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Digitale Medien

Zur Struktur neuartiger ThiatriazinsystemeStereochemische Untersuchungen heterocyclischer Verbindungen. XVII [1]. (1986)

Teller, M. ; Fischer, E. ; Martin, D. ; [weitere]

New York, NY : Wiley-Blackwell

Journal für Praktische Chemie/Chemiker-Zeitung 328 (1986), S. 199-204

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ISSN: 0021-8383

Schlagwort(e): Chemistry ; Organic Chemistry

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Chemie und Pharmazie

Notizen: Structure of New Systems of ThiatriazinesDepending on the nucleophilicity of exocyclic nitrogen in 2-guanidino-benzimidazole-1-carbimidic esters and 1-carbamides cyclization with N-sulfinyl amines leads to new 3-amino-1λ4, 2,4,6-thiatriazino[2,3-a]benzimidazole-1-oxide-5-carbimidic esters (3), 1-oxide-5-carbamides (5) and 3-(4-chlorphenylamino)-1-toluene-sulfonylimino-1λ4,2,4,6-thiatriazino[2,3-a]benzimidazole-5-carbimidic ester (7).

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/prac.19863280208

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Digitale Medien

Catalase activity in human spermatozoa and seminal plasma (1989)

Jeulin, C. ; Soufir, J. C. ; Weber, P. ; [weitere]

New York, NY : Wiley-Blackwell

Gamete Research 24 (1989), S. 185-196

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ISSN: 0148-7280

Schlagwort(e): free radicals ; Life and Medical Sciences ; Cell & Developmental Biology

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Biologie

Notizen: Catalase activity was determined in human semen by measuring the oxygen burst with a Clark electrode, after H2O2 addition. Significant catalase activities (mean ± SD) were found in migrated, motile spermatozoa (44 ± 17 nmoles O2/min/108 cells) and in seminal plasma of normozoospermic men (129 ± 59 nmoles O2/min/ml). It has been demonstrated that seminal catalase originated from prostate; however, its activity was not correlated with the usual prostatic markers (such as citric acid and zinc). Our data suggest a multiglandular function secreted by this organ. The catalase activities measured in seminal samples from asthenozo-ospermic, infertile men were found lower than those from normozoospermic subjects. The understanding of the relative contribution of the different enzyme systems against O2 toxicity (superoxide dismutase, catalase, glutathione peroxidase) seem to be a priority area of research to understand disturbances of sperm function.

Zusätzliches Material: 3 Ill.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/mrd.1120240206

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