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  • 1
    Electronic Resource
    Electronic Resource
    Expression of the mutant gene for L-gulono-γ-lactone oxidase in scurvy-prone rats (1989)
    Springer
    Cellular and molecular life sciences 45 (1989), S. 126-129 
    Details
    ISSN: 1420-9071
    Keywords: L-gulono-γ-lactone oxidase ; ascorbic acid deficiency ; enzyme defect ; rat ; nuclei acid hybridization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A mutant strain of Wistar rats with L-gulono-γ-lactone oxidase deficiency has recently been established. To investigate this deficiency by DNA and RNA blot hybridization analyses, a fragment of a previously cloned cDNA encoding rat L-gulono-γ-lactone oxidase was used as a probe. When genomic DNA of the mutant rat was digested with several restriction enzymes, the probe hybridized to fragments of the same sizes as those produced from DNA of normal rats. Poly(A)+RNA from the liver of the mutant rat was found to contain an L-gulono-γ-lactone oxidase-specific mRNA of a normal size at a comparable level to that of normal rats. An in vitro translation experiment revealed that the mRNA programmed the synthesis of an enzyme protein which had the same molecular weight as that of the translational product of the normal mRNA, although the amount synthesized was markedly reduced as compared with that synthesized with the normal mRNA. In accordance with this observation, a very low but definite degree of L-gulono-γ-lactone oxidase activity was detected in the microsomes of the mutant rat by a newly developed, highly sensitive method.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01954844
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  • 2
    Electronic Resource
    Electronic Resource
    Visible and VUV spectroscopic diagnostics on Heliotron E (1988)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 59 (1988), S. 1533-1535 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Diagnostic applications of visible and VUV spectroscopic techniques, as applied to the currentless Heliotron E plasma device, are described. Visible spectroscopy has been used to measure (i) ion temperature, (ii) proton-to-electron density ratio, (iii) Zeff by charge exchange recombination from an intense neutral beam, (iv) radial electric field by poloidal rotation velocity measurement, and (v) electron density around an ablating pellet by a Stark profile. VUV spectroscopy has been used to investigate emission spectra due to multiply ionized impurity species. This information is used to measure the densities of these species, and to learn about the transport of these particles. Recently, a flat-field survey spectrometer has been constructed and used to study the emission spectra due to metallic impurities in ICRF-heated plasmas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1140187
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  • 3
    Electronic Resource
    Electronic Resource
    Double-pass high-resolution vibrational electron energy loss spectrometer (1987)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 58 (1987), S. 307-308 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A double-pass high-resolution vibrational electron energy loss spectrometer of 127° cylindrical electrostatic deflection type has been constructed for surface studies. In the direct mode, an electron current at the detector of 1.3×10−14 A is obtained with the energy spread (full width at half-maximum) of 2.4 meV for electrons whose energy at the sample position is 5 eV.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1139654
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  • 4
    Electronic Resource
    Electronic Resource
    NATRIURETIC EFFECT OF CHRONICALLY ADMINISTERED α-HUMAN ATRIAL NATRIURETIC POLYPEPTIDE IN SODIUM DEPLETED OR REPLETED CONSCIOUS SPONTANEOUSLY HYPERTENSIVE RATS (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 13 (1986), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. Hypotensive and natriuretic effects of chronically administered α-human atrial natriuretic polypeptide (α-hANP) were investigated in conscious spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY) in both sodium depletion and repletion.2. Systolic blood pressure was significantly reduced in SHR and WKY in both sodium deplete and replete states.3. Urinary sodium excretion was significantly increased in SHR and tended to be increased in WKY on sodium repletion, but remained unchanged on sodium depletion.4. It is suggested that extracellular fluid volume may be an important determinant factor of the natriuretic action of ANP but may not affect the hypotensive effect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1986.tb00920.x
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  • 5
    Electronic Resource
    Electronic Resource
    NATRIURETIC AND HYPOTENSIVE EFFECTS OF α-HUMAN ATRIAL NATRIURETIC POLYPEPTIDE IN ANAESTHETIZED DOCA-SALT HYPERTENSIVE RATS (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 13 (1986), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. Both natriuretic and hyportensive effects of α-human atrial natriuretic polypeptide (α-hANP) were investigated in anaesthetized DOCA-salt hypertensive rats and control rats.2. An intravenous injection of two doses (0.3 and 3.0 μg/kg body weight) of α-hANP produced a rapid and marked increase in natriuresis and fall in blood pressure in DOCA-salt rats.3. Natriuretic and hypotensive effects of α-hANP in DOCA-salt rats were significantly greater than those in the control rats.4. It is suggested that DOCA-salt rats may have an enhanced natriuretic and hypotensive responsiveness to α-hANP.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1986.tb00322.x
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  • 6
    Electronic Resource
    Electronic Resource
