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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 108 (1986), S. 5531-5536 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0942-0940
    Keywords: Head injury ; intracranial pressure ; metabolism ; nitrogen balance ; oxygen consumption
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Both metabolic rate and protein catabolism are known to increase following severe head trauma, but the etiology of this hypermetabolism is unknown. To further investigate the problem, we studied the metabolism of 17 patients with indirect calorimetry who had severe craniocerebral trauma only and who required ICP monitoring for management. Patients were studied daily and immediately after ICP spikes greater than 20 mmHg, prior to treatment with hyperventilation, osmotic diuretics, or barbiturates. Oxygen consumption (VO2) was correlated with ICP. Two groups of patients were identified. Group I patients were treated with hyperventilation and osmotic diuretics while Group II patients additionally received cerebral metabolic depressants. Group I had a significant correlation coefficent between VO2 and ICP. Significant hypercatabolism early in the post trauma period was demonstrated by increased urine urea nitrogen. Our observations suggest that in patients with craniocerebral trauma, elevated ICP is associated with increased oxygen consumption, protein catabolism and systemic hypermetabolism. Cerebral metabolic depressants blunted increases in VO2 which were seen with elevated ICP.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 88 (1988), S. 6585-6593 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: A new method which should have relatively general applicability for the identification and quantitative analysis of reactive adsorbed molecular intermediates in surface reactions will be described, and the first examples of its application will be presented. When a reactive intermediate is generated on a surface, it often has a tendency to dissociate before desorbing. Since dissociation generally requires additional free sites on the surface, dissociation can be suppressed and desorption correspondingly enhanced if the free sites on the surface can be properly poisoned. We have found that bismuth adatoms are very good inert site blockers, which can be postdosed to the surface of a transition metal containing a reactive adsorbed hydrocarbon without destroying the hydrocarbon. Whereas in the absence of bismuth, the hydrocarbon would completely dehydrogenate during thermal desorption spectroscopy (TDS) and liberate only H2 into the gas phase, after bismuth postdosing the reactive hydrocarbon desorbs intact for mass spectral identification and quantitative analysis. This method has been used to prove that adsorbed benzene is the initial product of the dehydrogenation of cyclohexane on Pt(111) at ∼235 K. In the absence of bismuth, this benzene all dissociates during TDS to liberate only H2, leaving graphitic carbon residue on the surface. When one-third monolayer of Bi is postdosed at 110 K, the dehydrogenation pathway is sterically poisoned and the adsorbed benzene quantitatively desorbs during TDS, where it is unambiguously identified by mass spectroscopy. By briefly heating the reactive adsorbed intermediate to increasing temperatures prior to Bi deposition, the thermal stability limits of the intermediate and the kinetic parameters for its dissociation can be established. This is demonstrated for the dehydrogenation reaction of adsorbed cyclopentene on Pt(111). Bismuth postdosing in thermal desorption mass spectroscopy (BPTDS) should be a very useful but inexpensive addition to surface analytical capabilities.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 59 (1988), S. 2031-2035 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: We have investigated the use of frequency variation in ac calorimetry in the measurement of thermal quantities within controllable distances of the sample heater and thermometer. This technique, useful in studies of heterogeneous samples where only a small part of the sample is of interest, e.g., surfaces, thin films, and interfaces, is applied to study the thermal properties of a test sample made from indium (In) sandwiched between layers of bulk gallium arsenide. We measure and analyze the frequency dependence of the thermal response of the sample, as well as the variation with frequency of the relative size of the anomaly observed at the In superconducting transition. The data are consistent with a model assuming a thermal diffusion-limited sampling volume.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Biochemistry 55 (1986), S. 733-771 
    ISSN: 0066-4154
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Chemistry and Pharmacology , Biology
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 15 (1988), S. 0 
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. Two groups of spontaneously hypertensive rats (SHR) were treated with enalapril (25–30 mg/kg per day): Group I received treatment from 4 to 14 weeks of age to inhibit development of hypertension and Group R received the drug from 14 to 20 weeks of age to reverse established hypertension.2. Systolic blood pressure, ploidy of aortic smooth muscle cells (flow cytometric DNA analysis) and aortic hypertrophy (medial cross-sectional area) were determined at times both during and after enalapril treatment (up to 30 weeks).3. Enalapril treatment normalized blood pressure to that of age-matched Wistar-Kyoto rats in both groups. Blood pressure rose again following cessation of treatment.4. In untreated SHR the incidence of polyploid cells increased concomitantly with increasing pressure throughout the time studied, whereas in Group I the incidence remained low. In Group R, the incidence of polyploidy directly paralleled both the decrease (normalization) and the rise in blood pressure following cessation of treatment.5. Hence, the incidence of vascular smooth muscle cell polyploidy is not simply a result of growth of the vessel with increasing age of the SHR, but parallels inhibition, reversal, and redevelopment of hypertension.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 14 (1987), S. 0 
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A sample consisting of 1135 edentulous patients with clinically healthy denture bearing areas, was examined radiologically. It appears that the diagnostic yield is high whereas the expected radiation induced risk is low. Patients should therefore be examined radiologically prior to full denture construction.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Weed research 27 (1987), S. 0 
    ISSN: 1365-3180
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Quackgrass [Elymus repens (L.) Gould =Agropyron repens (L.) Beauv.] and barnyardgrass [Echinochloa crus-galli (L.) Beauv.] were more than one hundred times more susceptible to sethoxydim than alfalfa (Medicago sativa L. 'Saranac') or navybean (Phaseolus vulgaris L. 'Seafarer'). Uptake of sethoxydim From soil following post-emergence applications caused negligible reduction in E. crus-galli fresh weight. More than 80% of foliar-applied 14C-sethoxydim was absorbed within 6 h in all species. Translocation occurred in all species with accumulation of 14C in rapidly growing plant tissues. Translocation to the roots was less than 8% of total in all species. Most of the extracted 14C initially partitioned into an ethyl acetate-soluble fraction. The proportion of 14C in the ethyl acetate-soluble fraction decreased with time with a concomitant increase of that in the insoluble fraction. Differences in the quantity of 14C in the ethyl acetate-soluble fraction did not account for the observed selectivity.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 93 (1989), S. 815-826 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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