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  • 1
    ISSN: 1432-1106
    Keywords: Medial forebrain bundle ; Ascending components ; Descending components ; HRP ; Sensitive substrate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The ascending and descending components of the medial forebrain bundle (MFB) were investigated by means of horseradish peroxidase (HRP) with a sensitive substrate. The HRP was injected iontophoretically into the MFB at various levels from the anterior commissure to the posterior hypothalamus. In order to prevent the diffusion of HRP to other brain areas, a double micropipette system was used. The descending components of the MFB are derived from (1) the anterior cingulate area, infra- or prelimbic area, and sulcal cortex, (2) the lateral septal nucleus and diagonal band, (3) the bed nucleus of the stria terminalis, (4) the paraventricular nucleus (5) the substantia innominata, (6) the amygdaloid complex (AM), (7) the ventromedial (VM) and dorsomedial (DM) hypothalamic nuclei, (8) the entopeduncular nucleus and (9) nucleus periventricularis stellatocellularis. The ascending components of the MFB originate in: (1) the medial preoptic nucleus, (2) the nucleus periventricularis stellatocellularis and rotundocellularis, (3) the posterior hypothalamic nucleus, (4) the parafascicular nucleus, (5) the ventral premammillary nucleus, (6) the substantia grisea periventricularis, (7) the lateral habenular nucleus, (8) the VM and DM, (9) the paratenial nucleus, (10) the AM and (11) the arcuate nucleus.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 8 (1981), S. 0 
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Seven different alloantisera absorbed with red blood cells (RBC) from appropriate strains of rats detected a series of B cell alloantigenic specificities that could be divided into two groups, presumably coded for by at least two different closely-linked loci in the rat major histocompatibility complex (MHC), RT1. The one locus had two allele codes for a broad specificity and the other locus codes for a unique specificity that was found only in the restricted strains of rats that shared the same mixed lymphocyte reaction (MLR) phenotype. RBC-absorbed alloantisera were monitored against a panel of B cell fractions obtained from sixteen inbred strains. Two alloantisera, ACI anti-W and W anti-TO detected two broad specificities, into either of which all inbred strains tested were classified. Two broad RT1-B region-associated specificities were thus designated provisionally as Ba-1.1 and -1.2. Another five alloantisera detected four respective specificities which have a narrower strain distribution. Sixteen inbred strains were classified into one of five specificities detected by W anti-F344, F344 anti-SDJ, WKA anti-ACI, W anti-BUF and ACI anti-W absorbed with LEJ lymph node cells. Each specificity was designated provisionally as Ba-2.1, -2.2, -2.4, -2.6, -2.7, respectively. A complete association of Ba-2 specificities with MLR phenotype was observed. Antigenic specificities of Ba-2.1, -2.2 and -2.4 were all classified in a group of Ba-1.1 specificity, whereas Ba-2.6 and -2.7 specificities were associated with Ba-1.2 specificity. This relationship suggested a linkage disequilibrium between the two loci for the Ba antigens.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 40 (1984), S. 1039-1041 
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 325 (1984), S. 80-84 
    ISSN: 1432-1912
    Keywords: X537A ; Smooth muscle contractions ; Rabbit aorta ; Guinea-pig Taenia coli ; Metabolic inhibition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary the effects of X537A (Lasalocid) on contractions induced in vascular and intestinal smooth muscles were examined. High K-induced sustained contractions were inhibited by X537A with an IC50 of 2.8·10−6 M in rabbit aorta and 8.8·10−8 M in guinea-pig Taenia coli. Changing the Ca concentration in the medium did not modify the effect of X537A. X537A also inhibited the noradrenaline-induced contraction in aorta (IC50=7.0·10−8 M). In a solution without added glucose, the inhibitory effect of X537A on the K-induced contraction in aorta was augmented (IC50=1.5·10−8 M). Under hypoxic conditions, the inhibitory effects of X537A on the noradrenaline-induced contractions in aorta and on the K-induced contraction in T. coli were decreased (IC50〉10−5 M and 3.2·10−6 M, respectively). X537A inhibited the K-induced increase in cellular 45Ca content in aorta measured by a modified lanthanum method. However, the IC50 for 45Ca uptake (6.6·10−7 M) was lower than that for K-induced contraction. In both tissues, X537A decreased the ATP content. Oxygen consumption of rat liver mitochondria was inhibited by X537A. From these results, it is concluded that the inhibitory effect of X537A on the noradrenaline-induced contraction in aorta and the K-induced contraction in T. coli, but not the K-induced contractions in aorta, may be due to the inhibition of aerobic metabolism.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 39 (1983), S. 786-787 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Although karyotype analyses by G-band staining have been used routinely in mammals, birds and reptiles, few have been reported in amphibia. We succeeded, however, in differential chromosome staining of some chromosomes of the African clawed toad,Xenopus laevis, by using the trypsin technique.
    Type of Medium: Electronic Resource
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