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Digitale Medien

Ultrastructural aspects of nerves, bones, and vessels in hereditary sensory neuropathy (1985)

Teot, L. ; Arnal, F. ; Humeau, C. ; [weitere]

Hoboken, NJ [u.a.] : Wiley-Blackwell

Journal of Orthopaedic Research 3 (1985), S. 226-235

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Details

ISSN: 0736-0266

Schlagwort(e): Hereditary sensory neuropathy ; Bone resorption ; Osteoclasts ; Vascular reflex ; Life and Medical Sciences

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Medizin

Notizen: This study concerns two children, from the same otherwise normal family, presenting progressive spontaneous amputations of the limbs, suggesting peripheral hereditary sensory neuropathy. Samples from the distal nerves and vessels and the distal tibial epiphyses were examined ultrastructurally. The nerves showed signs of degeneration, and a typical bone necrosis, without osteoclasts, was observed in the 2 cm margin of the samples. Simultaneous modifications of the vessels suggest a neurally initiated vascular reflex resulting in bone destruction. Theories that might explain the observations are discussed.

Zusätzliches Material: 10 Ill.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/jor.1100030213

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