208 bp were generated withChlamydia psittaci, Chlamydia trachomatis andChlamydia pneumoniae. No specific amplified products were detected with DNA isolated from a variety of microorganisms from the urogenital and the respiratory tract. Of 156 clinical specimens used for evaluation of the polymerase chain reaction, 26 were found to be positive forChlamydia trachomatis on culture. All 26 culture positive samples were also found to be positive forChalmydia trachomatis DNA by the polymerase chain reaction with both primer sets. Two culture negative samples were also found to be positive by this technique. The polymerase chain reaction thus seems to be a sensitive and reliable method for detection ofChlamydia trachomatis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01967500
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Use of the polymerase chain reaction to study the relationship between human papillomavirus infections and cervical cancer (1991)
    Springer
    European journal of clinical microbiology & infectious diseases 10 (1991), S. 714-727 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Although it is now evident that human papillomaviruses (HPV) are strongly associated with cervical cancer, their etiological role in the oncogenesis of this disease is still unknown. However, HPV screening may identify women at risk of acquiring this disease. With the recent development of the polymerase chain reaction (PCR), it has become possible to detect small numbers of human papillomavirus genomes in clinical samples. The sensitivity and specificity of this technique, together with the possibility of performing the test on crude cervical scrapes, makes PCR the method of choice for screening. In this paper, data on the detection of human papillomavirus by PCR are presented and the applicability of this technique for the screening of human papillomavirus genotypes is evaluated. The question arises whether screening for diagnostic purposes must include all the human papillomavirus types associated with infections of the genital tract or only those which are strongly associated with cervical cancer (HPV 16 and HPV 18). It is proposed that an international council must be created that is responsible for standardised epidemiological screening strategies and follow-up programmes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01972496
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    (Anti)hydrogen recombination studies in a nested Penning trap (1993)
    Springer
    Hyperfine interactions 76 (1993), S. 181-188 
    Details
    ISSN: 1572-9540
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Extremely cold antiprotons, stored in a Penning trap at 4 K, open the way toward the production and study of cold antihydrogen. We have begun experimentally investigating the possibility to recombine cold positrons and antiprotons within nested Penning traps. Trap potentials are adjusted to allow cold trapped protons (and positive helium ions) to pass through cold trapped electrons. Electrons, protons and ions are counted by ejecting them to a cold channel plate and by nondestructive radiofrequency techniques. The effect of the space charge of one trapped species upon another trapped species passing through is clearly observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02316717
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    A single trapped antiproton and antiprotons for antihydrogen production (1993)
    Springer
    Hyperfine interactions 81 (1993), S. 5-14 
    Details
    ISSN: 1572-9540
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract During the last several years, our TRAP collaboration has pioneered techniques for slowing, trapping, cooling and indefinitely storing antiprotons to energies more than 1010 times lower than previously possible. The radio signal from a single trapped antiproton is now being used for precision measurements. Many cold antiprotons are “stacked” as another important step toward the eventual production of antihydrogen, and positrons have been trapped in vacuum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00567246
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Extremely cold antiprotons for antihydrogen production (1993)
    Springer
    Hyperfine interactions 76 (1993), S. 81-93 
    Details
    ISSN: 1572-9540
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The possibility to produce, trap and study antihydrogen atoms rests upon the recent availability of extremely cold antiprotons in a Penning trap. Over the last five years, our TRAP Collaboration has slowed, cooled and stored antiprotons at energies 1010 lower than was previously possible. The storage time exceeds 3.4 months despite the extremely low energy, which corresponds to 4.2 K in temperature units. The first example of measurements which become possible with extremely cold antiprotons is a comparison of the antiproton inertial masses which shows they are the same to a fractional accuracy of 4×10−8. (This is 1000 times more accurate than previous comparisons and large additional increases in accuracy are anticipated.) To increase the number of trapped antiprotons available for antihydrogen production, we have demonstrated that we can accumulate or “stack” antiprotons cooled from successive pulsed injections into our trap.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02316708
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    The magnetic moment of the antiproton (1993)
    Springer
    Hyperfine interactions 76 (1993), S. 379-380 
    Details
    ISSN: 1572-9540
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A scheme is proposed with which it may be possible to utilize extremely cold antiprotons in a Penning trap to measure the magnetic moment of an antiproton.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02316738
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    Paper (German National Licenses)
    Fulltext
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