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  • 1
    Electronic Resource
    Electronic Resource
    Analysis of length and surface area of each segment of the large intestine according to age, sex and physique (1992)
    Springer
    Surgical and radiologic anatomy 14 (1992), S. 251-257 
    Details
    ISSN: 1279-8517
    Keywords: Length of the large intestine ; Diameter of the large intestine ; Size of the large intestine ; Barium enema examination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé La longueur, le diamètre et la surface développée de chacun des six segments du colon ont été mesurés sur une série de 920 lavements barytés pratiqués chez des patients Japonais. Le colon transverse est le segment le plus long et le plus étendu en surface, suivi par le colon sigmoïde. Le diamètre du colon ascendant est le plus important, tandis que ceux du colon descendant et du sigmoïde sont les plus étroits. Des différences de taille du colon en fonction du sexe ont été observées. La longueur et la surface de la totalité du colon étaient toutes deux moins importantes chez les hommes que chez les femmes. Les longueurs du caecum, du colon ascendant, du colon transverse et du rectum, sont également moins importantes chez les hommes que chez les femmes. Les diamètres du colon descendant, du colon sigmoïde et du rectum sont plus importants chez les hommes que chez les femmes. La surface développée du colon ascendant et du colon transverse est moins étendue chez les hommes que chez les femmes, tandis que le total des surfaces du colon descendant, du colon sigmoïde et du rectum, est plus important chez les hommes que chez les femmes. La longueur totale du colon tend à augmenter avec l'âge. La longueur et la surface de l'ensemble du colon a également tendance à augmenter chez les femmes avec importance du morphotype.
    Notes: Summary Length, diameter and surface area of each of 6 segments of the large intestine were determined and calculated in 920 Japanese patients who underwent barium enema. Of the length and surface area measurements obtained, those of the transverse colon were the largest, followed by those of the sigmoid colon. The diameter of the ascending colon was the largest, while those of the descending colon and sigmoid colon were the smallest. There were various sex differences in size of the large intestine. Length and surface area of the entire large intestine in males were shorter and smaller respectively than those in females. Lengths of the cecum, ascending colon, transverse colon and rectum in males were shorter than those in females. Diameters of the descending colon, sigmoid colon and rectum in males were larger than those in females. Total surface areas of the ascending colon and transverse colon in males were smaller than those in females, while total surface areas of the descending colon, sigmoid colon and rectum in males were larger than those in females. Length of the entire large intestine tended to be increased with age. Length and surface area of the entire large intestine tended to be increased with an increase in physical dimensions in females.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01794949
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  • 2
    Electronic Resource
    Electronic Resource
    High levels of erythrocyte aldose reductase and diabetic retinopathy in NIDDM patients (1994)
    Springer
    Diabetologia 37 (1994), S. 328-330 
    Details
    ISSN: 1432-0428
    Keywords: Aldose reductase ; diabetic retinopathy ; erythrocyte
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Erythrocyte aldose reductase was determined in 90 NIDDM patients by a two-site ELISA using recombinant human aldose reductase. The level of aldose reductase did not correlate with age, duration of diabetes, fasting blood glucose and HbA1cof the patients. Among 38 patients with diabetes for more than 10 years, aldose reductase in those with retinopathy (including non-proliferative and proliferative) was significantly higher than in those without, while no difference in the means of the average HbA1c, maximum and minimum blood pressure levels was observed between the two groups. The results indicate that the level of aldose reductase in the erythrocyte of diabetic patients is associated with the presence of retinopathy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00398062
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  • 3
    Electronic Resource
    Electronic Resource
    High levels of erythrocyte aldose reductase and diabetic retinopathy in NIDDM patients (1994)
    Springer
    Diabetologia 37 (1994), S. 328-330 
    Details
    ISSN: 1432-0428
    Keywords: Key words Aldose reductase, diabetic retinopathy, erythrocyte.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Erythrocyte aldose reductase was determined in 90 NIDDM patients by a two-site ELISA using recombinant human aldose reductase. The level of aldose reductase did not correlate with age, duration of diabetes, fasting blood glucose and HbA1c of the patients. Among 38 patients with diabetes for more than 10 years, aldose reductase in those with retinopathy (including non-proliferative and proliferative) was significantly higher than in those without, while no difference in the means of the average HbA1c, maximum and minimum blood pressure levels was observed between the two groups. The results indicate that the level of aldose reductase in the erythrocyte of diabetic patients is associated with the presence of retinopathy. [Diabetologia (1994) 37: 328–330]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00398062
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  • 4
    Electronic Resource
    Electronic Resource
    Lack of association of the insulin gene region with Type 1 (insulin-dependent) diabetes mellitus in Japanese subjects (1994)
    Springer
    Diabetologia 37 (1994), S. 210-213 
    Details
    ISSN: 1432-0428
