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  • 1
    Electronic Resource
    Electronic Resource
    Natural electrical RF oscillation from cells (1981)
    Springer
    Journal of bioenergetics and biomembranes 13 (1981), S. 149-169 
    Details
    ISSN: 1573-6881
    Keywords: Oscillatory rf ; polarizable powders ; microdielectrophoresis ; density inhibition of cell division ; invasiveness of oncogenic cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Physics
    Notes: Abstract Electrical oscillatory rf phenomena are present during the division of cells. These were examined by studying the attraction of cells for polarizable powders. They are understood to occur by a process termed microdielectrophoresis (μ-DEP), the motion induced by a nonuniform electric field acting on a polarizable body. The suggestion that an electrical oscillatory aspect may also be involved in the “contact” or density inhibition of cell division and the mechanisms that may cause invasiveness of oncogenic cells are theoretically explored (i.e., changes in either the power level or the frequency of the oscillatory phenomena associated with cell division, or in the degree of electrical insulation of the cell from electrical damping by nearby cells). A number of experiments to test this hypothesis are suggested.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00763837
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  • 2
    Electronic Resource
    Electronic Resource
    Cellular spin resonance of aging yeast and mouse sarcoma cells (1982)
    Springer
    Journal of biological physics 10 (1982), S. 17-30 
    Details
    ISSN: 1573-0689
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract The way in which individual cells may be made to spin by the application of alternating electric fields is examined. The spinning of a given living cell is observed to respond rather sharply and in a resonant manner at several frequencies, hence the term "cellular spin resonance" (CSR). The frequencies of the applied field can be orders of magnitude higher than the actual spin rate. The CSR varies with the conductivity of the medium, with the square of the applied field, with the cell type and with the phase of the yeast cell life cycle. Living cells respond readily and individually are sharply resonant. Dead cells show little such response. From the behavior of the CRS in sinusoidal AC, as compared to pulsed DC, it appears likely that one cause of CSR, at least that in high frequency electric fields, is the presence of natural rf oscillations arising from the cells, and modulated by their high polarizability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01988465
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  • 3
    Electronic Resource
    Electronic Resource
    Cellular spin resonance in rotating electric fields (1982)
    Springer
    Journal of biological physics 10 (1982), S. 223-226 
    Details
    ISSN: 1573-0689
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract Cells and certain other electrically polarizable objects can be seen to spin when in a rotating electric field. When a rotating field (from four Pt electrodes) is applied over a frequency range of 500 to 75,000 Hz, living cells exhibit two or three response peaks, whereas dead cells exhibit only one response peak. Yeast (Saccharomyces cerevisiae) exhibit two peaks. The nature of these cellular spin resonances is under active study.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01991942
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  • 4
    Electronic Resource
    Electronic Resource
    Bioelectrochemistry: Ions, surfaces, membranes (1983)
    Springer
    Journal of biological physics 11 (1983), S. 14-14 
    Details
    ISSN: 1573-0689
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01857968
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  • 5
    Electronic Resource
    Electronic Resource
    Cellular spinning in pulsed rotating electric fields (1983)
    Springer
    Journal of biological physics 11 (1983), S. 59-62 
    Details
    ISSN: 1573-0689
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract Living cells, dead cells, and other particles suspended in aqueous media of low conductivity can be easily caused to spin if a rotating electrical field is applied. The background and theory are presented for the use of three-electrode systems provided with seriate square electrical pulses to spin cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01872942
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  • 6
    Electronic Resource
    Electronic Resource
    Electrical fusion of cells and nucleiin vitro: A preliminary note (1983)
    Springer
    Journal of biological physics 11 (1983), S. 63-65 
    Details
    ISSN: 1573-0689
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract The electrical fusion of male skin fibroblasts of the Indian muntjac (Muntiacus muntjak)in vitro is described. Fusion of cell nuclei in the resulting multinucleated giant cells was observed after application of up to ten additional DC pulses. Electrical fusion of bovine erythrocytes and alveolar macrophages is also described. Cell fusion can be obtained without the use of protease pretreatment, but the yield of fused cells is about 20 times lower than with prior use of proteases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01872943
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  • 7
    Electronic Resource
    Electronic Resource
    The spinning of suspended particles in a two-pulsed, three-electrode system (1983)
    Springer
    Journal of biological physics 11 (1983), S. 66-68 
    Details
    ISSN: 1573-0689
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract Suspended particles can be made to spin while in suspension in a medium and subject to a rotating electric field. The theory given here is for an electrical system comprised of three symmetrically spaced electrodes, one grounded, the other two given successive pulses. The theory provides the background for the application of such techniques to examine the dielectric properties of single cells or other living or nonliving particles.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01872944
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  • 8
    Electronic Resource
    Electronic Resource
    Cellular spin resonance: Theory and experiment (1983)
    Springer
    Journal of biological physics 11 (1983), S. 98-102 
    Details
    ISSN: 1573-0689
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract Living and dead cells, as well as certain inanimate particles, can be made to spin in a rotating electric field, such as that produced by a four-pole electrode system. The theory for the effects and the experimental results for a number of cells are given. Yeast cells (Saccharomyces cerevisiae, dead, and as protoplasts;Schizosaccharomyces octospora); an alga (Chlorella pyrenoidosa); mouse myeloma cells; human Hela cells; and several model particles were studied. Their spectra of spin response are shown to agree with the theory presented. Interestingly, live cells spin in a contrafield direction, while dead ones spin co-field in the low-frequency range. The result indicate that this new technique of cellular spin resonance (CSR) will be useful in determining the effective dielectric constant of individual cells, for the direction and magnitude of the CSR is directly proportional to the effective dielectric constant, and the spin rate can readily and directly be determined over a wide frequency range.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01873190
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  • 9
    Electronic Resource
    Electronic Resource
    A mass polarizability molecular beam spectrometer (1983)
    Springer
    Journal of biological physics 11 (1983), S. 103-110 
    Details
    ISSN: 1573-0689
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract A molecular beam spectrometer using dielectrophoresis is described which should be useful in studies of molecular polarizabilities, dipole moments, rotational energy states, and reaction rates. The special electrode system produces a constant force over a wide spatial region (hence is “isomotive”) on nonpolar and simple polar molecules. Design optima and calculations of the obtainable forces, beam intensities, and resolutions are given for some typical molecules (methane, naphthalene, hydrogen chloride) for the proposed instrument. The isomotive field geometry affords a gain in beam strength over other designs, permitting the use of velocity-selected beams in a spectrometer having a circular beam path. It is capable of separating molecules on the basis of either mass or polarizability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01881328
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  • 10
    Electronic Resource
    Electronic Resource
    Dynamic dielectrophoretic levitation of living individual cells (1980)
    Springer
    Journal of biological physics 8 (1980), S. 18-31 
    Details
    ISSN: 1573-0689
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract The levitation of lone live cells by means of dielectrophoretic force provides a means of determining the relative polarization of the cells and their aqueous support medium. When done over a range of frequencies, a spectrum of dielectric (polarization) responses is obtained which serves to characterize a single living ell. In this manner, individual cells of several microorganisms,Saccharomyces cerevisiae andNetrium digitus, were investigated in the frequency range 102 to 106 Hz. These and related prior studies showed that the positive dielectrophoresis, i.e. where the suspended particle has a greater net polarization than the suspending medium, can be — used to show subtle differences between species, and even between cells of the same culture when using this technique.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02250940
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