Digitale Medien
Oxford, UK
:
Blackwell Publishing Ltd
Clinical & experimental allergy
11 (1981), S. 0
ISSN:
1365-2222
Quelle:
Blackwell Publishing Journal Backfiles 1879-2005
Thema:
Medizin
Notizen:
The migration velocity and morphology of basophils in vitro were examined after the addition of anti-immunoglobulin (anti-lgE or anti-IgG). In atopic asthma patients with high serum IgE levels (more than 1000 i.u./ml) basophils showed increased migration velocity and showed pear-shaped and palmate processes after the addition of anti-lgE, but on the addition of anti-IgG, these basophils did not show increased migration velocity or morphological changes. In intractable asthma patients with low serum IgE levels, these changes occurred with anti-IgG but not with anti-IgE. These in vitro findings suggest a basophil reactivity to anti-IgE and anti-IgG in individual patients and support our previous differentiation of asthma patients according to basophil reaction.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1111/j.1365-2222.1981.tb01563.x
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