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  • 1
    ISSN: 1432-0533
    Keywords: Neonatal adrenoleukodystrophy ; Peripheral nerve ; Inclusion body
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The pathological findings for a sural nerve biopsy specimen in a case of neonatal adrenoleukodystrophy are described. The density and total number of myelinated fibers in the patient showed no significant changes compared with controls. On electric microscopy, however, thickness of the myelin was smaller in the patient than in controls. Some linear or trilamellar inclusion bodies were found in Schwann cells and fibroblasts, similar to those found in X-linked adrenoleukodystrophy. Büngner's bands were also seen on electron microscopy, and myelin ovoids and balls were seen in teased fibers. These results show that a sural nerve biopsy is useful for the diagnosis of neonatal adrenoleukodystrophy. We suspect that axonal or neuronal degeneration occurs with changes in myelin in neonatal adrenoleukodystrophy.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 61 (1987), S. 4163-4166 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A novel method for detecting the polishing process end point was developed for thin-film heads to achieve a gap depth (throat height) of smaller than 1.5 μm. Special thin-film heads whose magnetic paths are closed at the front end of the gap films were used. As the throat height of these gap films are much the same as the maximum tolerable value of the gap depth, the end point can be detected by monitoring the opening of the magnetic paths of the thin-film head themselves. Electrical detection of the opening was studied, utilizing the bias current dependence of the head inductance. Both inductance values of the head, with and without the bias current, Lb and Lnb, change when the magnetic path opens. The Lnb and Lb values at 3-mA bias current are 250 and 95 nH for the head having a closed magnetic path, and 180 and 155 nH for an open one, respectively. The difference Lnb−Lb decreases to about 1/6 when the magnetic path is opened. An apparatus was developed to measure the amplitude of Lnb−Lb. It utilizes a Wheatstone bridge circuit, excited with a 10-MHz sinusoidal signal for measuring inductance, and a 0.2-Hz rectangular pulse train as a bias current, respectively. Experimental results indicate that polishing can be stopped within 0.6 μm of the front edge of the gap films.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1920
    Keywords: Ultrasonography ; Spinal cord ; Spinal canal
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The normal development of the spinal cord from the fetal period to infancy was studied by ultrasonography (US) with a 7.5 MHz transducer. Longitudinal and transverse sections of the spinal cord were clearly observed. The sagittal and transverse diameters of the spinal cord increased with age. In order to evaluate disorders of the spinal cord precisely, it is necessary to clarify the normal features as well as the normal development of the spinal canal and cord, and the surrounding structures. US with such a high frequency transducer will be the most suitable for this purpose.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1920
    Keywords: Trisomy 18 ; Trisomy 13 ; Brain imaging ; Neuropathology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A comparative study of intracranial imaging and brain pathology in cases of trisomy 18 and 13 was performed. Computed tomography (CT) and ultrasonography (US) revealed disproportional dilatation of the lateral ventricles, a wide Sylvian fissure and a large extracerebellar space with a small cerebellum in each case. In addition, it was characteristic that the occipital poles of the cerebrum protruded in the infero-posterior direction in trisomy 18, and the pontine basis was relatively wide in trisomy 13. The brain pathology in trisomy 18 and 13 demonstrated that the large extracerebellar space is due to the cerebellar dysplasia and protruding occipital poles, the wide Sylvian fissures due to the temporal lobes or external capsular dysplasia, and the relatively wide pontine basis due to meningeal glioneuronal heterotopia. Thus, the characteristic intracranial image in trisomy 18 and 13 suggest microdysgenesis of the brain and might be useful for understanding the pathological structure of the central nervous system in these conditions.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Surgical endoscopy and other interventional techniques 2 (1988), S. 205-208 
    ISSN: 1432-2218
    Keywords: Oesophagoscopy ; Oesophageal carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The endoscopic findings and the surgical results of 131 resected cases of superficial oesophageal cancer are described. Of these 131 cases 24 (18%) had mucosal cancer. Twenty-one (88%) of 24 cases of mucosal cancer of the oesophagus had neither nodal involvement nor vascular invasion, and therefore excellent long-term results can be anticipated. In order to obtain good results in the treatment of mucosal cancer of the oesophagus, the role of oesophagoscopy is extremely important in the early diagnosis of this cancer.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1920
    Keywords: Computed tomography ; Ventricular dilatation ; Colpocephaly ; Brain damage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cranial computed tomography (CT) of 108 cases with dilated lateral ventricles was reviewed to elucidate the relationship between focal vulnerability of developing brain and disproportional dilatation of lateral ventricles. CT findings of 108 cases with symmetrical dilatation of lateral ventricles were classified into three types by morphometry of lateral ventricles: anterior horn predominant type (31 cases), diffuse type (36 cases), posterior horn predominant type (41 cases). Posterior horn predominant type has a tendency to occur in congenital anomalies and premature brain damage, and anterior horn predominant type in infantile brain damage. This disproportional dilatation of anterior or posterior horns suggests a vulnerability of periventricular structure in developing brain.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-1920
    Keywords: Ultrasonography ; Ventricular asymmetry ; Neonate ; Premature infant
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Ultrasonographic examination was performed in 13 preterm, 10 normal term and 3 term brain-damaged infants to evaluate changes of the ventricular width with the head position. The lower side of the frontal horn was narrowed and the upper side dilated in all preterm and brain-damaged infants. These changes of the ventricular width may be due to gravity and soft brain. Therefore, it is very important to consider the transformation of the lateral ventricles with the head position when asymmetry of the lateral ventricle is identified in infants showing prematurity or brain damage.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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