    Free-surface velocity measurement of shock-compressed alumina powder compact using a Fabry–Perot interferometer (1989)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 66 (1989), S. 1662-1666 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A Fabry–Perot interferometer system was used to measure the free-surface velocity of α-alumina powder compact. In situ pressure profile measurements using a pair of manganin gauges were also carried out to clarify the compaction process during compression and stress release. The Fabry–Perot system indicates that the reflectivity of the free surface of the powder material does not significantly change during the stress release process. An observed feature of the powder's stress release curve as determined by the manganin gauge suggests the existence of the residual voids in the shock compressed powder matrix even in the high shock pressure regime.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.344382
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  • 7
    Electronic Resource
    Electronic Resource
    Self-adjustable pre-event pulse generator for shock wave experiments (1987)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 58 (1987), S. 1755-1757 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A self-adjustable, pre-event pulse generator has been constructed for triggering diagnostic and driving instruments before impact in various shock experiments. The preset period before impact is based on the instant of impact and is independent of projectile velocity. A change in the target position is accounted for by a variable clock oscillator.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1139381
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  • 8
    Electronic Resource
    Electronic Resource
    Hydrodynamic instability in an ablatively imploded target irradiated by high power green lasers (1988)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Fluids 31 (1988), S. 2875-2883 
    Details
    ISSN: 1089-7666
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Time evolution of the ablation front displacement between concave and convex regions of a surface corrugated spherical target was observed by flash x-ray radiography. The results are compared with calculations based on the linearized fluid equation combined with a one-dimensional simulation to describe the ambient fluid motion. In the analysis, perturbation of the fluid is scaled up to kδ∼2π (k is the perturbation wavenumber and δ is the perturbation amplitude) for the acceleration phase with perturbation mode numbers of l=20 and 30. The practical perturbation of the target requires a relaxation time to form the nominal eigenstate of the Rayleigh–Taylor instability, which results in time delay of instability growth onset.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.866996
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  • 9
    Electronic Resource
    Electronic Resource
    Statistical method for efficient determination of electron temperature from pulse height analysis of soft x rays in Heliotron E (1989)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 60 (1989), S. 2838-2846 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A pulse-height-analysis (PHA) technique of soft x rays is applied to Heliotron E experiments. The primary interest of this measurement is the determination of the electron temperature. Since the number of photons measured in a PHA system is extremely restricted owing to a finite processing rate of the system, it is most important to use the full amount of information involved in the spectral data. The statistical estimator from the maximum-likelihood method is efficiently used for this purpose. The estimated temperature is in good coincidence with the temperature by the electron-cyclotron-emission measurement, which is calibrated by the laser Thomson scattering. A check of reliability of the estimated electron temperature is developed from a statistical test of goodness of fit. The identification of impurity lines buried in a thermal spectrum is also discussed in the spectra accumulated through several or several tens of plasma discharges. The line emissions from Si, Cl, Ca, and Ti are identified. A systematic error in the estimated temperature due to the impurity lines is evaluated. The contributions from Cl and Ti cannot be neglected in the temperature estimation from a spectrum accumulated through several currentless ECH plasmas in Heliotron E. A removal of those contributions to the temperature estimation is successfully demonstrated. The electron temperature with several percent uncertainty is obtained by PHA every 10 ms during a Heliotron E discharge.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1140668
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  • 10
    Electronic Resource
    Electronic Resource
    Shock compression of powder compacts of CaF2 (1987)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 61 (1987), S. 196-200 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Particle velocity gauges were used to measure the Hugoniots to 30 GPa of CaF2 powder compacts having initial porosities of 15% and 35%. The Hugoniot of the material with 15% porosity is concaved upward over the range to 30 GPa and lies close to the solid Hugoniot in the stress range above 15 GPa. The Hugoniot of the material with 35% porosity becomes an isovolume curve, at about the zero-pressure volume, in the stress range above about 10 GPa. Studies of recovered shock loaded samples indicate that the temperature distributions in the shock-compressed samples were very heterogeneous. It is inferred that the higher stress Hugoniot measurements pertain to a nonequilibrated mixture of the solid and liquid phases of CaF2. In view of this evidence against thermal equilibrium, one may question the validity of the Hugoniot data on the initially porous samples to obtain data on Grüneisen's ratio at high pressures.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.338854
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