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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 63 (1985), S. 613-615 
    ISSN: 1432-1440
    Keywords: Haemoglobinopathy ; Thalassaemia ; Double heterozygoty
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This report concerns a young woman, whose stained blood films revealed a hypochromic and microcytic red cell morphology. It could be shown by haemoglobin analysis that this atypical blood film was due to a double heterozygote disorder of haemoglobin D (Hb D) andβ-thalassaemia. The thalassaemia trait was inherited from her father and the Hb D from her mother. This is the first observation of this rate disorder in a German family. Comparable cases reported in the literature are mentioned.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Marine biology 102 (1989), S. 473-480 
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The calanoid copepods Calanus hyperboreus and C. finmarchicus were investigated in view of their lipid and wax ester content and their fatty acid and alcohol composition. Analyses were performed in females and copepodid stages V and IV from the Fram Strait region between Greenland and Spitsbergen in 1984. This region offers different food conditions like diatom blooms in the North East Water Polynya, food shortage in areas with very close ice cover, high phytoplankton biomass in the marginal ice zone and lower biomass in the open Atlantic water. Lipids contained generally more than 70% wax esters. Highest levels were found in C. hyperboreus with more than 90%. This percentage was not very variable, in spite of large differences in dry weight and lipid content. Copepods with particularly high weight and lipid content were found in the North East Water Polynya. The lightest individuals were found under the pack ice. Lipid proportions per unit dry weight were higher in C. hyperboreus than in C. finmarchicus, whose lowest values were found in the open Atlantic water. Spatial variability in fatty acid composition was much higher than in alcohol composition. The principle alcohols, 20:1 and 22:1, generally accounting for more than 80% of total alcohols. In the North East Water Polynya, the predominant monounsaturated fatty acid was 16:1, while under the ice 20:1 and 22:1 dominated. In the marginal ice zone and in the open water, the 18:4 acid reached percentages up to 30% of total fatty acids. These changes were related to the different food conditions. C. hyperboreus appears to be best adapted to the cold water and unfavourable conditions of polar regions because of its high lipid and wax ester store with long-chain wax esters of high calorific value.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 147 (1988), S. 121-122 
    ISSN: 1432-1076
    Keywords: α-Adrenoceptors ; β-Adrenoceptors ; Phaeochromocytoma ; Catecholamines ; Desensitization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 16-year-old boy is described who had a relapse of a phaeochromocytoma 6 years after an initially successful tumour resection. The relapse was suspected after routine testing of urinary catecholamine excretion and was confirmed by scintigraphy with 123I-meta-iodobenzylguanidine, computed tomography and magnetic resonance imaging. The plasma norepinephrine level was 3082 pg/ml (normal 〈500 pg/ml); the plasma epinephrine level was in the normal range. Surprisingly, our patient had no symptoms, including hypertension. The density of the α- and β-adrenoceptors on circulating blood cells was decreased. Postoperatively the plasma catecholamine levels were in the normal range. Three months after surgery the adrenoceptor density was almost normal. We conclude that the absence of clinical symptoms was probably due to desensitization of the adrenoceptors. After a successful operation to treat phaeochromocytoma, long-term monitoring of catecholamines is necessary to rule out an asymptomatic relapse.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Marine biology 96 (1987), S. 511-518 
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The total lipid and wax ester content as well as the fatty acid and alcohol composition of all copepodid stages and adults of Calanus finmarchicus s.l. were investigated at different locations in the North Sea in 1983 and 1984. Total lipid and the wax ester proportion increased exponentially until Copepodid V. The females were sometimes lower in lipids than the Stage V. The wax ester proportion reached about 90% of total lipids in males and Copepodid V and up to 40% in Copepodid I. The major fatty acids were 16:0, 20:5, and 22:6 and the major fatty alcohols were 16:0, 20:1 and 22:1. At one station the 18:4 acid became one of the dominant acids, because of a Phaeocystis sp. bloom, indicating that the fatty acids of the diet are incorporated mostly unchanged into the lipids of the copepods. The other main fatty acids 20:1 and 22:1 are probably synthesized de novo, serving as precursors for the principal alcohols 20:1 and 22:1. Their levels decreased in the younger stages due to increases in 16:0 alcohol. The fatty alcohol-forming enzyme seems to be specific for saturated and monounsaturated acids, which may be synthesized de novo or derived from diet.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 407 (1986), S. 625-631 
    ISSN: 1432-2013
