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  • 1995-1999  (6)
  • 1990-1994  (2)
  • 1985-1989  (3)
  • 1940-1944  (1)
  • 1935-1939  (1)
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  • 1
    Digitale Medien
    Digitale Medien
    Combined Administration of a 5-Hydroxytryptamine (5-HT)1D Antagonist and a 5-HT Reuptake Inhibitor Synergistically Increases 5-HT Release in Guinea Pig Hypothalamus In Vivo (1996)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 67 (1996), S. 0 
    Details
    ISSN: 1471-4159
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Abstract: In vivo microdialysis in guinea pig hypothalamus was used to study the effect of serotonin [5-hydroxytryptamine (5-HT)] subtype 1D autoreceptor blockade on the increase in extracellular 5-HT levels produced by a selective 5-HT reuptake inhibitor (SSRI). Administration of the selective 5-HT1D antagonist GR127935 at 0.3 mg/kg had no effect, but 5 mg/kg significantly increased extracellular levels of 5-HT and 5-hydroxyindoleacetic acid to 135% of basal values. Moreover, at these doses GR127935 significantly attenuated the decrease in extracellular 5-HT levels following local perfusion with the selective 5-HT1D agonist CP-135,807. The SSRI sertraline at 2 mg/kg increased 5-HT levels to 130% of basal levels. The combination of this low dose of sertraline with either dose of GR127935 resulted in a pronounced, long-lasting increase in 5-HT levels to 230% of basal values. These results indicate that the effects of an SSRI on terminal 5-HT are significantly enhanced by coadministration of a 5-HT1D antagonist and confirm that in addition to somatodendritic 5-HT1A autoreceptors, terminal 5-HT1D autoreceptors mitigate the effect of SSRIs on terminal 5-HT. As such, antagonists of the 5-HT1D autoreceptor could be useful as rapidly acting antidepressants and may shorten the onset of antidepressant action when combined with SSRIs.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1046/j.1471-4159.1996.67052204.x
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  • 2
    Digitale Medien
    Digitale Medien
    In Defence Of Mutuality (1998)
    Oxford, UK and Boston, USA : Blackwell Publishers Ltd
    Business ethics 7 (1998), S. 0 
    Details
    ISSN: 1467-8608
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Philosophie , Wirtschaftswissenschaften
    Notizen: “There was something a little unseemly about how the building societies intending to demutualise did so by encouraging their members to vote in favour with the inducement of significant payments in shares”. Should one have no regard for the intentions of those who produced the present capital accumulation, or for the idea of holding reserves in trust for future members? The author is DBM Professor of Corporate Governance at Leeds Business School, Leeds Metropolitan University, Calverley Street, Leeds LS1 3HE.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/1467-8608.00094
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  • 3
    Digitale Medien
    Digitale Medien
    Introduction: Pacific Paradigms (1999)
    Oxford, UK and Boston, USA : Blackwell Publishers Ltd
    Creativity and innovation management 8 (1999), S. 0 
    Details
    ISSN: 1467-8691
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Wirtschaftswissenschaften
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/1467-8691.00113
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  • 4
    Digitale Medien
    Digitale Medien
    Review Essay: Mapping out the Field (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Corporate governance 2 (1994), S. 0 
    Details
    ISSN: 1467-8683
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Politikwissenschaft , Wirtschaftswissenschaften
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1467-8683.1994.tb00083.x
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  • 5
    Digitale Medien
    Digitale Medien
    Research on Corporate Governance (1998)
    Oxford, UK and Boston, USA : Blackwell Publishers Ltd
    Corporate governance 6 (1998), S. 0 
    Details
    ISSN: 1467-8683
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Politikwissenschaft , Wirtschaftswissenschaften
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/1467-8683.00081
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  • 6
    Digitale Medien
    Digitale Medien
    Case Study: Robert Maxwell: Master of Corporate Malfeasance (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Corporate governance 1 (1993), S. 0 
    Details
    ISSN: 1467-8683
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Politikwissenschaft , Wirtschaftswissenschaften
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1467-8683.1993.tb00028.x
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  • 7
    Digitale Medien
    Digitale Medien
    Problems faced by R&D managers in Canadian federal government laboratories (1988)
    Oxford, UK : Blackwell Publishing Ltd
    R & D management 18 (1988), S. 0 
    Details
    ISSN: 1467-9310
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Wirtschaftswissenschaften
    Notizen: The paper conducts a critical review of the problems faced by middle to first-line managers in managing R&D in Canadian government laboratories. The data come from the published literature, interviews with R&D managers, and information obtained from government employees undergoing training as R&D managers.The problems are numerous and serious. They arise from a multiplicity of causes related to underfunding and bureaucratic management practices that do not allow for the special nature of R&D. Hiring freezes, staff reductions, travel restrictions and reductions in training budgets are all consequences of underfunding, resulting in an aging workforce and technological obsolescence. Bureaucratic administration rules set by central agencies constrain the freedom of R&D managers to manage effectively, and limit low-level participation in policy-making and planning. The result is that too many management posts are filled by under-achieving scientists and engineers, with resultant consequences for originality and efficiency.The authors believe that the only cure is to undertake proper funding, recognise the special operational needs of R&D management, and select managers for managerial ability in addition to technical competence.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1467-9310.1988.tb00561.x
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  • 8
    Digitale Medien
    Digitale Medien
    The contribution of non-executive directors to the effectiveness of corporate governance (1998)
    Bingley : Emerald
    Career development international 3 (1998), S. 118-124 
    Details
    ISSN: 1362-0436
    Quelle: Emerald Fulltext Archive Database 1994-2005
    Thema: Wirtschaftswissenschaften
    Notizen: Examines the role of non-executive directors. Argues that there is universal agreement on the need for outsiders to be involved in company direction and that shareholders are not able to provide the necessary checks and balances to supervise board activities. Examines research on the system of non-executive directors. Argues that there is a need to develop procedures to select non-executives that are rigorous and add value. Concludes that non-executive directors will have increasing influence on company direction.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1108/13620439810211117
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  • 9
    facet.materialart.
    Unbekannt
    Spirituality, Justice, and Cultural Evangelization (1988)
    New Haven, Conn., etc. : Periodicals Archive Online (PAO)
    Religious Education. 83:1 (1988:Winter) 53 
    Details
    ISSN: 0034-4087
    Thema: Theologie und Religionswissenschaft
    Notizen: Theme: "Spirituality and Religious Education"
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:3226-1988-083-01-000017
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  • 10
    Digitale Medien
    Digitale Medien
    The stakeholder approach to the firm: a practical way forward or a rhetorical flourish? (1996)
    Bingley : Emerald
    Career development international 1 (1996), S. 39-41 
    Details
    ISSN: 1362-0436
    Quelle: Emerald Fulltext Archive Database 1994-2005
    Thema: Wirtschaftswissenschaften
    Notizen: Discusses the recent interest in a stakeholder approach as an alternative approach to competitive individualism in organizations. Examines the economic philosophy which underpins the traditional view of shareholder primacy and explores whether the approach is viable and realistic in contemporary circumstances. Concludes that in future, the stakeholder approach may be a commercial necessity.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1108/13620439610114333
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