ISSN:
1435-0130
Keywords:
Cellular aging
;
Scar-derived fibroblasts
;
Cell culture
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary This study was performed employing cytogerontologic analysis to investigate the in vitro proliferative capacity of the fibroblasts of scar and normal dermis obtained from the same individual. Scarderived fibroblasts had a shorter in vitro lifespan, longer cell population doubling time, diminished cell numbers at confluency and lower percentages of cell able to incoporate 3H-thymidine than comparable firoblasts derived from normal dermis. These results may indicate that the growth characteristics of scar-derived fibroblasts resemble those of late-passage levels of normal dermal fibroblasts.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00266805
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