ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] The choice of the pivaloyl blocking group at the amino-terminal was dictated by the necessity of maintaining the first amide bond in a trans configuration. While X-Pro bonds can exist in both cis and trans configurations in solution6, the bulky tertiary butyl group locks the piv-Pro bond into the ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/281083a0
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