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  • 1995-1999  (4)
  • 1985-1989  (8)
  • 1955-1959  (1)
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Year
  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of chemical & engineering data 40 (1995), S. 523-525 
    ISSN: 1520-5134
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1365-2826
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Corticotrophin-releasing hormone (CRH) is a 41 amino acid neuropeptide which plays a major role in regulating the endocrine response to stress. CRH acts by first binding to specific receptors on the plasma membrane of target cells. A CRH receptor from a human corticotroph adenoma and rat brain has recently been cloned (CRH-R1). In this paper, we have chosen three different peptide sequences within the CRH-R1 molecule which bear no similarity to other members of this receptor subfamily (or indeed any known protein) and which are likely to be exposed on the surface of the native protein, for antibody production. Some of these fragments produced anti-peptide antibodies of good titre which cross-reacted with the CRH-R1 receptor expressed in transiently transfected COS-7 cells and in tissue extracts from rat cerebellum, cortex, pituitary gland and human myometrium, both in Western blots and in liquid-phase radioimmunoassay. We used immunofluorescence techniques to localize the CRH receptor in transiently transfected COS-7 cells, primary cultures of rat anterior pituitary (AP) cells, the corticotroph-tumour cells AtT20 D16–16 and cortical neurons in primary culture. Our results indicate IR-CRH-R1 receptors have a punctate distribution on the plasma membrane of AP cells and AtT20 D16–16 cells. Whilst in AP cells their appearance is a fine punctate pattern, in AtT20 cells, they appear as large patches which could account for receptor clusters. Within primary cortical neurons, their distribution does not appear to be polarized. Our results suggest that distribution of CRH-R1 receptors within the different cell-types investigated depends not only on the amino acid sequence but also on cellular factors.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 177 (1956), S. 900-900 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] There was a highly significant difference in body temperature and respiration-rate on different days and throughout the day due to different weather conditions between and during days. From Table 1 it will be seen that the mean body temperature and respiration-rate of the buffaloes was lower than ...
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 42 (1986), S. 634-636 
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    The journal of Fourier analysis and applications 2 (1995), S. 303-314 
    ISSN: 1531-5851
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract In this article a generalized sampling theorem using an arbitrary sequence of sampling points is derived. The sampling theorem is a Kramer-type sampling theorem, but unlike Kramer's theorem the sampling points are not necessarily eigenvalues of some boundary value problems. The theorem is then used to characterize a class of entire functions that can be reconstructed from their sample values at the points tn = an + b if n = 0, 1, 2, ... and tn = an + c if n = 0, -1, -2, ..., where a, b, c are arbitrary constants. The reconstruction formula is derived explicitly in the form of a sampling series expansion. When a = 1, b = 0 = c, the famous Whittaker-Shannon-Kotel'nikov sampling theorem is obtained as a special case.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Meccanica 22 (1987), S. 123-132 
    ISSN: 1572-9648
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Description / Table of Contents: Summary A description and a review of the Hilbert transform procedures for detecting and quantifying structural non-linearity in frequency response functions obtained during modal testing is presented in this paper. A method of minimizing the effect of residual modes of vibration, previously a problem with the numerical Hilbert transform, is also described.
