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  • 1985-1989  (3)
  • 1
    ISSN: 1432-0533
    Keywords: Cerebral ischemia ; Hippocampus ; CA1 pyramidal cells ; Neuropathology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Transient forebrain ischemia produces a spatially and temporally selective pattern of neuronal degeneration in the hippocampal formation of the Mongolian gerbil. Ischemic neuronal death has been suggested to depend on the activation of excitatory hippocampal pathways that project to the vulnerable neurons. This idea was tested by examining the effect of a unilateral entorhinal cortical lesion or a unilateral knife cut lesion of intrahippocampal pathways on the neuropathology produced by 5 min of complete fore-brain ischemia. A prior lesion of either the ipsilateral entorhinal cortex or the mossy fiber and Schaffer collateral-commissural pathways partially prevented the destruction of CA1b pyramidal cells in most animals. It did not, however, reduce the extent of ischemic neuronal death in any other hippocampal subfield. Within area CA1b, an entorhinal lesion protected an average of 23% of the pyramidal cells and a transection of both mossy and Schaffer collateral-commissural fibers protected an average of 36.5%. CA1b pyramidal cells saved from ischemia-induced degeneration appeared clearly abnormal when stained with cresyl violet or by silver impregnation. It is suggested that lesions of excitatory pathways attenuate ischemic damage to area CA1b by directly or indirectly reducing the level of synaptic excitation onto the vulnerable neurons. However, only a relatively small percentage of hippocampal neurons can be protected by these lesions in the gerbil ischemia model and there is reason to believe that the neurons protected in this manner may not be electrophysiologically competent. Synaptic excitation therefore appears to play an important, but not an essential, role in this model of ischemic brain damage.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 63 (1988), S. 4226-4228 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The one-dimensional Hubbard model with first- and second-neighbor hopping, t1 and t2, with t2≈t1/(2)1/2 and large repulsion U, is proposed as a testing ground of Anderson's idea that the existence of an resonating valence bond ground state in the half-filled-band case will show superconductivity when a finite concentration of holes is introduced. Interestingly, our preliminary calculations in the U=∞ limit for small chains have revealed a new mechanism for enhancement of singlet pairing: We find that for t2〈0 the ground state is a singlet, and, for t2〈0 and ||t2/t1||(very-much-less-than)1, the nearest-neighbor extended-singlet-pairing correlation function becomes enhanced appreciably as the temperature decreases below t2.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 57 (1985), S. 3360-3360 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have calculated the 2-point correlation functions ωil(N)=(4/3)〈Si ⋅ Si+l〉 and their averages over i, ωl(N), in the ground state of the 1-dimensional antiferromagnetic Heisenberg model for N=4(2)16 spins. Both periodic (rings) and free-ends (chains) boundary conditions are considered. Surprisingly tight lower and upper bounds have been obtained for ωl(∞) under reasonable assumptions. In addition to showing the rather strong even-l-odd-l alternation in ||ωl(N)||, already known, our bounds indicate a smooth behavior in l||ωl(∞)|| for l odd and for l even, with, surprisingly, a broad maximum attained within the odd-l values at l(approximately-equal-to)6 to 8. The bounds obtained from the chain results were essential to seeing this maximum (because the l-values available for given N are larger than for rings). The quantity l||ωl(N)|| for chains with fixed N also shows such a maximum, and in addition shows a similar maximum for even l's. If the trends for large l and N which we have found continue in ωl(∞) and in SN, the structure factor at wave vector π, then finite-size contributions to ωl(N) will have to contribute to the (seemingly) logarithmic divergence of SN as N→∞. We are not aware of any models where a similarly weak divergence shows such a finite-size contribution. Earlier results, including ||ωl(∞)||≈A/l for l→∞, gave no hint of the decrease in l||ωl(∞)|| described above. Recently "logarithmic corrections'' have been mentioned, wherein ||ωl(∞)||≈(A/l) (ln l+B)−1. This might be related to the decrease in l||ωl(∞)|| which we found. If finite-size corrections are neglected, then this 1/l ln l behavior would predict SN≈ln ln N for N→∞, as opposed to the trend SN∼ln N that we found; continuation of the latter trend would then have to be due entirely to the finite-size contributions. Some insight into various surprising aspects of ωil(N) is gained by considering a single-band model of noninteracting electrons, which is a special case of the Hubbard model, as is the Heisenberg model.
    Type of Medium: Electronic Resource
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