ISSN:
1432-0533
Keywords:
Mirochondria
;
Rat hypoglossal nucleus
;
Initial part of the axon
;
Regeneration
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The initial part of the axon including the axon hillock, the initial unmyelinated segment and the beginning of myelinated axon was studied electron microscopically during regeneration, 1–30 days following a crush lesion of the rat hypoglossal nerve. Large mitochondria reaching 1.1 μm in diameter, with abundant cristae and dense granules in the matrix were observed between days 3–21. They formed clusters in the initial myelinated segment of the axon. End-to-end contacts and ribosomes around them were very often visible. The large mitochondria exhibited strong succinate dehydrogenase and NAD · H2 diaphorase activities. The relationship between the appearance of large and active mitochondria in the initial part of the axon and the elevated axonal transport during regeneration of the peripheral nerve is also discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00685367
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