    Notes: Sommario Si descrivono e si riesaminano le procedure di trasformazione Hilbert per la scoperta e la quantificazione della non linearità strutturale nelle funzioni di risposta alla frequenza ottenute durante le prove modali. Si descrive anche un metodo per minimizzare l'effetto dei modi residui di vibrazione, già problematico per quanto riguarda la trasformazione numerica Hilbert.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Applied microbiology and biotechnology 28 (1988), S. 182-187 
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Acidogenesis and solventogenesis byClostridium beijerinckii NRRL B-593 has been studied in batch growth, and in sucrose-limited chemostat and recycling fermentor growth. Cells grown in batch culture without pH control primarily produced either butyric and acetic acids, or these acids plus butanol, ethanol and isopropanol in ratios depending on the medium's content of reducing agent, calcium and iron. Cells in chemostat-culture at a mass doubling time (td) of 5.8 h produced primarily butyric and acetic acids at pH 6.8 and these acids plus butanol, ethanol and isopropanol at pH 4.8. Cells grown in a recycling fermentor (in which the td continuously increases) at pH 6.8 entered solventogenesis at a td of 43 h, producing primarily propanol, ethanol and butanol, along with butyric acid, but with greatly decreased production of acetic acid. Although “clostridial form” morphology, succeeded by sporulation, usually accompanied solventogenesis, the association was not invariant so that solventogenesis and sporogenesis can occur separately in this species.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European radiology 9 (1999), S. 752-752 
    ISSN: 1432-1084
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1573-7438
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1573-7438
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé L'efficacité de l'oxytétracycline (OTC) seule ou combinée à la streptomycine pour traiter 118 brebis Najdi supposées avoir été naturellement infectées parBrucella melitensis, a été évaluée lors de l'abattage par la mise en culture de tissus et d'organes sélectionnés. Des groupes de moutons ont reçu 250, 500 ou 1000 mg d'OTC par voie intrapéritonéale (i/p) tous les jours pendant six semaines; à l'autopsie, on a trouvé respectivement 52, 69 et 100% des moutons libres de Brucella. Le traitement avec 250 mg d'OCT (quotidiennement pendant six semaines, i/p) combiné à 1000 mg de streptomycine (quotidiennement pendant trois semaines par voie intramusculaire) a augmenté le pourcentage de moutons sans Brucella à 82%. En inoculant un groupe de moutons recevant chacun 1000 mg d'OTC à longue action par voie i/p tous les trois jours pendant une période de six semaines, 75% d'entre eux ont été trouvés libres deBrucella à l'autopsie.B. melitensis a été isolé de tous (24) moutons non traités (contrôlés). Les résultats montrent qu'un traitement à long terme avec l'OTC seule à haute dose a permis d'éliminerB. melitensis d'un groupe de 16 moutons naturellement infectés.
    Abstract: Resumen Se evaluó la eficacia de la oxitetraciclina (OTC) sola o en combinación con estreptomicina, en el tratamiento de 118 ovejas Najdi, infectadas naturalmente conBrucella melitensis. Cultivos selectivos de diferentes órganos en le matadero, sirvieron como base de evaluacióh del tratamiento antibiótico. Los diferentes grupos de ovejas se inyectaron con 250, 500 o 1000 mg de OTC vía intraperitoneal (i/p) diariamente, durante seis semanas y en los grupos respectivos a la necropsia se encontraron libres de brucelosis 52, 69 y 100% respectivamente. El tratamiento con 250 mg de OTC (diario por seis semanas i/p), combinado con 1000 mg de estreptomicina (diario por tres semanas intramuscular), incrementó el porcentaje de animales libres de brucelosis a un 82%. Cuando un grupo de ovejas fueron inoculadas cada una i/p con 1000 mg de oxitetraciclina LA, cada tres días por un período de seis semanas, 75% de ellas se encontraron libres de brucelosis a la necropsia. Se aislóB. melitensis de todos los controles (24) no tratados. Los resultados demuestran, que el tratamiento prolongado con una dosis alta de OTC solamente, ha sido exitoso en eliminarB. melitensis de un grupo de 16 ovejas naturalmente infectadas.
    Notes: Summary The efficacy of oxytetracycline (OTC) alone or combined with streptomycin in the treatment of 118 Najdi ewes believed to have been naturally infected withBrucella melitensis, was evaluated by culture of selected tissues and organs at slaughter. Groups of sheep were given 250, 500 or 1,000 mg of OTC intraperitoneally (i/p) daily for six weeks and in the respective groups at necropsy 52, 69 and 100% of sheep were found to beBrucella-free. Treatment with 250 mg OTC (daily for six weeks i/p) combined with 1,000 mg streptomycin (daily for three weeks intramuscularly) increased the percentage ofBrucella-free sheep to 82%. When a group of sheep were each inoculated i/p with 1,000 mg of long-acting OTC every three days over a period of six weeks, 75% of them wereBrucella-free at necropsy.B. melitensis was isolated from all (24) non-treated (control) sheep. The results showed that long-term treatment with a high dose of OTC alone had succeeded in eliminatingB. melitensis from a group of 16 naturally infected sheep.
    Type of Medium: Electronic Resource
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