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Digitale Medien

Cathepsin-B activity in otosclerosis (1983)

Ribári, O. ; Sziklai, I. ; Kiss, J. G. ; [weitere]

Springer

European archives of oto-rhino-laryngology and head & neck 238 (1983), S. 123-125

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Details

ISSN: 1434-4726

Schlagwort(e): Otosclerosis ; Stapes footplate ; Cathepsin B

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary Cathepsin-B activity was determined fluorimetrically in the otosclerotic stapes footplate, the stapes superstructure, normal temporal cortical bone, and os frontale osteoma. Measurements with a synthetic substrate made determinations in individual samples possible. The cathepsin-B activity in the otosclerotic stapes footplate was one order of magnitude higher than that of the superstructure, which was not affected by the disease. The cortical bone and the superstructure displayed similar activities, as did os frontale osteoma and otosclerosis. The high lysosomal proteinase activity appears to be closely connected to the otosclerotic bone resorption process.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00454303

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