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  • 1980-1984  (2)
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  • 1
    Digitale Medien
    Digitale Medien
    Establishment of a Long-Term Cultured Suppressor T-Cell Line Specific for Guanosine (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 20 (1984), S. 0 
    Details
    ISSN: 1365-3083
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Induction of suppressor cells specific for gmmosine in C57BL/6 mice with syngeneic spleen cells coupled with guanosine was demonstrated. Spleen cells from mice that had been tolerized by the injection of guanosine-coupled syngeneic spleen cells (G–SC) were repeatedly stimulated with mitomycin C-treated G-SC (MMC-G-SC) in vitro. These cells effectively suppressed the secondary in vitro response to guanosine–keyhote limpet haemocyanin (G–KLH) but did not suppress the response to sheep erythrocytes (SRBC). From these cell populations a long-term-cultured suppressor T-cell line specific for guanosine was established by using interleukin-2 and MMC-G-SC. This cell line suppressed the response to G-KLH but did not suppress the response to trinitrophenyl–KLH and SRBC. The suppressive effect was completely eliminated by treatment with anti-Thy 1.2 and complement
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-3083.1984.tb01037.x
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  • 2
    Digitale Medien
    Digitale Medien
    Enrichment of IL-2-Producer T Cells from Mouse Spleen by Use of Bauhiniapurpurea Lectin (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 18 (1983), S. 0 
    Details
    ISSN: 1365-3083
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Bauhinia purpurea agglutinin (BpA) was used to enrich the interleukin 2 (IL 2)-producing T-cell subset from mouse spleen. IL 2 was found to be produced by the BpA-non-agglutinated (BpA−) T cells of mouse spleen on stimulation with concanavalin A (Con A). The degree of IL 2 production by BpA-agglutinated (BpA+) T cells was significamly low. The prolifcrative response to Con A of BpA− T cells was not influenced by the addition of exogenous IL 2, whereas BpA+T cells were partially dependent on the exogenous addition of IL 2 in the proliferative response.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-3083.1983.tb00860.x
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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