ISSN:
0009-2940
Keywords:
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Description / Table of Contents:
Orthoamides, IX: Reaction of CH-Acidic Compounds with Amide Acetals, an Aminal-tert-butylester and Tris(dimethylamino)methaneOrthoamides react with hydrogen cyanide and alkynes to give 2-dimethylamino-2-alkoxy-nitriles (2, 4, 6, 8, 10), 2,2-bis(dimethylamino)nitriles (12,12a), and 3,3-bis(dimethylamino)-alkynes (14-16). Methane derivatives heated with dimethylformamide diäthylacetal (1) react to form the alkylated methane derivatives (25, 26, 28, 29, 30, 34), whereas under mild conditions methane derivatives react with the aminal tert-butylester 11 to produce tetramethyl-formamidinium salts (31, 32, 33, 35).
Notes:
Orthoamide reagieren mit wasserfreier Blausäure und Alkinen zu 2-Dimethylamino-2-alkoxy-nitrilen (2, 4, 6, 8, 10), 2.2-Bis-dimethylamino-nitrilen (12, 12a) und 3.3-Bis-dimethylamino-alkinen-(l) (14-16). Aus Methan-Derivaten und Dimethylformamid-diäthylacetal (1) ent-stehen in der Wärme die alkylierten Methan-Derivate (25, 26, 28, 29, 30, 34) und mit dem Aminal-tert.-butylester 11 unter milden Reaktionsbedingungen die Tetramethylformamidini-um-Salze(31,32, 33,35).
Additional Material:
2 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19701030129
Permalink
