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  • 1
    ISSN: 0942-0940
    Keywords: Dynamic CT ; xenon CT ; ischaemic cerebrovascular disease ; reversibility of ischaemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Flow studies using dynamic CT and xenon (Xe) CT were carried out in 25 patients with ischaemic stroke in the territory of the middle cerebral artery to define the clinical characteristics of cerebral ischaemia at a chronic stage. The parameter of peak height/mean transit time (PH/MTT) obtained from dynamic CT can provide an accurate index for blood circulation in the cerebral vascular bed. Xe CT measurements revealed various kinds of ischaemia around the infarction even in the chronic stages. In mild ischaemia of more than 30ml/100g/min, reduction of cerebral blood flow (CBF) was well correlated to the PH/MTT. However, in severe ischaemia between 20 and 30 ml/100 g/ min, changes of CBF were no longer correlated with the PH/MTT. There were cases showing severe reduction of CBF but which showed sufficient blood circulation (moderate value of PH/MTT). Mild reductions of CBF in parallel with decreased blood supply were often found in the peri-infarct area of infarctions in the centrum semiovale. On the other hand, infarctions in the cortico-subcortical region showed severe ischaemia, in even where blood circulation was relatively well sustained.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 21 (1991), S. 0 
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: To investigate the relationships between allergen inhalation challenge and other diagnostic procedures, inhalation challenge with house dust (HD) allergen, intradermal skin tests with HD allergen, inhalation challenge with methacholine and circulating HD allergen-specific IgE levels were examined in 104 patients with bronchial asthma. Using the single exposure method, allergen inhalation challenge was performed. Forty-three patients had positive bronchial responses to allergen and 61 patients had negative bronchial responses. With serially diluted HD allergen (10-3 to 10-6, w/v), skin-test sensitivity was expressed as the highest dilution required to produce a weal of more than 9.9 mm. With the continuous exposure method, bronchial responsiveness to methacholine was evaluated as the number of units of inhaled methacholine (PD35-Grs) from the start to the point at which Grs had decreased by 35% from its baseline value. The level of circulating HD allergen-specific IgE was measured with the Phadebas. RAST system and the results were assessed as a RAST score. Using discriminate analysis, in which the independent variables were skin-test sensitivity. PD35-Grs and the RAST score, only in 30% of all patients was bronchial responsiveness to inhaled HD allergen predictable. Therefore, we suggest that inhalation challenge with allergen is an essential test for determining the role of a specific allergen in airways at present.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 69 (1991), S. 4580-4582 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Polycrystalline films of nonthermodynamical garnet Bi3Fe5O12 were synthesized by direct epitaxial growth from the vapor phase. Polycrystalline thin layers of various kinds of thermodynamical garnets prepared on fused quartz substrates were employed as the substrate materials. The saturation magnetization of the film grown onto the polycrystalline GGG layer was 140 mT at 5 K. The films showed quite large magneto-optical effects. In the film on the GGG layer, the Faraday rotation angle at a wavelength of 633 nm was −5.5 deg/μm and the magneto-optical Kerr rotation angle at 455 nm was −0.9°.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 67 (1990), S. 4944-4946 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Nonthermodynamical garnet Bi3Fe5O12 was synthesized by direct epitaxial growth via vapor phase using a reactive ion beam sputtering technique. The lattice constant was 12.631 A(ring). The saturation magnetization of the film grown onto a substrate (a=12.495 A(ring)) was 1500 G at room temperature. The uniaxial anisotropy energy was +7.2×104 erg/cm3. The conversion electron Mössbauer spectroscopy measurement indicates that the internal fields of 24d and 16a sites in the nearly lattice-matched film were 420 and 490 kOe, respectively. The internal field of the 24d site was larger by 30 kOe than that in YIG. The angle between the direction of the internal field and the film normal was 34.8°.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    European journal of plastic surgery 14 (1991), S. 274-279 
    ISSN: 1435-0130
    Keywords: Bone graft ; Vascularized bone graft ; Reconstruction of tibia ; Pedicled vascularized fibula graft
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Free vascularized fibula grafts have been used to reconstruct long tibial bone defects since Taylor's report in 1975. A pedicled vascularized fibula graft is also useful for small bone defects or pseudoarthrosis because of its excellent vascularity. The pedicled vascularized fibula transfer does not need the microvascular anastomosis and can be performed in much less time. It can be distally or proximally pedicled, depending on the site of the bone defect. A proximally or distally pedicled vascularized fibula with or without a monitoring flap was transferred in five cases of small bone defects and pseudoarthrosis of the tibia. In all 5 cases, the postoperative course was uneventful and good bony union was obtained.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    European journal of plastic surgery 15 (1992), S. 151-153 
