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  • 1
    Electronic Resource
    Electronic Resource
    Polychlorinated biphenyl(s) as a promotor in experimental hepatocarcinogenesis in rats (1976)
    Springer
    Journal of cancer research and clinical oncology 87 (1976), S. 257-266 
    Details
    ISSN: 1432-1335
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effects of dietary polychlorinated biphenyls (PCBs) on hepatocarcinogenesis in female rats of Donryu strain receiving 3′-methyl-4-dimethyl-aminoazobenzene (3′-Me-DAB) were investigated. Oral administration of PCBs after administration of 3′-Me-DAB resulted in a high incidence (64%) of hepatocarcinoma. In contrast, administration of a similar amount of PCBs before, or together with 3′-Me-DAB did not induce hepatic tumors. Administration of a slightly larger amount of PCBs alone did not induce liver tumors, while administration of a slightly larger amount of 3′-Me-DAB alone caused only a low incidence (13%) of hepatocarcinoma. These results strongly suggest that PCBs exert a potent promoting action in experimental azo dye hepatocarcinogenesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00506498
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Ocular fundus photography of workers exposed to carbon disulfide — A comparative epidemiological study between Japan and Finland (1977)
    Springer
    International archives of occupational and environmental health 39 (1977), S. 97-101 
    Details
    ISSN: 1432-1246
    Keywords: Carbon disulfide ; Color fundus photography ; Retinal microaneurysms/small dot hemorrhages ; Retinopathia sulfocarbonica
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Using color fundus photography, the occurrence of retinopathy was studied in Japanese and Finnish viscose rayon workers and unexposed control subjects. Interobserver error was avoided by strict method control. Retinopathy (microaneurysms/small dot hemorrhages) was detected in 103 of 419 Japanese exposed (24.6%) and in 7 of 188 Finnish exposed subjects (3.79% (P 〈 0.05). The respective prevalences for the unexposed subjects were 3.8% and 2.6%. The retinopathy due to carbon disulfide, “retinopathia sulfocarbonica”, seen in Japanese viscose rayon workers did not occur in Finnish workers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00380889
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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