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  • 1980-1984  (3)
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Materialart
Erscheinungszeitraum
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  • 1
    Digitale Medien
    Digitale Medien
    Langerhans’cells in human cervical epithelium: effects of wart virus infection and intraepithelial neoplasia (1983)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 90 (1983), S. 0 
    Details
    ISSN: 1471-0528
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Summary. The distribution of Langerhans’cells and T and B lymphocytes in cervical epithelium affected by wart virus infection (WVI) and intraepithelial neoplasia (CIN) has been studied by immunohistological techniques with a panel of monoclonal antibodies. In comparison with normal tissue epithelium infected by wart virus consistently showed a partial depletion or absence of both Langerhans’cells and T lymphocytes. The few Langerhans’cells which remained showed loss of their normal dendritic processes and were confined to the vicinity of the basement membrane. In contrast, epithelium from patients with CIN showed an increase in spindle-shaped Langerhans’cells associated with increased numbers of stromal and intraepithelial lymphoid cells. These findings suggest that there is a marked difference in host immune responses in these two conditions and may explain why WVI tends to persist in the epithelium while CIN is often associated with a lymphoid reaction.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1471-0528.1983.tb08936.x
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Langerhans’cells in human cervical epithelium: an immunohistological study (1983)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 90 (1983), S. 0 
    Details
    ISSN: 1471-0528
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Summary. Langerhans’cells are intraepithelial dendritic cells believed to be important in the recognition and processing of exogenous antigens. They were demonstrated by immunohistological methods in cervical tissue obtained from 10 subjects ranging in age from 30 weeks gestational age to 62 years. Langerhans’cells were clearly delineated in all tissue sections and appear to form a relatively constant component of both the transformation zone and ectocervical epithelium. In addition to Langerhans’cells, a population of T lymphocytes characterized as predominantly T-cytotoxic/suppressor cells have also been demonstrated. The interaction between Langerhans’cells, T lymphocytes and stromal macrophages and their relation to antigen recognition is discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1471-0528.1983.tb08935.x
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    An immunofluorescent study of the ampicillin rash (1982)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 12 (1982), S. 0 
    Details
    ISSN: 1365-2222
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: The aetiology of the ampicillin rash is uncertain although numerous theories have been proposed–mainly immunological. One such concerns the presence of anti-epithelial antibodies which have received conflicting reports in the literature. In this study, skin biopsies from three patients with a maculopapular ampicillin-rash were studied by immunofluorescence to investigate the presence of anti-epithelial antibodies. However immunofluorescence for IgG, IgM, IgA and C3 was completely negative so that we were unable to provide any support for this particular hypothesis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2222.1982.tb02528.x
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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