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  • 1
    Electronic Resource
    Electronic Resource
    Calcium homeostasis in premature infants and treatment of early hypocalcaemia by 1,25-dihydroxycholecalciferol (1987)
    Springer
    European journal of pediatrics 146 (1987), S. 383-386 
    Details
    ISSN: 1432-1076
    Keywords: Early neonatal hypocalcaemia ; 1,25-dehydroxycholecalciferol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We studied calcium homeostasis and the serum calcium response to oral 1,25-dihydroxycholecalciferol [1,25 (OH)2D3] at a low pharmacological dosage of 0.1 μg/kg daily in 14 early hypocalcaemic asymptomatic neonates. Seven hypocalcaemic neonates were not treated. In hypocalcaemic neonates serum PTH levels were normal, the urinary C-AMP response after PTH stimulation was poor and plasma 1,25 (OH)2D3 was low. Treatment with 1,25(OH)2D3 resulted in a rapid increase of serum calcium. The increase was more rapid in neonates treated with 1,25(OH)2D3 than in untreated subjects. A similar result was obtained in one of a pair of identical twins. These results suggest that a low dose of 1,25(OH)2D3 is effective in treating neonatal hypocalcaemia. However, the response was delayed for 48 h. The reason for this delay is not clear.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00444943
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Deposition of a Si monolayer on sapphire using an ArF excimer laser for Si epitaxial growth (1988)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 64 (1988), S. 2087-2091 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Si monolayer deposition on sapphire substrates was investigated by in situ x-ray photoelectron spectroscopy (XPS). Si deposition was carried out using direct photolysis of Si2H6 by irradiation of 193 nm ArF excimer laser light (1–2 W/cm2 , 70 Hz) at room temperature in a high-vacuum chamber. At first, decomposed Si atoms bound strongly with O atoms on sapphire until the entire sapphire surface was covered, then SiSi bonds were formed. From the growth mode analysis of the early stage of Si deposition, it can be seen that the growth mode of the deposited layer is a layer-by-layer mode (the Frank–Van der Merwe-type growth). The thickness of the deposited Si layers can be controlled on an atomic scale. As these features are suitable for Si-on-sapphire (SOS) epitaxial growth with predeposited layers, SOS epitaxial growth was demonstrated and the SOS films were characterized by replica electron microscopy and fabricating a metal-oxide-semiconductor field-effect transistor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.341717
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Characterization of reference strains of Newcastle disease virus (NDV) and NDV-like isolates by monoclonal antibodies to HN subunits (1985)
    Springer
    Archives of virology 85 (1985), S. 109-121 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The hemagglutinin-neuraminidase (HN) subunits of NDV and NDV-like isolates were analyzed antigenically by monoclonal antibodies to the HN of Miyadera and Taka viruses. In immuno-double-diffusion (IDD) tests, all NDVs examined gave clear lines of precipitation with some of the potent monoclonal antibodies, but it was difficult to determine with certainty the immunological properties of HN subunits due to a rare disagreement with the results obtained in other immunological tests. Monoclonal antibodies used in the tests were found to show different immunological reactivities with the viruses. Monoclonal antibodies belonging to the 1st group (1/29) inhibited the hemagglutinating (HA) activity of all strains but not the neuraminidase (NA) activity. The second monoclonal antibody (5/205) inhibited both the HA and NA activities of the restrictive NDV strains, indicating antigenic changes in HN molecules. However, the inhibitory activity of this monoclone to neuraminidase appeared to be greatly diminished when neuraminyl lactose was used as substrate. Although the 3rd type of monoclonal antibody (5/220) showed HI activity against several strains, this antibody did not inhibit NA activity of any viruses. The remaining monoclone to the HN of Taka virus inhibited the HA activity of all reference strains of NDV and many NDV-like isolates but did not affect NA activity. Two inhibitory activities of four monoclonal antibodies against different viruses, HI and hemolysis-inhibition, were not always consistent with inhibition of virus growth. HI and NI tests with the above four monoclonal antibodies showed that the strains tested fell into five antigenic groups according to their reaction patterns with mouse hybridoma antibodies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01317010
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  • 4
    Electronic Resource
    Electronic Resource
    Effects of amino acids on pancreatic polypeptide before and after vagotomy in the dog (1986)
    Springer
    Diabetologia 29 (1986), S. 262-264 
    Details
    ISSN: 1432-0428
    Keywords: Pancreatic polypeptide ; vagotomy ; amino acids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have previously indicated a marked influence of the vagus nerve on postprandial pancreatic polypeptide secretion. The present study was designed to determine whether the vagus nerve also plays a role in the regulation of pancreatic polypeptide secretion by absorbed nutrients. The pancreatic polypeptide responses to 17 intravenously administered amino acids, as well as arginine and glucose, were measured and compared with those 1 year after truncal vagotomy in conscious dogs. In response to the infusion of a mixture of amino acids (20 g during 60 min), plasma pancreatic polypeptide concentrations decreased in normal dogs. The effect was, however, completely reversed by vagotomy, with a significant pancreatic polypeptide release being observed (p 〈 0.05). Arginine (5 g during 60 min) also showed a similar, although not statistically significant, effect. After intravenous bolus-injection of glucose (0.5 g/kg body weight), a transient decrease of pancreatic polypeptide secretion was found; vagotomy abolished this response. These results suggest that the vagus nerve may have a suppressive role in the process of pancreatic polypeptide secretion induced by intravenous amino acid(s) and glucose.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00454888
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  • 5
    Electronic Resource
    Electronic Resource
    Antigenic characterization of hemagglutinin-neuraminidase (HN) protein of avian paramyxoviruses by specific antisera to isolated HN subunits (1985)
    Springer
    Archives of virology 83 (1985), S. 229-239 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Specific antisera for the isolated HN proteins of eight reference strains of avian paramyxoviruses could be prepared in guinea pigs by intraperitoneal injection of guinea pig red blood cells (GRBC) coated with purified HN proteins. In the hemagglutination inhibition (HI) tests, all reference strains reacted strongly with each homologous antiserum to the isolated HN showing that a low level of cross-reactivity among the reference strains was greatly diminished by using specific antisera. Immuno-double-diffusion (IDD) tests showed that all antisera except those to turkey/Wisconsin/68 and duck/Hong Kong/D3/75 gave single well-defined lines only with the homologous viruses. The remaining two antisera developed a single definite precipitin line together with weak lines with homologous virus. Two isolates in Japan were clearly identified in HI and IDD tests with specific antisera to the HN subunits of the reference strains suggesting that the antisera were useful for identification of avian paramyxovirus isolates. Two isolates in Japan, H-70 from a munia-bird and Y-7 from a duck were found to have HN proteins related closely to those of finch/N. Ireland/Bangor/73 and duck/Hong Kong/199/77, respectively.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01309919
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