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Morphine eye-drops reduce homatropine induced mydriasis in man (1984)

Fanciullacci, M. ; Cangi, F. ; Gatto, G. ; [et al.]

Springer

Cellular and molecular life sciences 40 (1984), S. 731-733

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ISSN: 1420-9071

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary In 7 healthy volunteers 4% morphine eye-drops, when administered to one eye, caused a miosis limited to that eye. In 7 other healthy volunteers morphine was administered into one eye after bilateral instillation of 0.5% homatropine opthalmic drops; the eye treated with morphine and homatropine showed a mydriasis less intense than the other eye treated only with homatropine. It is suggested that topical morphine locally affects sympathetic function by inhibiting noradrenaline release into the iris neuromuscular junction.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01949747

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