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  • 1980-1984  (3)
  • 1
    ISSN: 0942-0940
    Keywords: Glioma ; cellular immunity ; immunotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Whereas substantial evidence indicates that the majority of glioma patients make humoral immune responses to their own tumours, the evidence that glioma patients make significant cellular immune responses is more tenuous and controversial. In order to study those properties of human gliomas that might contribute to their ability to escape cell-mediated immune attack, we have examined the ability of cultured human glioma cells to elicit allogeneic cytolytic lymphocyte responses in vitro. Five of ten glioma lines were unable to elicit allogeneic cytolytic lymphocyte responses in mixed lymphocyte-tumour cultures, despite the presence of serologically detectable alloantigens on the surface of the glioma cells. Analysis of the reasons why certain glioma lines failed to stimulate cytolytic lymphocyte responses revealed three distinct mechanisms by which human gliomas may escape cellular immune attack: 1. a defect in immunogenicity which can be overcome by “help” from an allogeneic mixed lymphocyte reaction, 2. the secretion of a protective mucopolysaccharide coat, and 3. the production of macromolecular immunosuppressive substance(s). The implications of these findings for the immunotherapy of human gliomas are discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 109 (1983), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 517 (1984), S. 207-214 
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Preparation of Arsenic Chloridetetrafluoride, AsClF4, and Spectroscopical Interpretation of the Series AsClnF5-nDuring the pyrolysis of [AsCl4]+[AsF6]- AsClF4 is formed in preparative amounts under suitable conditions. The I.R.-matrix and Low-Temperatur-Raman Spectrum are reported.In the series AsClnF5-n exists a linear context between the average valence frequency 1/5 Σνval and the sum of the electronegativities of the ligands.
    Notes: Die Pyrolyse von [AsCl4]+[AsF6]- führt unter geeigneten Bedingungen zur Bildung präparativer Mengen von AsClF4, dessen IR-Matrix- und Tieftemperatur-Ramanspektrum angegeben wird.In der Reihe AsClnF5-n besteht ein linearer Zusammenhang zwischen der mittleren Valenzschwingungsfrequenz 1/5 Σνval und der Elektronegativitätssumme der Liganden.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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