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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 65 (1984), S. 41-45 
    ISSN: 1432-0533
    Keywords: Colloid cyst ; Third ventricle ; Ultrastructure ; Pathogenesis ; Rathke's cyst
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The case involves a colloid cyst of the third ventricle in a 20-year-old man. The lining epithelia of the cyst were composed of two different types of epithelial cells; stratified squamous cells and mucincontaining columnar cells. The presence of both squamous and glandular cells in the cyst wall supports the contention that the colloid cyst in the present case derived from an non-neuroepithelial source. The clinico-pathology of this cystic tumor is compared here with other epithelial cysts of the central nervous system (CNS), especially Rathke's cyst.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0533
    Keywords: Pleomorphic polyglucosan body ; Bielschowsky body ; Lafora body ; Corpora amylacea
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A rare case with pleomorphic intra-neuronal polyglucosan bodies is reported. A 45-year-old man died of gastric carcinoma with extensive visceral involvement. The autopsy showed numerous intra-neural pleomorphic PAs-positive deposits reminiscent of Bielschowsky bodies in the lateral segments of the pallidum, substantia nigra, and brain stem on both sides. Their histochemical properties were consistent with polyglucosan. The bodies were ultrastructurally composed of filamentous structures and seen in perikarya, axons, and dendrites. Occasionally, spotty electron-dense material was seen in the center of the bodies. The filaments were selectively stained with thiocarbohydrazide method after Thiéry, indicating their chief component as glucose polymers. The bodies are compared with Bielschowsky bodies, Lafora bodies, corpora amylacea, and related bodies, and their nature and significance are briefly discussed.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 138 (1982), S. 357-358 
    ISSN: 1432-1076
    Keywords: Menkes' syndrome ; Cataract
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 2-year and 9-month-old boy with Menkes syndrome is reported. In addition to the typical features of this syndrome our patient had bilateral cataracts. The relation between abnormal copper metabolism and cataract is discussed.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1076
    Keywords: Atypical PKU ; Deficiency of dihydrobiopterin ; Neurotransmitter treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A fourteen month-old boy with atypical phenylketonuria was treated with 5-hydroxytryptophan, L-dopa and peripheral aromatic amino acid decarboxylase inhibitor (Ro 4-4602:benserazide). Despite the good control of plasma phenylalanine on a low phenylalanine diet, he had shown no improvement in his development but progressive neurological symptoms, such asiirritability, convulsions and decrease voluntary movement. After beginning neurotransmitter therapy, his irritability disappeared promptly and the other symptoms diminished. He gradually reached his developmental milestones. At two and a half years of age, he had recovered sufficiently to be able to walk freely on treatment with 13 mg/kg/day of 5-hydroxytryptophan, 11 mg/kg/day of L-dopa and 2.7 mg/kg/day of benserazide in combination with slight restriction of phenylalanine intake (100 mg/kg/day). Levels of serotonin and 5-hydroxyindoleacetic acid were low in the patient's CSF. His urinary biopterin (Crithidia factor) excretion was low. An increase in serum biopterin following L-phenylalanine loading was not found. Dihydropteridine reductase activity in his skin fibroblasts was normal. He excreated large amounts of erythro- and threo-neopterins (but only a trace of biopterin) in his urine. After loading with phenylalanine the urinary excretion of neopterins was even more enhanced, but biopterin remained at low levels. These findings indicated that the patient has a dihydrobiopterin synthetase deficiency.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0942-0940
