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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Biochemistry 21 (1982), S. 729-732 
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Human genetics 〈Berlin〉 57 (1981), S. 394-398 
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Pairs of cultured amniotic cells and maternal fibroblasts (“feto-maternal pairs”) were studied for hexosaminidase A (HXA) and arylsulfatase A (ASA) activity. These lysosomal enzyme activities are genetically deficient in Tay-Sachs disease and metachromatic leukodystrophy, respectively. After HXA was standardized by relating it to hexosaminidase B (HXB) activity, a feto-maternal correlation coefficient of r=0.51 (n=32; 95% confidence limits 0.197–0.73) was found for the HXA/HXB activity quotients. This coefficient was near the 0.5 value theoretically valid for mother-child pairs, suggesting that the studied activities reflect essentially the genetic variability. The studies of ASA revealed a high variability of individual activities, which was reduced in two steps: (1) The ASA activity was related to the mean of two lysosomal reference enzyme activities, total hexosaminidase and acid β-galactosidase. (2) Since the square root of ASA activity was found to follow more closely the variation of the reference activities, the square root of ASA activity over the mean reference activity was taken as a more standardized measure of ASA activity, and the quotient was treated statistically. Positive feto-maternal correlation of standardized ASA activity was obtained after the elimination of three pairs with extreme values. A correlation coefficient of r=0.42 (n=26; 95% confidence limits 0.039–0.695) resulted. The implications of these correlation studies for the problem of heterozygote identification by quantitative enzyme assays in families deficient in HXA and ASA activity were considered.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    International journal of thermophysics 5 (1984), S. 229-238 
    ISSN: 1572-9567
    Keywords: aluminosilicate fibrous insulator ; ceramic fiber ; hot wire method ; thermal conductivity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The temperature and bulk density dependence of the thermal conductivity of commercial aluminosilicate fibrous insulators were studied by using the transient hot wire method. The thermal conductivity of ceramic fibrous insulators in both air and helium gas atmosphere increased with increasing bulk density. At high temperatures, however, the insulators with lower bulk density showed a higher thermal conductivity because of heat radiation. The following experimental relation between thermal conductivity λ and temperature θ was obtained for aluminosilicate fibruous insulators: λ=a exp(bθ). Relationships are given between the constants a and b and the bulk density. From the relation, the optimum bulk density of ceramic fibrous insulators can be calculated for each working temperature.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    International journal of fracture 16 (1980), S. 275-285 
    ISSN: 1573-2673
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Résumé On présente les facteurs d'intensité de contrainte pour une fissure de surface verticale semi-elliptique dans un corps élastique semi-infini soumis à une pression constante sur la surface de la fissure. L'approche utilisée recourt à une intégrale singulière définie uniquement sur la superficie de la fissure, où l'on prend en considération l'affaiblissement de la singularité des contraintes au voisinage des points où la périphérie de la fissure est en intersection avec la surface du corps semi-infini. Cette approche permet d'obtenir les facteurs d'intensité de contrainte au voisinage des points considérés et révèle que le facteur d'intensité des contraintes passe par un maximum en ceux-ci et décroît vers zéro lorsqu'on s'en éloigne.
    Notes: Abstract The stress intensity factors are presented for a vertical semi-elliptical surface crack in an elastic semi-infinite body which is subjected to a constant pressure on the crack surface. The approach utilizes a singular integral equation which is defined over the crack area only, where the weakness of the stress singularity is taken into account near the corner points at which the crack periphery intersects the surface of the semi-infinite body. This pertinent approach provides the proper assessment of the stress intensity factors in the vicinity of the corner points, and reveals that the stress intensity factor reaches a maximum value near the corner point and then decreases to zero as the point is approached.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of inherited metabolic disease 5 (1982), S. 79-80 
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    International journal of fracture 24 (1984), S. R121 
    ISSN: 1573-2673
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of elasticity 14 (1984), S. 155-161 
    ISSN: 1573-2681
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract The asymptotic nature of the elastic field is studied at the point of transition from frictional contact to frictionless contact between two different elastic bodies. The nature depends on the direction of slip, and the singular stress field appears when the body with smaller μ/(κ−1) (μ: the shear modulus, κ=3−4ν, ν: Poisson's ratio) slips towards the region of frictional contact, while no singularities appear when the direction of slip is opposite. The order of the singularity is smaller than 1/2 regardless of the level of friction.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1573-4927
    Keywords: muscle protein ; protein turnover ; protein synthesis and degradation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Fractional rates (% · day−1) of synthesis and degradation were determined by measuring the output of Nτ-methylhistidine (MeHis) in the excreta at 4 and 8 weeks of age in the chicken. At 4 weeks of age, the fractional rate of synthesis of the meat-type stock was twice that of the egg-type stock (White Leghorn), but the fractional rates of synthesis at 8 weeks of age were similar (4.1–5.1% · day−1) among stocks. The fractional rate of degradation (1.3–1.5% · day−1) of the meat-type stock at 8 weeks of age was less than half the rate of the egg-type stock (2.9% · day−1). The fractional rates of synthesis and degradation at 4 weeks of age in the Satsuma native fowl were relatively high compared with those in the other stocks. In particular, the rate of degradation (8.6% · day−1) at 4 weeks of age was approximately twice that of other stocks. These results show that fractional rates of synthesis and degradation of muscle protein in the chicken differ among genetically diverse groups. The effect of changes in rates of synthesis and degradation on the change in fractional growth rate also differed. From regression coefficients (bK s · FGR and bK d · FGR) of these rates in skeletal muscle protein on the fractional growth rate, it was recognized that the change in growth rate accompanies the changes in both synthesis and degradation in White Leghorn and commercial broilers but only the change in synthesis in White Plymouth Rock (dw) and Satsuma native fowl.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 18 (1980), S. 10-18 
    ISSN: 1741-0444
    Keywords: Biolised cardiac prostheses ; Defect and failure ; Device reliability ; Fabrication process ; Inspection system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The clinical application of cardiac prostheses requires a pump that has the highest reliability and no defects. Considering the possibility of clinical implantation in the future, quality control and inspection systems have been incorporated into the fabrication process of biolised cardiac prostheses. Inspection procedures are employed at every strategic point in the pump fabrication process, including visual inspection, dimensional check, material test, performance test and s.e.m. observation. Over the past one-and-a-half years we have inspected 480 components and assemblies from 49 total artificial hearts and left-ventricular assist devices. A total of 93 defects and failures were detected by the inspection system, of which 48 defects were repaired in the fabrication lines. The remaining components were rejected and removed from the pump fabrication lines. The quality of trileaflet dura mater valves was significantly improved by the incorporation of the quality-control system. Since most of the fabrication and assembly are performed manually at the present time, the quality control has contributed greatly to improved device reliability.
    Type of Medium: Electronic Resource
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