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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Journal of clinical monitoring and computing 4 (1988), S. 103-106 
    ISSN: 1573-2614
    Schlagwort(e): Monitoring: carbon dioxide ; oxygen ; Anesthesia, pediatric ; Oxygen: tension, arterial ; Carbon dioxide: tension, arterial
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Informatik , Medizin
    Notizen: Abstract We evaluated a new combined sensor for monitoring transcutaneous carbon dioxide tension (PtcCO2) and oxygen tension (PtcO2) in 20 critically ill newborn infants. Arterial oxygen tension (PaO2) ranged from 16 to 126 torr and arterial carbon dioxide tension (PaCO2) from 14 to 72 torr. Linear correlation analysis (100 paired values) of PtcO2 versus PaO2 showed anr value of 0.75 with a regression equation of PtcO2=8.59+0.905 (PaO2), while PtcCO2 versus PaCO2 revealed a correlation coefficient ofr=0.89 with an equation of PtcCO2=2.53+1.06 (PaCO2). The bias between PaO2 and PtcO2 was −2.8 with a precision of ±16.0 torr (range, −87 to +48 torr). The bias between PaCO2 and PtcCO2 was −5.1 with a precision of ±7.3 torr (range, −34 to +8 torr). The transcutaneous sensor detected 83% of hypoxia (PaO2 〈45 torr), 75% of hyperoxia (PaO2 〉90 torr), 45% of hypocapnia (PaCO2 〈35 torr), and 96% of hypercapnia (PaCO2 〉45 torr). We conclude that the reliability of the combined transcutaneousPo 2 andPCo 2 monitor in sick neonates is good for detecting hypercapnia, fair for hypoxia and hyperoxia, but poor for hypocapnia. It is an improvement in that it spares available skin surface and requires less handling, but it appears to be slightly less accurate than the single electrodes.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Child's nervous system 3 (1987), S. 103-105 
    ISSN: 1433-0350
    Schlagwort(e): Head injury ; Children ; Dexamethasone ; Endogenous cortisol
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Glucocorticoids are used in an attempt to reduce brain edema secondary to head injury. Nevertheless, their usefulness remains uncertain and contradictory. In a randomized study of 24 children with severe head injury, urinary free cortisol was measured by radioimmunoassay. Twelve patients (group 1) received dexamethasone and 12 (group 2) did not. All patients were treated with a standardized regimen. In group 1 there was complete suppression of endogenous cortisol production. In group 2 free cortisol was up to 20-fold higher than under basal conditions and reached maximum values on days 1–3. Since the excretion of cortisol in urine reflects the production rate closely and is not influenced by liver function and barbiturates, the results in group 2 show that the endogenous production of steroids is an adequate reaction to severe head injury. Exogenous glucocorticoids are thus unlikely to have any more beneficial effects than endogenous cortisol.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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