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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 232 (1981), S. 651-652 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 231 (1982), S. 315-320 
    ISSN: 1432-0711
    Keywords: Ovarian cycle ; Physiology ; Catecholestrogens ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Using highly stabilized catecholestrogen preparations-ascorbic acid added to the free alcohols or benzoic acid derivatives — 2- and 4-hydroxyestrogens were tested in simple, clearly defined animal models: As index for the peripheral action the influence on vaginal opening and uterus weight gain was monitored after continuous s.c. administration for 6 days (minipumps) in immature intact rats resulting in a relative estrogenic potency (estradiol = 100%) of 70–100% for 4-hydroxyestradiol and less than 30% for 2-hydroxyestradiol. As index for the central action LH levels were measured in adult ovx rats leading to the same relations in the relative potencies. As index for both central and peripheral actions LH levels and the formation of corpora lutea were investigated in animals with an intact but prepubertal feed-back loop, i.e. in 25-day-old immature rats. 4-Hydroxyestradiol in this model clearly triggered LH surges and induced ovulations, its potency being in the same range as that of estradiol. 2-Hydroxyestradiol, in comparable doses, again showed no significant effect. Finally, female immature animals known to ovulate 3 days after PMS injection were treated concomitantly with either primary or catecholestrogen-antibody preparations. Whereas the primary estrogen antibody significantly blocked ovulation, the 2- and 4-hydroxyestrogen antibodies were ineffective. If, however, PMS and estrogen-antibody treated animals were supplemented with 4-hydroxyestrogens, ovulations could be restored. Thereby, it was inferred that peripheral 4-hydroxyestrogens, though not essential for the physiology of reproduction, can completely replace the physiologically essential peripheral estradiol at central target sites.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 311 (1984), S. 50-53 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The extent of leaching was assessed by measuring the nitrate content of samples of soil or chalk removed in successive 0.33 m increments to a depth of 8 m below an experimental site at Hurley, Berkshire, UK. Management of the site is summarized in Table 1. The site was on a loam of the Frilsham ...
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Plant and soil 76 (1984), S. 23-33 
    ISSN: 1573-5036
    Keywords: Ammonia volatilization ; Denitrification ; Grazed grassland ; Leaching ; N balance ; N losses ; Soil total N
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary Most studies of N relationships in grassland have used cut swards. These have shown that for annual inputs of 200 to 400 kg N/ha from fertilizer or fixation, 55 to 80% of the N is recovered in harvested herbage. Generally, no more than 5 to 15% is lost through leaching and denitrification with most of the remaining N incorporated into soil organic matter. The relatively high efficiency of N use by cut swards reflects rapid uptake of N and the removal of a large part of the input in herbage. Inclusion of the grazing ruminant alters the efficiency of N use; only 5–20% of the input is recovered in meat or milk, and 75 to 90% of the N ingested is excreted, mainly as urea in urine. Application of N in urine ranges from 30–100 g/m2. Too much N is voided for effective recovery by the sward whilst soils usually contain insufficient C to allow appreciable immobilization. The surfeit is lost. Hydrolysis of urea is usually complete within 24 h of urine deposition. For urine-treated pasture in New Zealand (NZ) losses by NH3 volatilization of up to 66% of applied N are found during warm dry weather, with an average of 28% for a range of seasonal conditions. In the UK, the average rate of NH3 loss from an intensively grazed ryegrass sward was 0.75 kg N/ha/day during a 6-month season. NH 4 + remaining in the soil may be nitrified, nitrification being complete within 3 to 6 weeks. Although some NO 3 − is recovered by plants, a substantial portion is leached and/or denitrified. On average such losses were 42%, with only 30% of the added N recovered by plants in urine-treated pasture in NZ. In the UK annual leaching of 150 to 190 kg N/ha has been observed for grazed swards receiving 420 kg N/ha/yr. Low retention of N by grazing ruminants results in a breakdown of N relationships in intensively managed grasslands. The substantial losses through NH3 volatilization, leaching and denitrification have serious agronomic, economic and environmental implications.
    Type of Medium: Electronic Resource
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