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  • 1
    Electronic Resource
    Electronic Resource
    Diffusion coefficients of anticancer drugs and compounds having a similar structure at 30 °C (1983)
    Springer
    Colloid & polymer science 261 (1983), S. 70-73 
    Details
    ISSN: 1435-1536
    Keywords: Diffusion coefficient ; Anticancer drug ; Uracil ; Diffusion cell method and Uridine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The measurement of the diffusion coefficients of anticancer drugs and compounds having a similar structure in aqueous solution at 30 °C are carried out and the effect of some groups affecting the diffusion coefficients is investigated. The measurements of viscosity are also carried out in order to obtain the viscosity coefficient. The radius of molecule from the diffusion coefficients is in agreement with the value from the viscosity measurements. Under the concentration range studied, it seem that these compounds have a same state, for example, monomer or dimer. However, from Van der Waals radius of the results obtained, these solutes are monomer state. In spite of a large size, the diffusion coefficient of Uridine-5′-monophosphoric acid indicates a high value because of the potential gradient occurs in diffusion. From the result, 5-fluoro-2′-deoxy-5′-monophosphoric acid diffuses quickly in human body in spite of the large molecular weight.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01411520
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  • 2
    Electronic Resource
    Electronic Resource
    Interaction of 5-fluorouracil (anticancer drug) and sodium poly-α, L-glutamate (1980)
    Springer
    Colloid & polymer science 258 (1980), S. 111-111 
    Details
    ISSN: 1435-1536
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01474966
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  • 3
    Electronic Resource
    Electronic Resource
    Interaction of 5-trifluoromethyluracil with sodium poly-α,L-glutamate (1983)
    Springer
    Colloid & polymer science 261 (1983), S. 467-470 
    Details
    ISSN: 1435-1536
    Keywords: 5-trifluoromethyluracil ; Sodium poly-α,L-glutamate ; Interaction ; Viscosity ; 1-(2-tetrahydrofuryl)-5-fluorouracil
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The purpose of our research is to obtain an understanding of the binding mechanism and to the correlations in term of chemical structure and the potentiactive drug activity. The interaction of 5-trifluoromethyluracil (although 5-trifluoromethyluracil do not used as anticancer drug, the structure of the compound has similar structure with 5-fluorouracil) with sodium poly-α,L-glutamate in aqueous solution was studied with a spectral method and viscosity measurement. From the binding data, the molar change in enthalpy, entropy and the number of binding sites on polymer were calculated. It is very interesting that the value ofδH
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01419829
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  • 4
    Electronic Resource
    Electronic Resource
    Studies of optical properties of acridine orange-sodium cellobiose sulfate complex (1980)
    Springer
    Colloid & polymer science 258 (1980), S. 447-450 
    Details
    ISSN: 1435-1536
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Zusammenfassung Aus Untersuchungen des Zirkulardichroismus und der Adsorptionsspektren des Acridin-Orange-Natrium-Cellobiose-Sulfat-Komplexes folgt eine interessante Deutung. Wenn AO in asymmetrischer Umgebung gelagert wird, entsteht intensive Aktivität. AO an Natrium-Cellobios-Sulfat gebunden hat eine starke Tendenz sich aufzurichten und das gebundene AO dürfte die Superhelix bilden.
    Notes: Summary From the studies of the circular dichroism and absorption spectra of acridine orange-sodium cellobiose sulfate complex, we have deduced the following interesting explanation. If AO is situated in an environment which contains centers of asymmetry carbon atoms, it becomes optically active by induction. AO bound sodium cellobiose sulfate has a high stacking tendency and the bound AO may be constituted the superhelix.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01480839
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  • 5
    Electronic Resource
    Electronic Resource
    Interaction of 5-fluorouracil with sodium carboxymethylcellulose (1982)
    Springer
    Colloid & polymer science 260 (1982), S. 511-513 
    Details
    ISSN: 1435-1536
    Keywords: 5-fluorouracil ; Sodium carboxymethylcellulose ; Interaction ; Enthalpy ; Viscosity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The interaction of an anticancer drug, 5-fluorouracil with sodium carboxymethylcellulose in aqueous solution was studied with a spectral method and viscosity measurement. From the binding data, the standard molar change in enthalpy, entropy and the number of binding sites on polymer were calculated. The standard molar change of enthalpy of 5-fluorouracil is about — 7 Kcal/mol with sodium carboxymethylcellulose. The enthalpy change is a considerably greater.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01452998
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  • 6
    Electronic Resource
    Electronic Resource
    Interaction of 1-(2-tetrahydrofuryl)-5-fluorouracil with sodium poly-α,L-glutamate (1981)
    Springer
    Colloid & polymer science 259 (1981), S. 350-353 
    Details
    ISSN: 1435-1536
    Keywords: Anticancer drug ; 1-(2-tetrahydrofuryl)-5-fluorouracil ; Sodium poly-α ; L-glutamate ; Interaction ; Viscosity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Zusammenfassung Die Wechselwirkung zwischen 1-(2-Tetrahydrofuryl)-5-fluorouracil und Na-Poly-α,L-glutamat wurde mit den Methoden der Spektroskopie und der Viskositätsmessung untersucht. Aus den Bindungsdaten wurden die molare Änderung von Entropie und Enthalpie und die Zahl der Brückenstellen des Polymeren berechnet. Der Wert von ΔG° beträgt ca. −10 Kcal/mol. Die Affinität ist also sehr groß.
    Notes: Summary The interaction of an anticancer drug, 1-(2-tetrahydrofuryl)-5-fluorouracil with sodium poly-α,L-glutamate in aqueous solution was studied with a spectral method and viscosity measurement. From the binding data, the molar change in enthalpy, entropy and the number of binding sites on polymer were calculated. The standard affinity of 1-(2-tetrahydrofuryl)-5-fluorouracil is about −10 kcal/ol with sodium poly-α,L-glutamate. The affinity is also very high.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01524715
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  • 7
    Electronic Resource
    Electronic Resource
    Interaction of malachite green or acridine orange and sodium poly-a,L-glutamate (1981)
    Springer
    Colloid & polymer science 259 (1981), S. 774-774 
    Details
    ISSN: 1435-1536
    Keywords: Malachite green ; acridine orange ; Na-poly-a ; L-glutamate ; Interaction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01419326
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  • 8
    Electronic Resource
    Electronic Resource
    Liner and nonlinear elastic analysis of cracked plate: Application of a penalty function and superposition method (1981)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 17 (1981), S. 719-733 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: Cracked plates of power hardening material under plane strain and incompressibility conditions are investigated in this work by using a penalty function and superposition method. The present numerical method is found to be quite efficient for the relevant problems if the hardening exponent of material is not so large.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620170506
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