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  • 1
    Electronic Resource
    Electronic Resource
    Nuclear medicine liver function tests for pregnant women and children 1. Breath tests with 14C-methacetin and 13C-methacetin (1985)
    Springer
    European journal of nuclear medicine 10 (1985), S. 129-133 
    Details
    ISSN: 1619-7089
    Keywords: carbon-13, carbon-14 ; children ; diagnostic techniques ; diseases ; double labelling ; drugs ; isotope applications ; liver ; function tests ; metabolism ; pregnant women ; synthesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Stable isotopes, such as 13C, should be substituted for the long-lived radionuclide 14C in the 14C breath test when doing liver function tests in children and pregnant women. For comparison 13C, 15N-methacetin and 14C-methacetin were synthesized as suitable diagnostic agents. Methods are described for the measurement of 14C and 13C in the breath. After oral administration of labelled methacetin to healthy subjects and patients with liver diseases a good correspondence between 13C- and 14C-measurements in the same subject on the one hand, and a good discrimination between controls and patients on the other hand were shown. Findings with regard to 14C measurements in urine are discussed supporting the supposed advantage of 13C-methacetin over 14C-methacetin application.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00252720
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  • 2
    Electronic Resource
    Electronic Resource
    A liver-function test using 15N-labelled ammonium chloride (1985)
    Springer
    European journal of nuclear medicine 11 (1985), S. 62-64 
    Details
    ISSN: 1619-7089
    Keywords: Ammonia ; Diagnosis ; Emission spectroscopy ; Isotope application ; Liver ; Nitrogen-15 ; Tracer technique ; Urea
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Malfunction of the liver involves disturbances of urea synthesis and ammonia detoxification. These phenomena became apparent, especially during ammonia loading of patients. The functional state of the liver can be assessed by oral administration of 15NH4Cl and subsequent analysis of 15N-urea and 15N-ammonia in urine by emission spectrometry. Clinical tests based on the ratio of the excess abundances (see Appendix) of 15N-ammonia to 15N-urea excreted in urine 3 h after oral administration gave values for patients with liver disease which differed significantly from those for healthy subjects. Absorption disturbances, which often accompany liver diseases, do not influence the effectiveness of the method.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00252134
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Nuclear medicine liver-function tests for pregnant women and children (1985)
    Springer
    European journal of nuclear medicine 11 (1985), S. 58-61 
    Details
    ISSN: 1619-7089
    Keywords: Children ; Diagnostic techniques ; Diseases ; Drugs ; Function tests ; Isotope applications ; Liver ; Metabolism ; Nitrogen-15 ; Pregnant women ; Stable isotopes ; Urine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A simple, non-invasive, non-radioactive liverfunction test is proposed. After an oral dose of 3 mg 15N-methacetin per kilogram body mass, the kinetics of 15N excretion via urine were characterized by the quotient of the amounts of 15N excreted in two successive urine samples (Q value). The stable nitrogen isotope 15N was found to be an excellent and easily detectable indicator of the sum of all methacetin metabolites present in urine. Alterations in the nature or ratio of methacetin metabolites due to liver diseases could not be found. From the investigation of 11 men, 3 pregnant women and 15 children, a clear difference was observed in Q values of healthy persons and patients suffering from liver-cell-activity diseases. The discriminating power of our new liver-function test is shown to be equivalent to that of the 14CO2 breath test.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00252133
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  • 4
    Electronic Resource
    Electronic Resource
    Nuclear structure effects in the mass region aroundA=100, derived from experimentalQ β -values (1987)
    Springer
    The European physical journal 327 (1987), S. 383-392 
    Details
    ISSN: 1434-601X
    Keywords: 21.l0.Dr ; 27.60.+j
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The endpoint energies ofβ-transitions in 15 neuron-rich nuclei with mass numbers 101≦A≦106 have been measured with a plastic scintillator telescope in coincidence with a large Ge(Li)-detector at the on-line mass separator LOHENGRIN. From theQ β -values obtained in these experiments, nuclear structure effects in this region of the nuclear chart are deduced. Finally, nuclear masses derived from theseQ β -values are compared with the predictions of different theoretical mass calculations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01289562
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Experimental Beta-decay energies of very neutron-rich fission products with 107≦A≦109 (1989)
    Springer
    The European physical journal 334 (1989), S. 239-245 
    Details
    ISSN: 1434-601X
    Keywords: 21.10.Dr ; 27.60.+j
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Theβ-decay of neutron-rich fission products with mass numbersA=107, 108 and 109 has been investigated at the mass separator LOHENGRIN of the Institute Laue-Lange-vin (ILL) in Grenoble by measuringβγ-coincidences with a large plastic scintillator telescope and a Ge(I)-detector. Theβ-decay energies of 8 nuclei were obtained from the evaluation of more than 40β-endpoint energies. For the nuclei107 Mo,107Tc,108Tc,109Tc and109Ru, theβ-decay energies were determined for the first time; the experimental error in the decay energy of three daughter nuclei was considerably reduced. In addition, the two-neutron separation energies and the nuclear mass excesses were calculated from these experimentalQ β-values and compared with different mass predictions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01284550
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    Paper (German National Licenses)
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