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  • 1980-1984  (13)
  • 1975-1979  (13)
  • 1905-1909  (1)
  • 1
    Digitale Medien
    Digitale Medien
    The “Double-Coller” Technique For EEG Electrode Preparation and Placement (1975)
    Oxford, UK : Blackwell Publishing Ltd
    Psychophysiology 12 (1975), S. 0 
    Details
    ISSN: 1469-8986
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin , Psychologie
    Notizen: For accurate and reliable EEG recording. electrode resistances must be kept relatively low and constant. To ensure that these conditions are met, a fixing agent, collodian, is usually used to fix the electrodes firmly to the scalp. Collodian, however, produces many unwanted side effects. A “double-cllar” method of electrode placement is described whereby electrodes may be firmly fixed to the scalp without the use of collodian. This technique is both faster and less troublesome than the use of collodian. Using this technique, electrode resistances at vertex and occiput were well below generally acceptable criteria (averaging under 5000 ohms) and there was no significant increase in resistance at either placement following nearly 2 hrs of continuous EEG recordings. It is concluded that, under certain laboratory conditions, the “double-collar” method of electrode preparation and placement is superior to the use of collodian.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1469-8986.1975.tb00031.x
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  • 2
    Digitale Medien
    Digitale Medien
    The Duhring chamber assay for corticosteroid atrophy (1981)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 104 (1981), S. 0 
    Details
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: A new human model for the evaluation of the atrophogenicity of topical corticosteroids is proposed. Formulated corticosteroids (creams and ointments) were applied occlusively to normal forearm skin of human volunteers for 3 weeks using Duhring chambers. Visible atrophy and telangiectasia were rated under a stereomicroscope on a histologically validated five-point scale. There was a close correlation between the parameters of atrophy and telangiectasia. Atrophogenicity varied considerably among the tested corticosteroids, ranging from none (1% hydrocortisone) via moderate (0.1% betamethasone valerate) to very severe (0.05% clobetasol propionate). A dose-response relationship with exposure time and concentration of the corticosteroid could be demonstrated. Furthermore, the vehicle influenced the resulting atrophy and telangiectasia. Fatty ointments seem to pose less risk than oil in water creams.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2133.1981.tb01712.x
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  • 3
    Digitale Medien
    Digitale Medien
    STEROID ADDICTION (1979)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of dermatology 18 (1979), S. 0 
    Details
    ISSN: 1365-4632
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-4362.1979.tb01905.x
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  • 4
    Digitale Medien
    Digitale Medien
    Cutaneous biometrics I. The response of human skin to dimethyl sulphoxide (1980)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 103 (1980), S. 0 
    Details
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: The wealing response of human skin to dimethyl sulphoxide (DMSO) has been quantified. Concentrations of 90%, 95%, and 100% were applied for 5 min to circular areas 8 mm in diameter. Wealing was scored on a five-point scale after 10 min.Marked individual variations were found. Wealing was strongly influenced by body region and was dose-dependent. The intensity of the reaction paralleled that to other irritants and was dependent mainly on thickness and integrity of the horny layer. The DMSO test is a simple, quick way to assess the barrier function of the stratum corneum.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2133.1980.tb07243.x
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  • 5
    Digitale Medien
    Digitale Medien
    Eosinophil chemotactic factor (ECF) in blister fluid of dermatological diseases (1980)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 102 (1980), S. 0 
    Details
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: The occurrence of low molecular weight (〈 500 dalton) eosinophil chemotactic factor (ECF) was studied in the blister fluid of patients with various dermatological diseases by an in vitro chemotaxis method. After chromatographic separation of the test substance on a small Sephadex G 25 column, ECF was demonstrated in blisters of five patients with bullous pemphigoid, in three patients with systemic drug reactions and in one patient with blisters after contact with primula. ECF was not found in blisters of patients with epidermolysis bullosa and herpes gestationis or in DNCB-induced blisters. Fluid obtained from suction blisters was negative in normal controls and on unaffected skin of patients with atopic eczema, but contained ECF in eczematous areas. The demonstration of ECF in tissue fluid suggests that this factor plays a role in the local accumulation of eosinophils at sites of certain inflammatory reactions.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2133.1980.tb05670.x
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  • 6
    Digitale Medien
    Digitale Medien
    Rapid blister formation in human skin with ammonium hydroxide (1977)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 96 (1977), S. 0 
    Details
    ISSN: 1365-2133