    Keywords: Key words Insulin gene, polymorphism, Type 1 (insulin-dependent) diabetes mellitus, Japanese, susceptibility.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Although the insulin gene region is implicated in susceptibility to Type 1 (insulin-dependent) diabetes mellitus in Caucasians, significance of this region to Type 1 diabetes in Japanese remains unclear because the class 1 alleles (shorter insertion) of the variable number of tandem repeat in the 5′ region of the insulin gene are predominant in both diabetic and non-diabetic subjects. The 5′ insulin gene polymorphism was analysed in 75 Japanese patients and 69 control subjects with a precise method using PvuII and a polymorphism specific probe, which enabled us to divide class 1 alleles into four subclasses. Allelic frequencies were not significantly different between Type 1 diabetic patients and control subjects. The polymorphism in the 3′ untranslated region of the insulin gene (1127/ PstI) was also analysed and found to be tightly linked to the 5′ insulin gene polymorphism, and thus was not associated with diabetes. Interaction between HLA-DR and the insulin gene region, which was reported in the French study, was not observed in Japanese. These results suggest that the insulin gene region is not a valuable genetic risk factor for Type 1 diabetes in Japanese. [Diabetologia (1994) 37: 210–213]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001250050095
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  • 5
    Electronic Resource
    Electronic Resource
    Pigments of Rubrobacter radiotolerans (1994)
    Springer
    Archives of microbiology 162 (1994), S. 414-421 
    Details
    ISSN: 1432-072X
    Keywords: Carotenoid ; Bacterioruberin ; Red pigment ; Radiotolerance ; Rubrobacter radiotolerans
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The highly radioresistant Rubrobacter radiotolerans, contains red pigments. Since the pigments could not be extracted by usual methods, a new method was developed in which the pigments were extracted with organic solvents after addition of 10 N KOH to the intact cells, followed by neutralization. These pigments were also extracted after treatment with achromopeptidase, but not with lysozyme. The extracted pigments separated into two main spots by TLC (48.6% and 22.6%), and were confirmed to be carotenoids by chemical tests. The two major pigments had 13 conjugated double bonds as determined from the main maximum wavelength of the light absorption spectra. Their molecular weights were determined to be 740 and 722 by mass spectrometry. The mass spectra of their TMS-derivatives revealed that they contained four and three tertiary OH groups, respectively. Confirming their identical light and IR spectra, these pigments were determined to be bacterioruberin and monoanhydrobacterioruberin, respectively, the characteristic carotenoids of halophilic bacteria. The existence of these pigments in bacteria other than halobacteria provides interesting new evidence on the distribution of these compounds.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00282106
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  • 6
    Electronic Resource
    Electronic Resource
    Pigments of Rubrobacter radiotolerans (1994)
    Springer
    Archives of microbiology 162 (1994), S. 414-421 
    Details
    ISSN: 1432-072X
    Keywords: Key words     Carotenoid ; Bacterioruberin ; Red pigment ; Radiotolerance ; Rubrobacter radiotolerans
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract      The highly radioresistant Rubrobacter radiotolerans, contains red pigments. Since the pigments could not be extracted by usual methods, a new method was developed in which the pigments were extracted with organic solvents after addition of 10 N KOH to the intact cells, followed by neutralization. These pigments were also extracted after treatment with achromopeptidase, but not with lysozyme. The extracted pigments separated into two main spots by TLC (48.6% and 22.6%), and were confirmed to be carotenoids by chemical tests. The two major pigments had 13 conjugated double bonds as determined from the main maximum wavelength of the light absorption spectra. Their molecular weights were determined to be 740 and 722 by mass spectrometry. The mass spectra of their TMS-derivatives revealed that they contained four and three tertiary OH groups, respectively. Confirming their identical light and IR spectra, these pigments were determined to be bacterioruberin and monoanhydrobacterioruberin, respectively, the characteristic carotenoids of halophilic bacteria. The existence of these pigments in bacteria other than halobacteria provides interesting new evidence on the distribution of these compounds.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002030050159
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  • 7
    Electronic Resource
    Electronic Resource
    Effect of fluoride on root resorption caused by mechanical injuries of the periodontal soft tissues in rats (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Dental traumatology 10 (1994), S. 0 
    Details
    ISSN: 1600-0595
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract The present study was carried out to investigate histologically and histometrically the effect of fluoride on root resorption induced by mechanical injuries of the periodontal soft tissues in rats. Resorption lacuna in the root surface of the molar in animals given both mechanical injuries and fluoride administration was significantly smaller in length and area than that in animals given only mechanical injuries. Moreover, resorption lacuna in the former animals contained fewer odontoclasts than that in the latter. The results of the present study might suggest that the administration of fluoride suppressed root resorption induced by mechanical injuries of the periodontal soft tissues.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-9657.1994.tb00071.x
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  • 8
    Electronic Resource
    Electronic Resource
    Histopathologic prognostic factors in stage IIb cervical carcinoma treated with radical hysterectomy and pelvic-node dissection — an analysis with mathematical statistics (1993)
    238 Main Street, Cambridge, Massachusetts 02142, USA : Blackwell Scientific Publications
    International journal of gynecological cancer 3 (1993), S. 0 
