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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 60 (1982), S. 991-996 
    ISSN: 1432-1440
    Keywords: Histamine ; Obstructive air way disease (OAD) ; Oversensitive bronchial system ; Histamine receptors ; Histamin ; Bronchokonstriktion ; überempfindliches Bronchialsystem ; Histamin-Rezeptoren
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es besteht eine statistisch strenge Korrelation zwischen dem Anstieg der Histaminkonzentration im arteriellen Plasma und dem Anstieg der Strömungswiderstände in den Atemwegen bei experimentell verursachter allergischer Atemwegsobstruktion. Das Histamin wird an sensorischen Rezeptoren im Sinne einer Reflexbronchokonstriktion wirksam. Histamin verursacht in geringen Konzentrationen im Bronchialsystem eine unspezifische Empfindlichkeitssteigerung. Diese kann auch durch Allergene in sehr geringer Konzentration hervorgerufen werden. Patienten mit chronisch obstruktiver Bronchitis haben hohe Histamin-Konzentrationen im Sputum. Durch Waschungen der inneren Oberfläche des Bronchialbaums lassen sich hohe Histamin-Konzentrationen in der Spülflüssigkeit nachweisen. Die Gabe gleicher Histamin-Konzentrationen intravenös verursacht Bronchokonstriktion. Es ist anzunehmen, daß Histamin-Rezeptoren nahe der Oberfläche der Bronchialschleimhaut vorhanden sind. Ebenso müssen in der Oberfläche oder auf der Oberfläche der Bronchialschleimhaut Mastzellen vorhanden sein.
    Notes: Summary There is a statistically strong correlation between the increase of the histamine concentration in the arterial plasma and the increase of airway resistance. The histamine causes a reflex bronchoconstriction on the sensory receptors. Histamine in low concentration increases the unspecific reaction in the bronchial system. This can also be achieved using low concentrations of allergen aerosols. Patients with chronic obstructive bronchitis show high concentrations of histamine in the sputum. The bronchoconstrictive potency of this histamine was found to be not always active. Higher concentrations of histamine can be liberated by washing the inner surface of the bronchial tree. Histamine injected in similar concentrations as that measured in the sputum causes bronchoconstriction. There should be high concentrations of histamine receptors as well as mast cells near the surface of the mucosa of the bronchial wall. There are many questions remaining open, which will be discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 3 (1984), S. 438-438 
    ISSN: 1573-4811
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Plant and soil 61 (1981), S. 473-477 
    ISSN: 1573-5036
    Keywords: Allelopathy ; Brassica campestris spp.pekinensis ; Decomposing ; Chinese cabbrage residues ; Vigna radiata
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary Decomposing debris of Chinese cabbage was found to be harmful to a following mungbean crop grown in the greenhouse. Aqueous or methanolic extracts of decomposing Chinese cabbage residues in soil inhibited the seed germination of mungbean, and the growth of mungbean seedlings. The same effect was observed when mungbean was grown in soil in which Chinese cabbage had previously been grown. No toxicity was found in aqueous extracts of fresh Chinese cabbage shoot or root tissues.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Digestive diseases and sciences 29 (1984), S. 207-212 
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To evaluate the gastric emptying time of pharmaceutical dosage forms in a clinical setting, a relatively simple dual-radionuclide technique was developed. Placebo tablets of six different combinations of shape and size were labeled with indium-111 DTPA and enteric coated. Six volunteers participated in a single-blind and crossover study. Tablets were given in the morning on a fasting stomach with 6 oz of water containing99mTc pertechnetate and continuously observed with a gamma camera. A scintigraph was obtained each minute. The results suggested that the size, shape, or volume of the tablet used in this study had no significant effect in the rate of gastric emptying. The tablets emptied erratically and unpredictably, depending upon their time of arrival in the stomach in relation to the occurrence of interdigestive myoelectric contractions. The method described is a relatively simple and accurate technique to allow one to follow the gastric emptying of tablets.
    Type of Medium: Electronic Resource
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