    ISSN: 1435-0130
    Keywords: Cleft lip and palate ; Craniosynostosis ; Oxycephaly ; Scaphocephaly
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Although syndromic cleft lip and palate is occasionally associated with other anomalies, even with craniosynostosis, non-syndromic cleft lip and palate is rarely seen with craniosynostosis. The morphogenesis of these two anomalies seems different, and combined cases are interesting to report. Two rare cases of the association of non-syndromic cleft lip and palate and craniosynostosis (one oxycephaly and the other scaphocephaly) which were operated on with a follow-up of 10 years and 2 years are described.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0584
    Keywords: Aging ; Erythrocytes ; Platelet-activating factor ; Acyltransferases ; Membrane fluidity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Platelet-activating factor acetylhydrolase is known to degrade oxidatively fragmented phospholipids which are similar in structure to platelet-activating factor. We examined changes of acetylhydrolase activity during in vivo aging of human erythrocytes and tried to assess its role in maintaining the membrane properties of erythrocytes. Higher-density erythrocytes are enriched with older cells. Erythrocytes obtained from seven healthy colleagues were separated into four density fractions by centrifugation in discontinuous Percoll density gradients. Both membrane and cytosolic acetylhydrolase decreased with increasing erythrocyte density. Membrane and cytosolic acetylhydrolase activities in the lightest fraction were 2.0±1.0 (SD) nkat/g protein and 362±58 pkat/g protein, respectivley, and these values were significantly higher than those in the densest fraction: 1.3±0.7 nkat/g protein and 286±70 pkat/g protein, respectively. Membrane acyltransferase activity also decreased with red cell density and the average values in the lightest and densest fractions were 51.2±23.6 and 27.0±20.2 μkat/g protein, respectively. Generation of thiobarbituric acid-reactive substances induced byt-butyl hydroperoxide treatment decreased with increasing cell density, and the inhibition of acetylhydrolase with diisopropylfluorophosphate resulted in enhanced peroxide-induced lipid oxidation, particularly in lower-density fractions. There was no significant change in basal levels of thiobarbituric acid-reactive substances in red cell membrane. Membrane fluidity was evaluated by fluorescence recovery after photobleaching and it decreased as erythrocyte density increased. We conclude that the activity of the deacylation/reacylation cycle maintained by acetylhydrolase and acyltransferase is gradually reduced during in vivo aging of erythrocytes. This may be connected with decreases of polyunsaturated fatty acids and membrane fluidity in old eryhtrocytes.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1420-9071
    Keywords: Frog skeletal single fibres ; phenylglyoxal (PGO) ; E-C coupling ; solubilization ; PGO-binding protein (PGO-protein) ; monoclonal antibody ; electrometrin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The excitation-contraction (E-C) coupling process in single twitch fibres from frog toe muscle was inhibited selectively by phenylglyoxal (PGO), a specific guanidyl modifying reagent. A new protein (31.5 kDa), which has PGO-binding ability and seems to play a key role in the E-C coupling process, was solubilized from transverse tubule membrane-junctional sarcoplasmic reticulum complexes (TTM-JSR) of frog skeletal muscles, using14C-PGO. The monoclonal antibody against this protein applied extracellularly inhibited the E-C coupling process of the single fibres. This protein appears to constitute the very first step of input for E-C coupling. It is considered to behave as an indispensable part of an ‘electrometer’ to measure membrane potentials. Therefore, the name ‘electrometrin’ is suggested for the new protein.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 49 (1993), S. 711-717 
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: FTIR spectroscopy and X-ray photoelectron spectroscopy (XPS) were applied to examine the slip-reducing mechanism of polypropylene-laminated films. The relationship between the slip and the amount of lubricants was established on the basis of quantitative analysis of lubricants on the cast and laminated polypropylene film surfaces. The results suggested that erucic amide used as a lubricant for the cast film migrated from the film surface into the adhesive layer, probably due to intermolecular interactions (hydrogen bonds) with an isocyanurate-ether-polyol used as an adhesive for laminating the films. This enabled us to understand the slip-reducing mechanism in the laminated films. © 1993 John Wiley & Sons, Inc.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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