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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 62 (1984), S. 998-1000 
    ISSN: 1432-1440
    Keywords: Prajmaliumbitartrate ; intrahepatic cholestasis ; Liver (drug effects) ; Antiarrhythmic agents (adverse effects)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Seven further cases with n-propyl-ajmaliumbitartrate (NPAB)-associated liver damage observed between 1976 and 1980 in two collaborating institutions are reported. The cause/effect relationship could be classified as probable in three cases and as potential in the remaining four patients. No drug rechallenge was carried out. In the clinical management, definite exclusion of biliary tract obstruction had a clear priority over histologic documentation of the degree of the transient liver damage. Follow-up data after 2 years 8 months to 5 years 9 months by personal reinvestigation of three patients and by questionnaire to family physicians and patients in the remaining four cases gave no clinical or serologic indication of persisting or relapsing liver damage. Liver biopsies were not considered to be warranted in the follow-up of these asymptomatic patients with normal liver function tests.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    The journal of membrane biology 70 (1982), S. 147-155 
    ISSN: 1432-1424
    Keywords: black lipid membranes ; carrier-mediated ion transport ; lipid mixture ; Ca++-induced phase separation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary Voltage jump-current relaxation experiments have been performed with valinomycin-doped membranes of mixtures of 1,2-dipentadecylmethylidene-glycero-3-phosphorylcholine (PC) and charged-phosphatidic acid (PA). Both relaxation processes predicted by a simple carrier model could be resolved which allowed the calculation of the rate constants of the Rb+ transport. The dependence of the rate constants on the membrane composition indicates that (i) the lipids in the mixed membranes are homogeneously distributed and that (ii) no major difference exists between the composition of the membrane and that of the torus. The analysis of the stationary conductance data, however, shows that the valinomycin content of the mixed membranes depends strongly on their lipid composition. Addition of Ca++ ions to a 1∶1 mixture induces a phase separation into PA domains of very low conductivity and PC-enriched regions of high conductivity. Half saturation is reached atc ca=5×10−4 m. At 10−2 m Ca++ in the aqueous phase, the rate constants clearly indicate that all PA molecules are electrically “passivated” and only pure PC domains contribute to the membrane current. A detailed picture is thus derived of the coupling of a model transport system to the externally triggered membrane reorganization.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 14 (1982), S. 0 
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 47 (1982), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Sectioned and formed roast beef, vacuum mixed and heat processed in either retortable pouches or cans, had a lower cook yield than its nonvacuum mixed counterpart. Vacuum mixing had no significant influence on increasing particle-to-particle cohesion (binding strength). Sectioned and formed roast beef cooked in retortable pouches at 121°C (Fo= 6.0) had a higher cook yield and binding strength than product processed at 110°C (Fo= 6.0). Processing the canned product at 121°C (Fo= 6.0) as opposed to 110°C (Fo= 6.0) resulted in no improvement of cook yield or binding strength. Overall, product processed in retortable pouches had a higher binding strength, but a lower cook yield than product processed in cans.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 45 (1980), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Three major ham muscles were isolated, trimmed, and placed in a tumbler either 4 or 48 hr postmortem with 18% curing solution. Either vacuum or no vacuum was applied. Brine absorption within whole muscles was monitored by taking samples at three different depths during 13.47 hr of intermittent tumbling and after the curing period at 24 hr. Results indicate that vacuum and prerigor state independently increase the absorption of NaCl (P 〉 0.01). After the first hour of continuous tumbling the outer sample depth attained 2.15% NaCl and then decreased, but the concentration of NaCl in the inner two depths increased linearly with log time (P 〉 0.01). After 24 hr a homogeneous cure distribution was not found as the NaCl content in the depths was markedly different. Breaking strengths of ham slices were found to be greater when vacuum tumbling was used (P 〉 0.001). Thus vacuum is implicated in increased cure absorption and binding functionality.
    Type of Medium: Electronic Resource
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  • 6
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 47 (1982), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The effects of vacuum mixing and precooking on the binding strength and cook yield of restructured steaks were evaluated. Vacuum mixing was responsible for an increased binding strength of the restructured steak, but had no effect on the cook yield. Precooked, reheated steaks had a significantly higher binding strength, but a lower cook yield than steaks cooked from the frozen, raw state.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 45 (1980), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: This experiment was designed to determine the effects of vacuum mixing and rigor state on protein extraction and functionality of beef. Beef muscles excised either pre- or postrigor from cow chucks, were ground. The pre- or postrigor ground mince with Weber-Edsall solution was mixed using 3 different mixing times in a Keebler mixer. Either vacuum or no vacuum was utilized during mixing. Following mixing, a procedure to precipitate crude myosin (CM) from each treatment was performed. Results indicate that significantly greater amounts of CM were obtained due to vacuum treatment (P 〈 0.05) and with increased time of mixing (P 〈 0.01). Comparing pre- and postrigor vacuum mixed meat, the former produced greater CM yields over time (P 〈 0.01). Protein functionality of CM fractions was evaluated using binding ability and least concentration gel tests. Mixing time caused a linear decrease in binding ability (P 〈 0.05) and an increase in the amount of protein to form a gel, irrespective of vacuum. Delineation of the functionality differences was attempted using or-helical content, thermal melting curves, and SDS-PAGE. Implication of effects of vacuum mixing duration in relation to processed meats is discussed.
    Type of Medium: Electronic Resource
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  • 9
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    Unknown
    Washington, etc. : Periodicals Archive Online (PAO)
    Explicator. 40:3 (1982:Spring) 44 
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 352 (1980), S. 522-522 
    ISSN: 1435-2451
    Keywords: Recurrent ulcer ; Diagnostic ; Individual surgical treatment ; Rezidivulcus ; Funktionelle Diagnostik ; Individualisierende Operation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Auswahl des Operationsverfahrens im Korrektureingriff wegen eines Rezidivulcus sollte der vielschichtigen Pathogenese gerecht werden. Die Indikation zur konservativen Behandlung oder operativer Korrektur (Vagotomie oder Resektion alleine oder kombiniert) hängt wesentlich ab vom Ausfall präoperativer Funktionsteste, welche Röntgenuntersuchung, Sekretionsanalyse, Gastrinprofil nach Provokation und nuklearmedizinische Messungen von Magenentleerung und Gallereflux einschließen. Die guten Erfahrungen mit einem abgestuften Indikationsschema werden an 135 Fällen (94 Upj, 41 Rezidiven nach Vagotomie) dargestellt.
    Notes: Summary The choice of treatment (medical or surgical with single vagotomy or resection or a combination of the two methods) in recurrent ulceration after resection or nonresection depends on the results of different functional studies before reoperation. They include X-ray examination, secretion analysis, determination of serum gastrin in provocation and feeding tests, and measurement of gastric emptying and jejuno- or duodenogastric reflux by scintiscan. Good results are reported in 135 cases with the use of different procedures based on functional diagnostic parameters.
    Type of Medium: Electronic Resource
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