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Rate of offset of action of slow-acting muscarinic antagonists is fast (1977)

BOLTON, T. B.

[s.l.] : Nature Publishing Group

Nature 270 (1977), S. 354-356

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ISSN: 1476-4687

Source: Nature Archives 1869 - 2009

Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics

Notes: [Auszug] The iontophoretic application of ACh (typically using a 50-nA, 2.5-nC pulse) usually elicited a monophasic depolarisation with a latency of 0.1-1 s (Fig. 1) although bi- and polyphasic responses were also observed18. The sensitivity to ACh was tested every 16-20 s, or occasionally every 8 s, and in ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/270354a0

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