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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 76 (1988), S. 46-54 
    ISSN: 1432-0533
    Keywords: Polyradiculoneuritis ; Protozoa ; Schwann cell destruction ; Axon degeneration ; Dog
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Four pups in a litter of eight Labrador Retrievers suddenly developed hind limb weakness. In three, paralysis ascended rapidly resulting in quadriplegia, cervical weakness, dysphagia and death. Postmortem examination revealed a severe polyradiculoneuritis in which roots, ganglia, and spinal and cranial nerves were heavily infiltrated by lymphocytes, plasma cells and macrophages and contained abundant protozoan pseudocysts. On sections of the brain and spinal cord protozoa were less frequent and appeared independent of the glial nodules which marked focal areas of necrosis. The organisms innitially were thought to beToxoplasma gondii, but this supposition was not supported by serological, immunocytochemical, or electron microscopic findings. Ultrastructurally the organisms resembled an unidentified sporozoan parasite, which has been reported in the CNS of dogs in Scandinavia. The inflamed spinal roots contained many degenerated and demyelinated axons. Electron microscopic studies indicated that the tachyzoite-like organisms, through their invasive and proliferative activities, brough about many of the degenerative changes in the Schwann cells and axons of the spinal roots and nerves.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1437-3262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Abstract Manganese nodules from the Kane Gap (a deep sea channel connecting the Sierra Leone and Gambia Basins off West Africa) were investigated chemically and dated by10Be along cross-sections. Comparing the nodule structure with the stratigraphy of the related sediments, the following conclusions are drawn concerning the sedimentation processes during the last 4 to 6×106 years: The growth of the nodules started about 4 to 4.5 Ma before present during or near to the end of a period of erosion on a fossil-free, probably Miocene sediment. During the first phase of only a few hundred thousandyears, the nodules grew very quickly (7 to 〉18 mm/Ma). Fe-rich hydrogenetic material formed the internal sections of the nodules during this time. Slowing down of the bottom currents, resulting in deposition of thin sediment covers for short intervals, caused the character of the nodules to change to a more diagenetic composition. The growth rates were reduced to about 1 to 2 mm/Ma. The time of slowing is roughly 3 to 4 Ma BP. Probable uncertainties of the dating and growth rates resulting from supposed changes of the10Be supply to the nodules due to variations of the near bottom environment are discussed.
    Abstract: Résumé Le «Kana Gap» est un chenal sous-marin qui relie les bassins de Sierra Leone et de Gambie, au large de l'Afrique occidentale. Des nodules de manganèse, recueillis le long de profils transversaux dans ce chenal, ont fait l'objet d'une étude chimique et d'une détermination d'âge10Be. La comparaison entre la structure des nodules et la stratigraphie des sédiments sous-jacents permet de tirer les conclusions suivantes relatives au processus sédimentaire au cours des 4 à 6 derniers Ma. La croissance des nodules a commencé il y a environ 4 à 4,5 Ma pendant ou juste après un épisode d'érosion sous-marine sur des sédiments non fossilifères, probablement miocènes. Au cours d'une première phase d'une durée de quelques centaines de milliers d'années, la croissance a été très rapide (7 à 〉 18 mm par Ma) avec formation de la partie centrale du nodule, constituée de matière hydrogénée riche en Fe. Ensuite, après ralentissement des courants de fond et dépôt probable d'une mince couche de sédiment, le caractère des nodules a évolué vers une composition plus diagénétique, avec réduction du taux de croissance à 1 à 2 mm par Ma. Le moment de ce changement de régime doit se situer entre 3 et 4 Ma. Des changements dans les conditions de milieu sur le fond de la mer pourraient avoir provoqué une variation de la quantité de10Be apportée aux nodules, d'où résulterait une incertitude sur l'estimation des âges et du taux de croissance; cette question est discutée par les auteurs.
    Notes: Zusammenfassung An Manganknollen aus der Kane-Lücke, dem Verbindungskanal zwischen Sierra Leone Becken und Gambia Becken (vor W-Afrika) wurden entlang Querprofilen durch mehrere Knollen chemische Untersuchungen und10Be Altersbestimmungen durchgeführt. Durch Vergleich des Aufbaus der Knollen mit der Stratigraphie des unterlagernden Sediments werden Rückschlüsse auf Veränderungen des Sedimentationsgeschehens während der letzten 4–6×106 Jahre gezogen. Hiernach begann das Wachstum der Knollen vor maximal 4.5×106 Jahren während oder gegen Ende einer Erosionsphase auf fossilfreiem, vermutlich miozänem Sediment. Während der ersten Phase wuchsen die Knollen über wenige 100000 Jahre sehr schnell (7 bis〉18 mm/106 Jahre). Hierbei schied sich Fe-reiche Knollensubstanz hydrogener Zusammensetzung ab. Nach Verringerung der Strömung und vermutlich zeitweiser Bildung von dünnen Sedimentschleiern änderte sich der Charakter der Knollen zu mehr diagnetischer Zusammensetzung bei wesentlich reduziertem Wachstum (ca. 1 bis 2 mm/106 Jahre). Der Zeitpunkt der Umstellung ist nur sehr grob zu ermitteln, er dürfte etwa zwischen 3 und 4×106 Jahren vor heute liegen. Eventuelle Unsicherheiten bei der Datierung und den Wachstumsraten, die möglicherweise aus milieubedingten Änderungen in der10Be Versorgung der Knollen resultieren, werden diskutiert.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A nearly continuous record of the concentration of 10Be from ice-core data is compared with the tree-ring-derived record for 14C over the same period and it is found that short-term trends in these data sets provide a record of solar activity. No definitive ...
