ISSN:
0021-8383
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Acylation of Heterocycles with Carbonic Acid Derivatives. II. Endo and Exo Carbamoylation of 2-Amino-benzimidazole Derivatives with Isocyanates. Mechanism of the Acyl Group Migration2-Amino-benzimidazoles react with isocyanates with good yields to give 2-amino-1-carbamoyl-aminobenzimidazoles 1 at -30°C and the corresponding 2-carbamoyl isomeres 2 at room temperature, respectively. The isomerization mechanism was studied by crossover experiments and kinetic measurements and has been found to consist of inter- and monomolecular acyl transfer.
Additional Material:
4 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19823240515
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