    Keywords: Guinea pig ; Colon ; Potassium ; Microclimate ; Mucus layer ; Preepithelial barrier
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract K+ concentrations were measured with K+ sensitive liquid ion exchanger microelectrodes in situ and in vitro in the mucus layer at the luminal cell surface of the proximal and the distal colon in guinea pig. In a first series of experiments K+ concentrations were increased in the luminal solution from 0 to 70 mmol·l−1; the serosal K+ concentrations were kept in vitro at 5.4 mmol·l−1. In the proximal colon mean K+ concentration in the microclimate was in vitro 7.9±3.5 mmol·l−1, and independent from mucosal concentrations. In the distal colon in vitro, and in situ in the proximal as well as in the distal colon, K+ concentrations in the microclimate were increased slightly when K+ concentrations were elevated in the luminal solution up to 70 mmol·l−1. In a second series of in vitro studies K+ concentrations were also altered in the serosal fluid. In the proximal and in the distal colon K+ concentrations increased linearily with elevated K+ concentrations in the serosal solutions. A temporarily interrupted mucosal blood flow resulted in a significant increase in the K+ concentration in the microclimate. A paracellular shunt pathway and a high preepithelial diffusion barrier for K+ would explain the observed K+ concentrations in the microclimate at the luminal cell surface.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Molecular biology reports 12 (1987), S. 49-53 
    ISSN: 1573-4978
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract An RNA polymerase III transcript, 7SK nuclear RNA, was found to bear sequence homology to the B2 class of highly repeated elements in the mouse genome. Northern blot hybridizations between the small RNAs and two B2 clones showed that only one of them (p49C8) hybridized to 7SK RNA. Both clones, however, hybridized to 4.5SI RNA as well as to a third class of nuclear RNA transcripts around 170 nucleotides long, whose levels were found to be greatly increased upon induction of transformation in a mouse 3T3 cell line transformed with a temperature-sensitive mutant of simian virus 40.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1434-6079
    Keywords: 33.60.Cv ; 33.80.Eh
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The general properties of the Cooper minimum in molecules are reviewed. Experimental results from synchrotron radiation together with theoretical calculations are presented on both the partial cross sections and angular distribution parameters, β. A detailed examination of HCl is used as an example. Previously unpublished results on CCl n H4−n , CCl n F4−n , ethylene dichloride, I2 and ICl are included. The Cooper minimum is largely discussed as a perturbation from atomic behavior, and is examined as a function of atomic number. The Cooper minimum is also examined as a function of chemical environment. Finally, needs for future research are briefly described.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 2 (1986), S. 327-335 
    ISSN: 1434-6079
    Keywords: 32.80 Dz ; 32.80 Fb
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Autoionization resonances of the type (n−1)d→np, wheren pertains to the outermost shell of Ga, In and Pb, were studied with the use of electron spectrometry in combination with synchrotron radiation. The relative strengths of the exit channels for the various resonance states were measured. In the case of Ga and In, a complete partitioning of the total absorption cross section into thes 2 1 S,sp 1 P, andsp 3 P components (exit channels) was achieved, and in the case of Pb the decay of the resonance states into the major exit channels 6s 2 6p 2 P 1/2, 6s 2 6p 2 P 3/2, 6s 6p 2 4 P 1/2, 6s 6p 2 2 D 3/2 and 6s 6p 2 2 P 1/2 was determined. In Ga, strong coupling was observed for those states of the 4p 2 manifold that have the same symmetries as the final ionic states, e.g. 4p 2 3 P→4s 4p 3 P and 4p 2 1 S→4s 2 1 S. In In, there is a similar, but weaker correlation, which also includes two-electron excitation channels. Comparison between Ga and In shows that thesp 3 P channel is much stronger in In (52% vs 40% in Ga) while thesp 1 P channel is correspondingly weaker (28% vs 37%), with thes 2 1 S channel remaining practically unchanged (20 vs 23%). In Pb, the 6s 2 6P 2 P 1/2 channel displays interference patterns due to a strong, competing direct transition, whereas the other channels do not, indicating population predominantly via the resonance states.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 2 (1986), S. 123-126 
    ISSN: 1434-6079
    Keywords: 32.80-t
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Partial cross sections σ and angular distribution parameters β have been measured for the 4d electrons of atomic tin between 35 and 115 eV. Our data for tin (Z=50) are compared with relativistic-random phase approximation (RRPA) calculations on the closed-shell atom cadmium (Z=48). Satisfactory agreement is found if the results are normalized to the same photoelectron energy. Comparison with RRPA calculations made for palladium (Z=46) and xenon (Z=54) reveals some differences. Other experimental data for the β parameter are in good agreement with our values.
    Type of Medium: Electronic Resource
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