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 340 (1989), S. 550-552 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Existing methods of dating old ice are radiocarbon dating of trapped CO2 and uranium-series dating of dust embedded in the ice1. Radiocarbon dating is possible to only about 25,000 yr, presently requires about 5 kg of ice, and involves a significant probability of contamination for ice near the ...
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-0894
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract In this paper we present accelerator radiocarbon measurements on hand picked benthic and planktonic foraminifera separated from two deep sea cores raised from the South China Sea. From the benthic-planktonic age differences we are able to place limits on the extent to which the ventilation rate of the deep Pacific Ocean has changed over the last 12000 years. While much work remains to be done before any definitive answers for the global oceans can be given, these results on cores with sedimentation rates suitably high to avoid major corrections for bioturbation effects suggest that the ventilation rate of the deep Pacific Ocean has remained nearly the same throughout Holocene time. Further, there is no suggestion that the rate was slower during the period of major glacial retreat. These results confirm that the changes in atmospheric14C/C ratio over the last 10000 years owe their origin to radiocarbon production rate changes.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Planta 179 (1989), S. 228-234 
    ISSN: 1432-2048
    Keywords: ATP-sulfurylase-adenosine 5′-phosphosulfate sulfotransferase ; Pisum (sulfate reduction) ; Proplastid ; Sulfite reductase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The localization of enzymes of assimilatory sulfate reduction was examined in roots of 5-d-old pea (Pisum sativum L.) seedlings. During an 8-h period, roots of intact plants incorporated more label from 35SO 4 2- in the nutrient solution into the amino-acid and protein fractions than shoots. Excised roots and roots of intact plants assimilated comparable amounts of radioactivity from 35SO 4 2- into the amino-acid and protein fractions during a 1-h period, demonstrating that roots of pea seedlings at this stage of development were not completely dependent on the shoots for reduced sulfur compounds. Indeed, these roots contained activities of ATP-sulfurylase (EC 2.7.7.4), adenosine 5′-phosphosulfate sulfotransferase, sulfite reductase (EC 1.8.7.1) and O-acetyl-l-serine sulfhydrylase (EC 4.2.99.8) at levels of 50, 30, 120 and 100%, respectively, of that in shoots. Most of the extractable activity of adenosine 5′-phosphosulfate sulfotransferase was detected in the first centimeter of the root tip. Using sucrose density gradients for organelle separation from this part of the root showed that almost 40% of the activity of ATP-sulfurylase, adenosine 5′-phosphosulfate sulfotransferase and sulfite reductase banded with the marker enzyme for proplastids, whereas only approximately 7% of O-acetyl-l-serine sulfhydrylase activity was detected in these fractions. Because their distributions on the gradients were very similar to that of nitrite reductase, a proplastid enzyme, it is concluded that ATP-sulfurylase, adenosine 5′-phosphosulfate sulfotransferase and sulfite reductase are also exclusively or almost exclusively localized in the proplastids of pea roots. O-Acetyl-l-serine sulfhydrylase is predominantly present in the cytoplasm.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 75 (1988), S. 869-874 
    ISSN: 1432-2242
    Keywords: Auxin ; Auxotrophs ; BUdR ; Enrichment ; Temperature sensitivity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary A protocol has been developed for the negative selection of plant auxotrophs using the nucleoside analogues BUdR and FUdR. The protocol was optimised using nitrogen-starved protoplast-derived cells of Nicotiana plumbaginifolia to simulate auxotrophy. The present results represent a significant improvement over previous reports in that: 1) The background of colonies escaping BUdR/FUdR kill is low and reproducible. 2) The protocol was improved to the point where background survival was 0.03% for non-starved cultures and 0.09% for auxin-starved cultures. 3) It was shown that UV irradiation decreases BUdR sensitivity of dividing cells and that this is overcome by increased exposure to BUdR. 4) Application of the method to auxin-starved haploid protoplast-derived cell suspensions resulted, for the first time, in the selection of temperature-sensitive (ts) auxin auxotrophs. 5) It could be demonstrated, for the first time, that the method in practice enriches for auxotrophs, in this case by a factor of 10 for auxin auxotrophs and at least 60 for ts auxin auxotrophs.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Skeletal radiology 17 (1988), S. 251-254 
    ISSN: 1432-2161
    Keywords: Rib gaps ; Skeletal anomalies ; Chromosome 8 ; Mosaicism ; Partial trisomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Gaps in the first ribs were observed in two children, one with partial and the other with mosaic trisomy for chromosome 8. The sign may be considered in conjunction with other features as a relative indication for chromosomal studies.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Rapid Communications in Mass Spectrometry 3 (1989), S. 62-66 
    ISSN: 0951-4198
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: A new hybrid mass spectrometer of BEQiQu geometry (B, magnetic sector; E, Electric sector; Qi, quistor; Qu, quadrupole mass filter) is described. The high resolution stage (BE) is coupled to a quistor via a series of deceleration lenses, and this is followed by a mass-analysing quadrupole. This configuration enables the storing of ions, investigation of their gas-phase chemistry and the subsequent identification of the resulting fragment or product ions.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Rapid Communications in Mass Spectrometry 3 (1989), S. 417-419 
    ISSN: 0951-4198
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: A simple and efficient deceleration system for the coupling of magnetic and electric sector instruments to quadrupole analyzers is described. The trasnsmission efficiency of the system appears to be at least 80% or better as the ions are decelerated from 3 ke V to 30 eV (a deceleration factor of 1:100). No mass discrimination was observed in the range up to mass 1000.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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