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  • 1
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A model is described of acute inflammation in the pleural cavity of rats using calcium pyrophosphate as the irritant. This model would seem to simulate the pseudogout syndrome. It has been shown to be acute in onset, dominated by polymorphonuclear cells, complement independent. The advantage of the model is that volume of exudate, numbers and types of cells may be quantitated. Prostaglandins and cyclic AMP have been measured in the migrating cells. The significance of these findings has been discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Archives of microbiology 162 (1994), S. 249-254 
    ISSN: 1432-072X
    Keywords: Siderophore ; Iron-uptake ; Acinetobacter baumannii ; Acinetobactin ; ω-N-Hydroxyhistamine 2,3-Dihydroxybenzoic acid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A novel siderophore, called acinetobactin, with both catecholate and hydroxamate functional groups was isolated from low-iron cultures of Acinetobacter baumannii ATCC 19606. The structure was elucidated by chemical degradation, fast-atom bombardment mass spectrometry and 1H and 13C NMR spectroscopy. Acinetobactin was composed of ω-N-hydroxyhistamine, threonine and 2,3-dihydroxybenzoic acid, the last two components forming an oxazoline ring. Acinetobactin was structurally related to anguibactin, a plasmid-encoded siderophore of Vibrio anguillarum. The only difference was that acinetobactin possessed an oxazoline ring instead of a thiazoline ring. Four of 12 other clinical A. baumannii strains examined produced acinetobactin, indicative of strain-to-strain variation in the ability to produce acinetobactin. In addition, a relatively small amount of acinetobactin was also detected in A. haemolyticus ATCC 17906.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Archives of microbiology 162 (1994), S. 249-254 
    ISSN: 1432-072X
    Keywords: Key words     Siderophore ; Iron-uptake ; Acinetobacter baumannii ; Acinetobactin ; ω-N-Hydroxyhistamine ; 2 ; 3-Dihydroxybenzoic acid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract      A novel siderophore, called acinetobactin, with both catecholate and hydroxamate functional groups was isolated from low-iron cultures of Acinetobacter baumannii ATCC 19606. The structure was elucidated by chemical degradation, fast-atom bombardment mass spectrometry and 1H and 13C NMR spectroscopy. Acinetobactin was composed of ω-N-hydroxyhistamine, threonine and 2,3-dihydr ybenzoic acid, the last two components forming an oxazoline ring. Acinetobactin was structurally related to anguibactin, a plasmid-encoded siderophore of Vibrio anguillarum. The only difference was that acinetobactin possessed an oxazoline ring instead of a thiazoline ring. Four of 12 other clinical A. baumannii strains examined produced acinetobactin, indicative of strain-to-strain variation in the ability to produce acinetobactin. In addition, a relatively small amount of acinetobactin w as also detected in A. haemolyticus ATCC 17906.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1076
    Keywords: Hypergalactosaemia ; Portal-hepatic venous shunt ; Hepatic arterio-venous shunt ; Portosystemic shunting ; Newborn screening
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Hypergalactosaemia was discovered in a newborn girl during routine metabolic screening. Hereditary enzyme deficiency was ruled out. She had multiple hepatic haemangiomas with portal-hepatic venous and hepatic arterio-venous shunts. Since she showed signs of high-output heart failure due to the arterio-venous shunt, hepatic artery embolization was performed at age 3 months. A galactose tolerance test was performed before and after embolization and when the haemangioma no longer appeared on ultrasonography. Even after embolization, the level of blood galactose was abnormally elevated in the galactose tolerance test, but the blood galactose was eliminated more rapidly than before embolization. When the hepatic haemangioma was no longer detected by ultrasonography, the peak galactose level decreased. We surmise that the hypergalactosaemia was due to these shunts. In cases of hypergalactosaemia of unknown cause; liver haemangioma with portal-hepatic venous shunting should be considered as a possible cause. If a hepatic arteriovenous shunt also exists, this may contribute to the effect of the portosystemic shunting.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 65 (1994), S. 1653-1655 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Time-dependent change in the visible luminescence of porous Si immersed in HF aqueous solution was measured in a short acquisition time (5 s) with a charge coupled device detector. Under Ar+ laser light (514.5 nm) irradiation, the photoluminescence band of the porous Si shifted to shorter wavelength accompanying a reduction of the peak intensity. The result suggests that the size of the Si nanostructure is closely related to the gap energy of the porous Si.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1365-2826
