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  • 2000-2004  (1)
  • 1980-1984  (3)
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  • 1
    Electronic Resource
    Electronic Resource
    Diet in late pregnancy and glucose-insulin metabolism of the offspring 40 years later (2000)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 107 (2000), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To determine how diets of women in pregnancy influence the glucose-insulin metabolism of their offspring in adult life.Design A follow up study of men and women born during 1948–1954 whose mothers had taken part in a survey of diet in late pregnancy.Setting Aberdeen, Scotland.Population One hundred and sixty-eight men and women born in the Aberdeen Maternity Hospital.Main outcome measure Plasma glucose and insulin concentrations, fasting and after a standard oral glucose challenge.Results The offspring of women who had high intakes of fat and protein in late pregnancy had a reduced plasma insulin increment between fasting and 30 min with a 7.0% decrease in increment (P= 0.007) per 10 g increase in protein intake and a 4.9% decrease (P= 0.002) per 10 g increase in fat intake. This was independent of the mother's body mass index or weight gain in pregnancy. A low maternal body mass index in early or late pregnancy was associated with a raised fasting plasma insulin concentration with a decrease of 2.4% (P= 0.05) per 1 kg/m2 increase of maternal body mass.Conclusion High intakes of protein and fat during pregnancy may impair development of the fetal pancreatic beta cells and lead to insulin deficiency in the offspring. The offspring of thin mothers tend to be insulin resistant.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.2000.tb11088.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Beta-human chorionic gonadotrophin levels before and after the development of pre-eclampsia (1984)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 91 (1984), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. Maternal serum levels of beta-human chorionic gonadotrophin ((β-hCG) concentrations were significantly higher in 41 primigravid patients with proteinuric pre-eclampsia compared with those in 41 primigravid normotensive women matched for age and gestation. β-hCG was also measured in serial serum samples obtained from 13 women who had a high weight-gain between 20 and 30 weeks of pregnancy. Seven of these pregnancies were subsequently complicated with pre-eclampsia while the remaining six continued to be normotensive; β-hCG levels were found to rise before the clinical signs of pre-eclampsia appeared.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1984.tb04848.x
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Blood levels of proteinase inhibitors in pregnancy (1982)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 89 (1982), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. Plasma volume, serum α2-macroglobulin, α1-antitrypsin, Cï inactivator and α2-antiplasmin, and plasma antithrombin III were measured in 10 pregnant women at gestation periods of 12–14 and 37–38 weeks. The proteinase inhibitors were also measured in 10 non-pregnant healthy women. There was a significant increase in the α1-antitrypsin concentration and significant decreases in α2-macroglobulin and Cï inactivator, but the total circulating quantity of all the proteinase inhibitors was significantly increased.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1982.tb03615.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Blood levels of proteinase inhibitors in pre-eclampsia (1983)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 90 (1983), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. The blood levels of α2-macroglobulin, α1-antitrypsin, CT inactivator, antithrombin III and α2-antiplasmin were measured in 18 primigravidae with moderate or severe pre-eclampsia and in 18 gestation-matched primigravidae with uncomplicated pregnancy. The mean levels of the proteinase inhibitors did not differ between the pre-eclampsia and uncomplicated pregnancy groups.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1983.tb06768.x
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    Paper (German National Licenses)
    Fulltext
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