    Keywords: Brain tumours ; LDH isoenzyme ; cytochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The lactate dehydrogenase (LDH) isoenzyme patterns in benign and malignant brain tumours were determined by means of electrophoresis of the cell extracts and selective cytochemical stain of the smears. The LDH isoenzyme distribution of the cell extracts showed a pronounced cathodal shift in the malignant gliomas and metastatic carcinomas. Normal brain tissues and histologically benign gliomas, however, showed an anodal pattern with a dominance of the H-type LDH. Schwannomas and meningiomas had a midzone isoenzyme pattern with a dominant LDH3 fraction. Pituitary adenomas usually showed the LDH pattern similar to that of the normal cerebrum. The LDH M fraction could be cytochemically verified using an inhibitory effect by 2.6 M urea in staining. Astrocytomas grades 3–4 and metastatic carcinomas were characterized by loss or marked reduction of stainability by urea treatment, while astrocytomas grades 1–2 and oligodendrogliomas were resistant to urea inhibition.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Growth of influenza B viruses is restricted at high temperatures. Within B/Yamagata-infected MDCK cells, the synthesis of the M protein was selectively inhibited at 39° C, accompanied by a reduced production of virus particles.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Archives of virology 82 (1984), S. 111-117 
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Nine strains of influenza C virus were compared in their growth characteristics and viral polypeptides using LLCMK2 cells. The results suggested that influenza C virus undergoes genetic changes like influenza A or B virus.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A genetic cross was performed between influenza viruses B/Yamagata/1/73 and clone 6–10, an A type influenza virus derived from a cross between A/Aichi/2/68 (H3N2) and B/Yamagata. Efficiency of plating of B/Yamagata at 39.5° C was less than 10−3 in MDCK cells, while that of clone 6–10 or A/Aichi was higher than 10−1. Four of the 15 clones selected for HA of Aichi serotype from the mixed yield, where type B virus was predominant over type A, were temperature-sensitive(ts), with efficiency of plating at 39.5° C less than 10−2, exceeding the frequency of spontaneousts mutants among clone 6–10 progeny. Thus, co-existing type B virus not only interfered with the replication of type A, but also rendered it temperature-sensitive. Genetic analysis of the 4ts clones using a set ofts mutants of influenza virus A/WSN (H0N1) revealed that these clones, in contrast with the spontaneousts mutant of clone 6–10, withts defect only in NP gene, possessedts lesions in multiple genes including a commonts defect inm. Polyacrylamide gel electrophoresis of viral RNA and proteins of these clones showed an identical gel pattern to that of clone 6–10, although the rate of synthesis of individual viral polypeptide was variable from clone to clone.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1573-8248
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Description / Table of Contents: Résumé Les interactions de développement entre un endoparasitoïde grégaire,Apanteles kariyai Watanabe et son hôte,Leucania separata Walker, ont été étudiées. Le parasitoïde a pondu un plus grand nombre d'œufs dans l'hôte plus âgé. La taille de l'hôte a montré une augmentation graduelle avec l'avancement du stade larvaire, mais l'augmentation en nombre des œufs pondus par de parasitoïde n'a pas été parallèle à l'augmentation graduelle de la taille de l'hôte. Le poids net de l'hôte a été en corrélation positive avec le nombre des œufs pondus par le parasitoïde ainsi qu'avec le poids total des larves du parasitoïde. Par conséquent plus les parasitoïdes sont en nombre, plus ils contribuent à l'augmentation de la taille de l'hôte.
    Notes: Abstract The developmental interactions between a gregarious endoparasitoid,Apanteles kariyai Watanabe and its host,Leucania separata Walker, were investigated. The parasitoid laid more eggs in older hosts. Host size increased gradiently as the instar advanced, but the number of eggs laid per host did not increase accordingly. The net weight of the host was correlated positively with the number of eggs laid and with the total weight of parasitoids, especially in cases of parasitization at 3rd (5th-instar type), 4th and early 6th instar where the correlation was significant at 1% level. It follows therefore that the more parasitoids there are relative to their host size, the more they contribute to make the host size larger.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 307 (1984), S. 251-252 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The experimental procedures used are almost identical to those of Tanaka and Masuda2. About 0.7 to 3 g of each sample was decomposed. Rare-earth elements (REE) were separated from the major elements by an AG50W-X8 resin column in HC1 media, while Ce and Nd were separated using an AG50W-X8 resin ...
    Type of Medium: Electronic Resource
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