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: It is not entirely clear whether or not atrial natriuretic peptide (ANP) directly inhibits vasopressin neurons in the supraoptic nucleus (SON) and paraventricular nucleus. Recently, a novel peptide, brain natriuretic peptide (BMP), which has been isolated from the brain, has been shown to have a similar action to ANP on the regulation of vasopressin release. Intracerebroventricular injection of both BNP and ANP inhibits stimulus-evoked increases of plasma vasopressin level. The present study was undertaken: 1) to investigate whether BNP affects the activity of neurons in the region of the anteroventral third ventricle (AV3V) and SON which are involved in the control of body fluid homeostasis and blood pressure regulation, 2) to reassess effects of ANP on SON neurons, and 3) to test whether BNP exerts its effects by mechanisms which are different from those of ANP. Extracellular recordings were made from 213 AV3V and 110 SON spontaneously firing neurons in the rat coronal hypothalamic slice preparation. Of the AV3V neurons tested, BNP inhibited 86 (40%) and excited 2 (1%) while 125 neurons remained unaffected. A dose-response relationship was obtained for 7 AV3V neurons at different BNP concentrations ranging from 10−11 M to 10−6 M; the firing rates of all 7 neurons decreased. The threshold concentration to evoke inhibitory responses was approximately 10−10M in the AV3V. When BNP and ANP were applied to the same neuron, most AV3V neurons which were inhibited by BNP were also inhibited by ANP and the neurons which were unaffected by BNP were also unaffected by ANP. Thus, these two peptides probably have a similar action on AV3V neurons. When BNP and angiotensin II were applied to a group of 60 neurons in the AV3V, most of the responsive neurons showed either inhibitory responses to BNP or excitatory responses to angiotensin II. Both BNP and ANP were applied to a group of 110 SON neurons: BNP (10 −7 M) inhibited 52 (75%) of 69 phasic (putative vasopressin) neurons, while BNP affected none of the 41 non-phasic (putative oxytocin) neurons. By contrast, ANP inhibited only 20 (29%) of 69 phasic neurons tested but it also had no effect on 41 non-phasic neurons tested. Our results are consistent with the suggestion that BNP is involved in the regulation of vasopressin release by acting on SON neurons and AV3V neurons.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 74 (1993), S. 809-812 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: In high-power AlGaAs window structure lasers with a window grown on facets (WGF) structure, dependence of window effects on Al content of the window layer is examined. When the Al content of the window layer is more than that of the cladding layer, the window effects are found. But, in other cases, the window effects do not occur. A calculation of a carrier leakage from the active layer to the window layer is performed. From the result, we deduce that the reduction of the window effects is caused by the carrier leakage. In the WGF laser with the confirmed window effects, a maximum output power of 350 mW is achieved and highly reliable operation under 100 mW at 50 °C beyond 10000 h is attained.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The Faraday rotation constants in a magneto-optic channel waveguide whose magnetization aligns along the direction of propagation are measured by a novel method developed by the authors. The tested sample is a lanthanum and gallium substituted yttrium iron garnet optical channel waveguide prepared by the liquid phase epitaxial and the ion milling techniques. The proposed method is more practical than the previously reported one because of determination of the parameters with one time measurement. In the previous method we needed to know the phase constant difference between the orthogonally polarized waves to determine the Faraday coefficient. Using the presented technique we successfully measure the magneto-optic coefficients in the iron garnet waveguide at the near infrared wavelengths: 1.15, 1.3, and 1.55 μm. We confirm the validity of the proposed method by comparing with other methods: the previously reported method and the Faraday modulation method conventionally used for measuring the Faraday rotation. We also demonstrate the waveguide isolator operation.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 70 (1991), S. 5000-5003 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A thermally stimulated current (TSC) has been applied to estimate the trap properties on a thin film of β-form oxotitanium phthalocyanine (β-TiOPc) dispersed in polyester. The hole trapping levels derived from the activation energies (Eas) were obtained by an initial rising method and heating rate dependence on TSC peaks. The Eas for an electric field of 2.5×103 V/cm were distributed from 0.033 eV for shallow traps to 0.42 eV for deep traps.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY : American Institute of Physics (AIP)
    Physics of Fluids 3 (1991), S. 1468-1468 
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: In binary fluid mixtures with negative separation ratio, the conduction state has a vertical concentration gradient, due to the Soret effect, which opposes the destabilizing effect of the vertical temperature gradient. The first convective states are traveling waves (TW) with a phase velocity which is much lower than that of the linear instability. Recent perturbation theory calculations and numerical simulations of this nonlinear, traveling-wave state predict that the linear concentration gradient in the conduction state is eliminated in the interior of the fluid by convective mixing, and the concentration gradient remains only in the boundary layers. It is the persistence of the concentration gradient in these boundary layers which leads to the small but nonzero wave speed. As the Rayleigh number R is increased, convective stirring of the mixture decreases the concentration boundary layers, and the TW phase speed goes continuously to zero. We report experimental studies of these nonlinear, traveling-wave states in ethanol/water mixtures in an annular geometry. The measured TW phase speed as a function of R is in excellent agreement with the theoretical predictions over the entire TW branch. The experiments also confirm that this transition to stationary convection is not hysteretic. The role of mixing and the transport of concentration in the dynamics of nonlinear fronts and pulses observed in this system will also be discussed. [Work supported by DARPA URI Contract No. N00014-86-K-0758.]
    Type of Medium: Electronic Resource
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