ISSN:
1432-0428
Keywords:
Meal size
;
sequence
;
time of day
;
carbohydrate tolerance
;
insulin action
;
insulin secretion
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The effects of size, time of day and sequence of meal ingestion were determined in healthy subjects using a Latin square design. Plasma glucose, insulin and gastric inhibitory polypeptide, but not glucagon, were correlated with meal size. Plasma glucose, but not insulin, gastric inhibitory polypeptide or glucagon, were greater later in the day. The progressive decline in carbohydrate tolerance from 08.00 to 18.00 h was associated with impaired insulin secretion estimated by C-peptide, and with impaired insulin action.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00253193
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