    Details
    ISSN: 1525-1438
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Of 107 patients with stage IIb cervical cancer who underwent laparotomy, 82 (77%) could be treated with radical hysterectomy (RAH) and pelvic-node dissection (PND). The remaining 25 patients were unsuitable for radical surgery because of para-aortic lymph node metastases, direct cancer invasion into the bladder muscle, and/or fixed enlarged pelvic lymph nodes (PLN): Such patients were treated with radiation therapy after laparotomy. Fifty-nine of RAH patients were given postoperative pelvic radiation because they had PLN metastases, parametrial invasion, and/or full thickness cervical stromal invasion. The overall 5-year survival of the patients undergoing RAH was significantly better than that of those who could not be treated with RAH (P 〈 0.001). In the RAH patients, parametrial invasion, which clinically defines stage IIb, was found only in 45%. Univariate analysis of histopathologic prognostic factors revealed that PLN metastasis, parametrial invasion, adenocarcinoma, and lymph-vascular space invasion significantly affected survival of the RAH patients (P 〈 0.05). Multivariate analysis using Cox’s proportional hazards regression model, however, selected only PLN metastasis as a strong prognostic factor (P 〈 0.001). Concerning PLN metastasis patients with two or more positive nodal groups vs. 49%, P 〈 0.0001). The logistic regression analysis revealed that tumor diameter, parametrial invasion and lymph-vascular space invasion were independently correlated with PLN metastases in two or more nodal groups. The present data suggest that (i) the patients with massive pelvic extension of cancer cannot be cured by radiation therapy alone, (ii) the strong determinant of the prognosis of the patients undergoing RAH and PND is PLN metastasis. Therefore, for these patients with poor prognosic factors, other treatment modalities should be considered. From the present study it seems that planning RAH and PND for patients with stage IIb disease might make it possible to select poor prognostic subgroups, who have extra cervical extension or PLN metastases in two or more groups, and be useful in individualizing treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1525-1438.1993.03040219.x
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  • 9
    Electronic Resource
    Electronic Resource
    Treatment of patients with advanced ovarian carcinoma with massive pleural effusions (1991)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of gynecological cancer 1 (1991), S. 0 
    Details
    ISSN: 1525-1438
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract. Imachi M, Tsukamoto N, Shimamoto T, Kamura T, Saito T, Nakano H. Treatment of patients with advanced ovarian carcinoma with massive pleural effusions. Int J Gynecol Cancer 1991; 1: 263–267.Twelve patients with advanced ovarian carcinoma who had massive pleural effusions were treated between 1985 and 1989. Clinical stages of these patients were stage IIa, 1 and stage IV, 11. Histologic diagnoses were six serous adenocarcinomas, three endometrioid carcinomas, one mucinous adenocarcinoma, one clear cell carcinoma, and one squamous cell carcinoma. Massive pleural effusions were noted in the chest roentgenograms in all patients. Eight patients had effusions in pleural cavity, and four in both. The volumes of fluid removed from the pleural cavities ranged from 440 to 3650 ml, with a mean of 1905 ml. Eleven patients (92%) had malignant cells in their pleural effusions. Before surgery, all patients received thoracocentesis, and nine of them underwent continuous drainage by thoracic tubes. Eleven patients were given cis-platinum-containing chemotherapy after operation. Seven patients died of disease within two years. However, four patients underwent second-look operation and showed no evidence of residual disease. Malignant pleural effusions in ovarian carcinoma showed a good response to cis-platinum containing systematic chemotherapy. From the above results, it is concluded that under the drainage of pleural effusions debulking surgery followed by systematic chemotherapy is useful for patients with advanced ovarian carcinomas and massive pleural effusions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1525-1438.1991.tb00053.x
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  • 10
    Electronic Resource
    Electronic Resource
    Endometrial carcinoma in women aged 40 years or younger: a Japanese experience (1993)
    238 Main Street, Cambridge, Massachusetts 02142, USA : Blackwell Scientific Publications
    International journal of gynecological cancer 3 (1993), S. 0 
    Details
    ISSN: 1525-1438
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We report on the clinical and pathologic findings in 17 cases of endometrial carcinoma in Japanese women aged 40 years or younger. Age of the patients ranged from 16 to 40 years, with a median of 35 years. Nine of 17 tumors (52.9%) were stage I or II (FIGO 1988) but 8 (47.1%) were stage III. Four of the 8 patients with stage III disease had pelvic lymph node metastases and one also had para-aortic lymph node metastasis. One patient had metastasis to the ovary and peritoneal cytology was positive in 4 patients. Histologically, 13 of these 17 patients had endometrioid adenocarcinoma, 3 had adenoacanthoma and 1 had an undifferentiated carcinoma. Ten were well differentiated tumors (G1), 3 were moderately differentiated tumors (G2), and 4 were poorly differentiated tumors (G3). Nine of 17 (52.9%) showed deep myometrial invasion (more than a half of the myometrium) and 5 of 17 (29.4%) demonstrated lymphatic/vascular space invasion. Pelvic and para-aortic lymph node metastases were seen in 4 of 15 (26.7%) and 1 of 15 (6.7%), respectively. Two of these 17 patients died of disease in a relatively short follow-up period. In our experience there is no difference in the survival rates between patients aged 40 years or younger and those over 40 years.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1525-1438.1993.03030147.x
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