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: The topical application to human skin of a 1:1 aqueous solution of ammonium hydroxide in a well drilled into a plastic block will provoke an infra-epidermal blister in an average time of about 13 min.The blister roof can be used for physico-chemical analyses of the horny layer while the base is suitable for studies of wound healing, bacterial infections, etc.The minimal blistering time (MBT) increases directly as the number of cell layers of the stratum corneum and ranges from 3 to 57 min in different regions and persons. The intensity of the dermatitis provoked by a 24 h exposure to sodium lauryl sulphate is strongly correlated with the MBT. The latter is therefore a reliable measure of cutaneous irritability.The blisters are virtually painless. The inflammatory reaction clinically and histologically is slight. Healing is rapid without scarring.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2133.1977.tb07148.x
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  • 7
    Digitale Medien
    Digitale Medien
    The Duhring chamber (1979)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 5 (1979), S. 0 
    Details
    ISSN: 1600-0536
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: For assessing skin reactions in irritants and allergens, chambers which confine the test substance to the site of application are much superior to conventional patch tests. Because the concentration and volume do not change appreciably, the method allows for quantification and yields more reproducible results.A new aluminum chamber has been designed which is more useful than its predecessor, the Finn chamber, mainly because of its increased capacity. Data are given to show that the intensity of irritant and allergic reactions is dependent on the quantities applied.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-0536.1979.tb04802.x
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  • 8
    Digitale Medien
    Digitale Medien
    The chamber-scarification test for irritancy (1976)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 2 (1976), S. 0 
    Details
    ISSN: 1600-0536
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: A procedure has been designed (the chamber-scarification test), which possesses greatly increased sensitivity for assessing the irritancy of topically applied materials. A forearm test site is criss-cross scarified by drawing a 30-gauge needle over the skin with just enough pressure to cleave the epidermis without drawing blood. The test agent is applied in an aluminum chamber once daily for 3 days.The advantages of the method over conventional patch testing are: enhanced capacity to measure mild irritants, reduced time (3 days versus 10 to 21 days), less effort, less cost, less discombort for the volunteers and greater reproducibility.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-0536.1976.tb03068.x
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  • 9
    Digitale Medien
    Digitale Medien
    GENERAL DISCUSSION (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 362 (1981), S. 0 
    Details
    ISSN: 1749-6632
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Allgemeine Naturwissenschaft
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1749-6632.1981.tb12798.x
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  • 10
    Digitale Medien
    Digitale Medien
    Regulation of enzyme levels by phytochrome in mustard cotyledons: Multiple mechanisms? (1977)
    Springer
    Planta 136 (1977), S. 181-186 
    Details
    ISSN: 1432-2048
    Schlagwort(e): Enzyme Regulation ; Sinapis alba ; Phytochrome ; Phenylalanine ammonia-lyase ; Ribulosebisphosphate carboxylase
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract Phytochrome controls the appearance of many enzymes in the mustard (Sinapis alba L.) cotyledons. The problem has been whether the effect of phytochrome on the appearance of enzymes in this organ is due to a common initial action of Pfr, e.g. due to the liberation of a “second messenger”. We have compared the modulation by light (phytochrome) of the appearance of phenylalanine ammonia lyase (PAL)+ and ribulosebisphosphate carboxylase (Carboxylase)+. PAL becomes detectable in the mustard cotyledons at 27 h after sowing while Carboxylase starts to appear only at 42 h after sowing (starting points, 25° C). The starting points cannot be shifted by light. As a major result, in the case of PAL the inductive effect of continuous red light (given from the time of sowing) remains fully reversible by 756 nm-light up to the starting point (27 h after sowing) while with Carboxylase full reversibility in continuous red light is lost at approximately 15 h after sowing. While the induction of Carboxylase is already saturated at a very low level of Pfr (e.g. continuous 756 nm-light saturates the response) and does not depend on irradiance (e.g. continuous 675 mW m-2 red light and 67.5 mW m-2 red light lead to the same time course), PAL induction is a graded response over a wide range of Pfr doses and depends strongly on the fluence rate (high irradiance response, HIR). It is concluded that PAL induction and Carboxylase induction are not only separated in time but differ in every regard except that both responses are mediated by phytochrome. The present data support the previous conclusion that the specification of the temporal and spatial pattern of development is independent of phytochrome even though the realization of the pattern of development can only occur in the presence of phytochrome (Pfr). It seems that there is no feedback from pattern realization to pattern specification.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00396196
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