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  • 1
    ISSN: 1432-0827
    Keywords: PTHrP ; Articular cartilage ; Chondrocyte ; Development
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract Expression and localization of parathyroid hormone-related protein (PTHrP) in rat articular cartilage during fetal and postnatal periods were investigated by immunohistochemistry and in situ hybridization. PHTrP displayed distinct distribution and intensity of staining at different ages. In fetal (18-day-old) and young (3-week-old) rats, articular chondrocytes expressed abundant PTHrP throughout the entire thickness of cartilage. In contrast, in 60-week-old rats, PTHrP was expressed in a few articular chondrocytes of superficial and middle layers. Regulation of PTHrP and PTH/PTHrP receptor mRNA was also studied in cultured rat articular chondrocytes. Northern blot analysis revealed that both transforming growth factor-β (TGF-β), an important stimulator for chondrocyte proliferation and differentiation, and 10% fetal bovine serum (FBS) stimulated the expression of PTHrP mRNA with down-regulation of its receptor mRNA. In contrast, 12-O-tetradecanoylphorbol-13-acetate (TPA) down-regulated the expression of receptor without changes of PTHrP mRNA level. These results suggest that the changes in abundance and localization of PTHrP and its receptor may be directly involved in the cell growth and differentiation of articular cartilage.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 30 (1988), S. 571-573 
    ISSN: 1432-1920
    Keywords: Magnetic resonance imaging ; Ossification of ligamentum flavum ; Thoracic myelopathy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A case of thoracic myelopathy due to ossification of the ligamentum flavum is presented. A fifty-five year old female complained of sensory and motor disturbance of lower limbs. Neuroradiologically, in addition to ossification of the posterior longitudinal ligament throughout the spines, ossified ligamenta flava were found at the Th10–11 level and magnetic resonance imaging (MRI) clearly showed the spinal cord compressed at the same level by a low-intensity-signal lesion. Laminectomy and removal of the ossfied ligamenta flava improved her neurological dysfunction. The usefulness of the MRI in the neuroradiological diagnosis was confirmed.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Graphs and combinatorics 3 (1987), S. 25-38 
    ISSN: 1435-5914
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract One of the main results says that ifC is a binary linear code of length 4t and of dimension greater than 2t, thenC contains a word of weight 2t and this bound is best possible. Several results of similar flavor are established both for linear and non-linear codes. For the proof a lemma introducing the binormal forms of binary matrices is needed. The results are applied to determine the coset chromatic number of Hadamard graphs, to solve a problem of Galvin and to give a short proof of a theorem of Gleason on self-dual doubly-even codes.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of applied electrochemistry 28 (1998), S. 855-862 
    ISSN: 1572-8838
    Keywords: electroplating ; Fe–C alloys ; hard deposits ; bath composition ; covering power ; effects of chloride
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Notes: Abstract Fairly uniform Fe–C alloy deposits with bright appearance and characteristic black colour were obtained in Hull cell tests at 1.0A from baths with the following composition: FeSO4 0.5m or higher, citric acid 0.01m or lower, and pH around 2.0. The carbon content of the deposits from these baths ranged between 1.0 and 1.2wt% and the Vickers hardness was HV700 or above over a wide area of the Hull cell cathode. The thickness distribution of the deposits on the Hull cell cathode from these baths suggested that the current efficiency was 100% and the local current density obeyed the primary current distribution, except for the region near the low-current-density (LCD) end where the thickness decreased unexpectedly. The addition of chloride ion as NaCl, at concentrations of 1.0m or above, improved the thickness in the LCD region, and the thickness distribution on the Hull cell cathode suggested that current efficiency was 100% even at the LCD end. Chloride ion did no t affect the carbon content or the hardness of the deposits. Polarization measurements showed that the hydrogen ion reduction occurred at more noble potentials than Fe deposition. The unexpected thickness decrease near the LCD end, observed in Hull cell tests, and the improvement of this by adding chloride ion were both accounted for by the change in the preceding hydrogen ion reduction rate. The increase in citric acid concentration enhanced hydrogen ion reduction and therefore caused a lowering of current efficiency at low current densities. On the other hand, the addition of chloride ion inhibited hydrogen ion reduction and caused an increase in current efficiency at low current density.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Documenta ophthalmologica 71 (1989), S. 329-340 
    ISSN: 1573-2622
    Keywords: aging ; amplitude ; implicit time ; visual evoked potential ; Weiner kernel
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Visual evoked potentials were obtained from 112 subjects (215 eyes) aged 5 to 79 years with fast random stimuli. The stimulus (the presence or absence of the initiation of a reversal) and response (voltage measurements) were used in calculating the first order Wiener kernels to obtain the visual evoked potentials. Five check sizes were used to stimulate each eye. The implicit time of the major negative wave showed a significant increase with age for each check size used. Regression lines for the implicit time vs age data for male subjects were significantly different from those of females. The y-intercepts were lower and the slope of the regression lines were consistently steeper for males. Thus the rate of increase in implicit time was higher in males. The relationship of the amplitude of the major wave to age did not appear to be linear. The data suggested that a second-order polynomial curve might be an appropriate representation of the relationship.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1777
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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