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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Biochemistry 31 (1992), S. 5856-5860 
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Macromolecules 24 (1991), S. 3522-3527 
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Macromolecules 26 (1993), S. 6391-6396 
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Macromolecules 26 (1993), S. 6447-6454 
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Langmuir 10 (1994), S. 4153-4156 
    ISSN: 1520-5827
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Immunology 10 (1992), S. 617-644 
    ISSN: 0732-0582
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1619-7089
    Keywords: Immunoscintigraphy ; Intraoperative immunoscintimetry ; Gamma probe ; Technetium-99m carcinoembryonic antigen-specific antibody ; Colorectal neoplasm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The immunoscintigraphic detection of tumour foci 〈 1 cm in diameter fails even with single photon emission tomography (SPET) owing to low contrast against background activity. In an attempt to improve detection of macroscopically invisible tumour spread, intraoperative scintimetry (IOSM) with a hand-held gamma-probe was performed in addition to SPET 24–30 and 41–48 h after injection of the technetium-99m carcinoembryonic antigen (CEA MoA) on 12 patients with colorectal carcinoma and 3 patients with different neoplastic and inflammatory diseases. Tumour specimens were measured in vitro in a gamma well counter. For comparison, the presence and amount of CEA in the tumour cells were evaluated immunohistochemically. After modification, the gamma-probe originally designed for iodine-131 was 20 times more sensitive; activities of 99Tc located close to the collimator hole were measured with absolute sensitivity of 100 cps = 2.5 kBq 99mTc. The unfavourably high background activity affected both the in vitro and in vivo analysis: SPET results had been considered positive in 8 of 15 cases. In vitro tumour/non-tumour (t/nt) ratios 〉 2.0 were found in 4 cases. In vivo IOSM resulted in t/nt ratios 〉2.0 in only 3 patients. In most cases, there was no coincidence of elevated t/nt ratios from the different methods. A correlation was derived between positive immunoscintimetric in vitro findings and immunohistochemically proven interstitial localization of CEA in tumor cells. In conclusion, the measurement technique of IOSM seems adequate, but clinical success will depend on a more specific enrichment of MoA in tumour tissue. Future in vivo studies should be performed mainly in cases with a positive immunohistochemistry (interstitial CEA localization) result for the primary tumour.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1459
    Keywords: Mulitple sclerosis ; Adrenocorticotropin ; Dexamethasone ; Glucocorticoid ; Auditory brain-stem response
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Auditory brain-stem responses (ABRs) were compared in two groups of multiple sclerosis (MS) patients receiving standard treatment with adrenocorticotropin (ACTH) and with dexamethasone (DEX). ABRs were recorded prior to treatment, on the lst and 8th day of therapy, and 21 days after the hormonal treatment had been discontinued. ABRs in MS patients were within the normal range of variability. Latencies of ABR components increased with increasing rate of presentation, and with decreasing intensity of the click stimuli. Changes in ABRs displayed a consistent pattern in patients treated with ACTH, but showed less coherence after DEX. In ACTH treated patients' latencies of the late ABR waves V and Vn were prolonged after clicks of high intensity, and reduced following clicks of low intensity resulting in a decreased slope of the latency-intensity function of these ABR waves. This pattern became most prominent in the recordings after the treatment had been discontinued, and could reflect an improved transmission across both afferent excitatory and recurrent inhibitory synapses in the auditory pathways. The findings indicate that — besides a common anti-inflammatory action — therapies with ACTH and DEX differ with regard to their influence on central nervous functioning.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric radiology 23 (1993), S. 355-356 
    ISSN: 1432-1998
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 3-year-old boy with a radiographic finding of an isolated invaginated Meckel's diverticulum is presented. The abnormality simulates a polypoid filling defect in the distal small bowel on barium examination. This particular manifestation of Meckel's diverticulum is very rare and has been reported only once previously. This article re-emphasizes the need to think about this possibility when a polypoid filling defect is seen in the distal small bowel. At the time laparotomy was performed, the abnormality had progressed into a triple intussusception, a rare surgical finding.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 379 (1994), S. 70-75 
    ISSN: 1435-2451
    Keywords: Ulna ; Radius ; Blood vessels ; Bone graft ; Pseudarthrosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Ulna und Radius haben ein zusammenhängendes arterielles Versorgungssystem. Das proximale Viertel der Ulna erhält Zuflüsse aus der A. ulnaris, der A. recurrens ulnaris and der A. interossea recurrens. Ihre Diaphyse wird hauptsächlich aus der A. interossea anterior versorgt. Die arterielle Versorgung des distalen Fünftels erfolgt durch Endäste der A. interossea anterior mit Unterstützung durch die A. ulnaris. Die A. nutricia stammt meist aus der A. interossea anterior, tritt oberhalb der Ulnamitte in die Corticalis and zieht nach proximal. Intramedullär hat sie einen aufsteigenden und einen schwächeren absteigenden Ast. Das proximale Radiusviertel wird durch einen R. periostalis versorgt, der zumeist aus der A. interossea communis stammt. Weiterhin wird das proximale Fünftel durch Rr. periostaes aus der A. ulnaris und der A. interossea recurrens versorgt. Die Diaphyse erhält Zuflüsse aus der A. interossea anterior. Das distale Fünftel wird hauptsachlich durch Endäste der A. interossea anterior versorgt, unterstützt durch die A. radialis und die A. ulnaris. Die A. nutricia aus der A. interossea anterior zieht ab knapp 40% der Radiuslänge in der Corticalis nach proximal und hat einen stärkeren aufsteigenden und einen schwächeren absteigenden Ast. Die A. interossea anterior ist das Hauptgefäß für die Versorgung beider Unterarmknochen. Sic gilt es sowohl bei der Transplantation als auch bei der operativen Rekonstruktion zu beachten. Zur Schonung der Rr. periostales sind bei der Osteosynthese sog. LC-DC-Platten empfehlenswert. Beim Heben eines vaskularisierten Knochentransplantates ist auch auf die arterielle Versorgung der verbleibenden Knochenanteile zu achten; gleichwohl sind durch die Angioarchitektur verschiedene Möglichkeiten der Transplantation gegeben.
    Notes: Abstract The periosteal and endosteal blood supply of the human ulna and radius was investigated by anatomical dissection. The main artery concerned is the anterior interosseous artery. It supplies the diaphysis of ulna and radius; its branches feed the distal one-fourths of both the ulna and the radius. The proximal one-fourth of the ulna is supplied by the ulnar artery, the ulnar recurrent artery and the recurrent interosseous artery. Periosteal branches of the common interosseous artery, the ulnar artery and the recurrent interosseous artery supply the proximal one-fourth of the radius. In both bones the main branch of the nutrient artery has an ascending course. The anterior interosseous artery, as the main artery of the periosteal and endosteal supply of the human ulna and radius, is important in transplantation and reconstruction, especially with a view to reducing the rate of pseudarthrosis. When osteosynthesis is planned so-called LC-DC plates should be chosen to preserve the periosteal branches. When a vascularized bone graft is taken from the forearm the vascularization of the remaining bones has to be considered. The vascularity of this area allows various options in grafting.
    Type of Medium: Electronic Resource
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