ISSN:
0021-9541
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
,
Medicine
Notes:
Cytoplasts prepared from fibroblasts arrested by hydroxyurea were fused with serum-arrested, quiescent fibroblasts. In contrast to unfused mon-nucleated cells in the same culture, a sizable fraction of these cybridoids entered S phase in the absence of extracellular serum stimulation. Because DNA synthesis commenced only after a considerable lag following fusion, it was concluded that the cytoplasts contain factors which initiate the progression of quiescent cells toward S phase.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jcp.1041100315
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