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  • 2005-2009  (1)
  • 1985-1989  (15)
  • 1
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 54 (1989), S. 1884-1886 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Negative transconductance is reported in a resistive gate metal-semiconductor field-effect transistor (MESFET) for the first time. The negative transconductance arises as a result of the negative differential mobility of electrons in the GaAs channel, and is adequately described by a simple equivalent circuit model. The experimental device is fabricated with a planar ion-implanted MESFET process, and shows promise as a microwave signal source for use in monolithic microwave integrated circuits.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Fluids 28 (1985), S. 1962-1967 
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The generation of millimeter wave radiation from the interaction of a rotating electron beam (2 MeV, 1 kA, 5 nsec) with an azimuthally periodic wiggler magnetic field has been studied experimentally. Calculations of the effects of the wiggler magnetic field on the single particle electron orbits are presented, together with experimental measurements of the effects of the wiggler field on the electron beam. Narrow-band radiation at power levels in excess of 200 kW has been observed at 88 and 175 GHz for wiggler fields with 6.28 and 3.14 cm periods, respectively. The radiation frequency spectra for various experimental configurations are presented, and results are compared with theoretical expectations.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Fluids 28 (1985), S. 1995-2006 
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Measurements of narrow-band (Δω/ω≤0.02) microwave emission from a tunable (7≤ω/2π≤21 GHz) Raman, free-electron laser operating in a single TE11 waveguide mode are reported. Approximately 100 kW of rf power has been observed at an electronic efficiency of 12%, and ∼1 MW of rf power has been generated at a reduced efficiency of 8%. Frequency, gain, and rf power measurements have been carried out for various values of the guide magnetic field, below, above, and near to the resonance between the cyclotron frequency of the guide magnetic field and the frequency associated with the periodic wiggler magnetic field. The results are in very good agreement with the predictions of three-dimensional free-electron laser theory.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Fluids 28 (1985), S. 1186-1192 
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Calculations show that modes resembling the free-electron laser (FEL) instability are excited when electrons move in quasicircular orbits under the combined action of a uniform axial magnetic field and an azimuthally periodic wiggler magnetic field. In the model, a thin annular ring of rotating electrons is confined in a hollow cylindrical waveguide, or between concentric cylinders comprising a coaxial waveguide, and the dispersion equations for the transverse magnetic (TMlm ) modes are derived and analyzed. Coherent radiation occurs near frequencies ω corresponding to the crossing points of the electromagnetic modes ω=ωc(l,m) and the beam modes ω=(l+N)Ω(parallel), where ωc and Ω(parallel) are the waveguide cutoff frequency and the electron cyclotron frequency, respectively, and N is the number of wiggler periods.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Fluids 28 (1985), S. 2524-2536 
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The long-time quasilinear development of the free-electron laser instability is investigated for a tenuous electron beam propagating in the z direction through a helical wiggler field B0=−Bˆ cos k0zeˆx−Bˆ sin k0zeˆy. The analysis neglects longitudinal perturbations (δφ(approximately-equal-to)0) and is based on the nonlinear Vlasov–Maxwell equations for the class of beam distributions of the form fb(z,p,t) =n0δ(Px)δ(Py)G(z,pz,t), assuming ∂/∂x=0=∂/∂y. The long-time quasilinear evolution of the system is investigated within the context of a simple "water-bag'' model in which the average distribution function G0( pz,t) =(2L)−1∫L−L dz G(z,pz,t) is assumed to have the rectangular form G0( pz,t) =[2Δ(t)]−1 for ||pz−p0(t)|| ≤Δ(t), and G0( pz,t) =0 for ||pz−p0(t)|| 〉Δ(t). Making use of the quasilinear kinetic equations, a coupled system of nonlinear equations is derived which describes the self-consistent evolution of the mean electron momentum p0(t), the momentum spread Δ(t), the amplifying wave spectrum ||Hk(t)||2, and the complex oscillation frequency ωk(t) +iγk(t).These coupled equations are solved numerically for a wide range of system parameters, assuming that the input power spectrum Pk(t=0) is flat and nonzero for a finite range of wavenumber k that overlaps with the region of k space where the initial growth rate satisfies γk(t=0) 〉0. To summarize the qualitative features of the quasilinear evolution, as the wave spectrum amplifies it is found that there is a concomitant decrease in the mean electron energy γ0(t)mc2=[m2c4+e2Bˆ2/k20 +p20(t)c2]1/2, an increase in the momentum spread Δ(t), and a downshift of the growth rate γk(t) to lower k values. After sufficient time has elapsed, the growth rate γk has downshifted sufficiently far in k space so that the region where γk 〉0 no longer overlaps the region where the initial power spectrum Pk(t=0) is nonzero. Therefore, the wave spectrum saturates, and γ0(t) and Δ(t) approach their asymptotic values.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 110 (1988), S. 1982-1983 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 110 (1988), S. 8201-8206 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 111 (1989), S. 7185-7190 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK; Malden, USA : Blackwell Science Ltd
    Scandinavian journal of immunology 62 (2005), S. 0 
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Ischemic brain injury is acute local inflammation, leading to accumulation of pro-inflammatory cytokines. Cytokines influence the recruitment of leucocytes and play a key role in the inflammatory injury processes. Recently, a number of studies have demonstrated a close relationship between brain ischemia and cytokines. Interleukin-17 (IL-17) is a newly identified T-cell-specific cytokine. In this study, we evaluated the source and the action of IL-17 over the course of cerebral ischemia in rats (Sprague-Dawley) and humans. The levels of IL-17 in the ischemic hemisphere of the human brain, which was removed at necropsy, were assayed immunohistochemically. In rats, permanent middle cerebral artery occlusion (pMCAO) was obtained by inserting nylon monofilament into the right external carotid artery, occluding the right middle cerebral artery. The expression of IL-17 mRNA in rat was assayed using oligoprobe in situ hybridization. IL-17 production by neuroglial cells was assayed by double-staining using antibody glial fibrillary acidic protein (GFAP) and antibody IL-17. Levels of IL-17 were elevated in the ischemic hemispheres of human brain compared with the opposite normal hemispheres and peaked at days 3–5 after brain ischemia. The IL-17-positive cells were found in the ischemic lesion region. IL-17 mRNA was also elevated in ischemic hemispheres of pMCAO-operated rats, which were slightly elevated after 1 h and peaked at 6 days. IL-17 and GFAP double-stained were extensive in rat ischemic hemisphere. The ischemia-induced IL-17 expression in human brain reported here for the first time was very similar to that in rat model except that the peak was slightly earlier. We found for the first time that IL-17 was involved in an intense inflammatory reaction of brain ischemic injury in human. In pMCAO-operated rats, our findings suggest that IL-17 is produced by the neuroglial cells in the brain region undergoing ischemic insult. We suggest that in additional to T cells the neuroglial cell may be another cellular origin of IL-17 in later progression of brain ischemia.
    Type of Medium: Electronic Resource
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